Bøger i Annals of the New York Academy of Sciences serien

Provides refereed reviews on learning theory and addition, deep brain stimulation and addiction, novel therapeutic approaches to addiction, developmental studies of reward, genetics and brain imaging in addiction, genetics of alcoholism and its comorbidities, in addition to other state-of-the art topics in addiction science.

Offers nascent mechanistic understanding of the molecular events driving the signal transduction of adhesion-GPCRs, novel models to evaluate their functions, and evidence for their involvement in human disease. This title summarizes various perspectives on NBCDs and the scientific and regulatory considerations associated with drug categories.

This is the inaugural volume in a new series of reviews. Each annual volume will contain authoritative reviews of developing research topics in antimicrobial therapeutics. Authors will describe how the research being reviewed can be applied to real-world problems.

* Part of the Annals of the New York Academy of Sciences series. *Annals volumes are available for sale as individual books or as a journal. For more information on subscriptions, please visit www. blackwellpublishing. com/nyas. .

To help commemorate the 200th anniversary of the New York Academy of Sciences, founded in 1817, this revised edition of Simon Baatz s book Knowledge, Culture, and Science in the Metropolis: The New York Academy of Sciences, 1817 2017, presents new material on the Academy s activities from 1970-2016.

Evolutionary Dynamics and Information Hierarchies in Biological Systems: Aspen Center for Physics Workshop. Organisms use a variety of mechanisms to store, interpret, and use information that is organized in a large and complex hierarchy from DNA sequences, to chromatin regulation, to intra/extracellular signaling, to tissue/organ organization, to the interactions between organisms and species. This Annals volume presents individual papers and a summarizing meeting report stemming from a workshop at the Aspen Center for Physics in Aspen, Colorado, organized to discuss these issues. The three themed weeks of the workshop focused on the organization of DNA into chromatin, epigenetic adaptation and host/pathogen interaction, and macroevolution. Although these areas represent a wide breadth of biological phenomena, several unifying themes emerged through workshop discussions. In particular, the differences between the simplicity of our theoretical models and the complex interactions characteristic of real physical systems were repeatedly highlighted. Workshop discussions therefore pointed to key areas where theory and observations should aim to converge as we refine our understanding of evolution.

This volume comprises contributions from faculty and postdoctoral finalists of the 2012 New York Academy of Science Blavatnik Awards for Young Scientists. The Awards recognize highly innovative, multidisciplinary accomplishments in the life sciences, physical sciences, mathematics, and engineering.

-This meeting report provides a synopsis of the conference -Play, Attention, and Learning: How Do Play and Timing Shape the Development of Attention and Facilitate Classroom Learning?,- held on June 15, 2012 and presented by the New York Academy of Sciences and the Brain Trauma Foundation. The report outlines important research steps that need to be taken in order to address critical questions about play, human activity, and cognitive functions. This meeting report presents a summary of the conference -Treatment-Resistant Depression: Glutamate, Stress Hormones, and their Roles in the Regeneration of Neurons,- held on March 25, 2013 at the New York Academy of Sciences. The report discusses how treatment with NMDA receptor antagonists and magnesium have shown the ability to sprout new synaptic connections and reverse stress-induced neural changes, opening up promising new territory for the development of drugs to meet the unmet need in patients with clinical depression. Also included in this Annals volume is a scholarly review on carbohydrate recognition in the immune system and contributions of neoglycolipid-based microarrays to carbohydrate ligand discovery---Academy website.

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a phenol phytoalexin derived from grapes, berries, and other plants possessing a spectrum of pharmacologic properties.

This volume is the eleventh published from a conference sponsored by the World Organization for Specialized Studies on Diseases of the Esophagus (OESO) and the second to be published in Annals.

Part of The Year in Evolutionary Biology series, this title includes reviews on: gene loss, thermogenesis, and the origin of birds; sexual selection in the light of molecular evolutionary genetics; the nine-spined stickleback, an emerging model in evolutionary biology; and the evolutionary consequences of interspecific aggression.

This volume stems from the conference "The Neurosciences and Music IV: Learning and Memory" held in Edinburgh, Scotland 9 12 June 2011. The volume focuses on four themes: infants and children; adult musicians and non-musicians; disabilities and aging-related issues; and therapy and rehabilitation.

This Annals volume includes invited short reviews on topics presented at the 7th International Cancer Vaccine Symposium Renaissance of Cancer Immunotherapy , held September 9-11, 2012 in Florence, Italy.

Aspergillosis, the leading fungal cause of mortality in immunocompromised patients, presents a serious worldwide challenge particularly in the face of increasing antifungal resistance.

This is the second of two Annals volume (see also Volume 1262) of papers by speakers at the 8th International Society for Neuroimmodulation Congress held in Dresden, Germany, October 2011.

The second of two volumes, Thymosins in Health and Disease II, continues the exploration of the rapidly expanding area of research in thymosins a family of proteins, with a broad set of biological properties and great clinical potential.

Tight junction proteins connect epithelial and endothelial cells and, importantly, form selective barriers and channels for paracellular transportation.

The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation.

This volume presents reports from recent scientific meetings on topics in emerging fields: (1) Diabetes and Oral Disease: Implications for Health Professionals; (2) The New York Stem Cell Foundation: Sixth Annual Translational Stem Cell Research Conference; and (3) Chronic Inflammatory and Neuropathic Pain.

This volume stems from the Second International Conference on Environmental Stressors in Biology and Medicine, which occurred October 5-7, 2011 in Siena, Italy.

This is one of two Annals volumes that present papers by speakers at the 8th International Society for Neuroimmodulation Congress held in Dresden, Germany, October 2011. The papers focus on interactions among the immune, endocrine, and nervous systems that occur at multiple levels, from intracellular pathways by immune and neuro-endocrine mediators, to the exchange of information between the three systems that results in physiologic and adaptive effects. In certain instances, however, these interactions may be unbalanced or even disrupted, which can contribute to pathology, and aspects of such pathobiology are presented in some of the contributions. This volume focuses on the basic science of immune-neuro-endocrine interactions.

This volume stems from the eighth international symposium and workshop entitled "Hematopoietic Stem Cells VIII" held hosted by the University of Tuebingen, Germany in the fall of 2011. The meeting was designed to bring ~30 leading scientists together to discuss the state-of-the-art in the field of hematopoietic stem cells.

Features major issues and topics in cognitive neuroscience, including the role of strategies in motor learning; efficient coding and the neural representation of value; the emotion paradox in the aging brain; perceptual foundations of bilingual acquisition in infancy; understanding disgust; and more.

The prevalence of obesity has dramatically increased over the last 25 years. In the United States, it is estimated that two-thirds of the population is either overweight or obese. This increase will undoubtedly continue to have profound medical, economic, and psychosocial consequences.

This volume comprises contributions from faculty and postdoctoral finalists of the 2011 New York Academy of Sciences Blavatnik Awards for Young Scientists.

This Annals volume includes scholarly summaries of scientific achievement by winners and finalists candidates of the 2011 Prix Galien USA awards for achievement in pharmaceutical science.

Aspergillosis, the leading fungal cause of mortality in immunocompromised patients, presents a serious worldwide challenge particularly in the face of increasing antifungal resistance.

Includes reviews on competition and the evolutionary dynamics of mutualism; rapid Hox gene evolution and the evolution of body plans; the evolutionary and conservation consequences of inbreeding - environment interactions; evolution and development of character displacement; applications of information theory to evolution; and gene duplications.