Bøger i Chemical Biology serien

Protein crystallography has become vital to further understanding the structure and function of many complex biological systems. In recent years, structure determination has progressed tremendously however the quality of crystals and data sets can prevent the best results from being obtained. With contributions from world leading researchers whose software are used worldwide, this book provides a coherent approach on how to handle difficult crystallographic data and how to assess its quality. The chapters will cover all key aspects of protein crystallography, from instrumentation and data processing through to model building. This book also addresses challenges that protein crystallographers will face such as dealing with data from microcrystals and multi protein complexes. This book is ideal for both academics and researchers in industry looking for a comprehensive guide to protein crystallography.

This book covers the biology of quorum sensing and quenching, potential sources of QQ enzymes and other inhibitors, as well as an overview of their mechanism and potential biotech applications.

The Chemical Biology of Carbon examines chemical biology open to carbon-containing natural metabolites that allow both retrospective and predictive behaviours of both biosynthetic and degradative metabolism in primary and secondary pathways ideal for medicinal chemists, chemical biologists and postgraduate students.

This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase.

The Chemical Biology of Nitrogen book provides a chemocentric approach to both the inorganic and organic chemical biology of nitrogen. Following an introduction to nitrogen trivalency the book progresses through the logic of inorganic nitrogen metabolism and organic nitrogen metabolites to nitrogen proteomics.

Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.

The overall aim of these books is to give scientists in academia and industry a comprehensive overview of the field of DNA damage and DNA repair and related human diseases.

This book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment.

An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.

Ideal for students and established biochemists, this book will cover new technologies for probe discovery, new probe modalities, the new field of probes for RNA targets and the mature field of kinase chemical probes.

This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.

Synthetic Glycomes aims to provide a comprehensive review of the current state of the synthetic glycome, synthetic strategies toward generating glycans with comprehensive structures, as well as the glycoarrays to unveil the glycan functions.

This book offers a fresh perspective on how computational tools can aid the chemical biology research community and drive new research.

This book serves as a practical reference for the current state of the art in high throughput screening, which remains a key part of early stage drug and tool compound discovery.

This book describes the development and application of glycoprotein and glycan synthesis technologies as tools for understanding and manipulating protein glycosylation.

This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

An essential resource for biochemists, biophysicists and chemical biologists, providing a complete understanding of the molecular machines of bioenergetics.

The overall aim of this book is to give scientists in academia and industry a comprehensive overview of the field of DNA damage and DNA repair and related human diseases.

With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich proteins.