Bøger i Drug Discovery serien

Shows how different parts of the drug discovery process have developed, with particular emphasis on quantitative aspects and possible future progress.

Drug Repurposing provides an ideal introduction to the field of drug repositioning and repurposing with contributions from world-renowned experts culminating in an excellent resource for any drug discovery or medicinal chemist.

An integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology in novel drug development.

A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.

This book, aimed at academics, industrialists and post-graduates, documents the latest research into computer aided drug design.

This unique book focuses on the currently 'hot topic' of Pharmaceutical Salts and Co-crystals. Combining both reports of the latest academic research and comprehensive overviews of basic principles, with more applied contributions from selected experts in industry.

This book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry by informing them about the breadth of the work carried out in chemical research and development departments. It is also of great value to academics wishing to advise students on the merits of careers in chemical development over discovery.

A practical guide for academic and industrial chemists to incorporating Green Chemistry principles into the drug discovery discipline and its everyday workflows with maximum benefit.

This book will review macrocycles in drug discovery and will be of interest to biochemists, pharmaceutical scientists and medicinal chemists working in industry or academia.

This volume describes the discovery and development history of the most promising drugs now in development for combating Alzheimer's disease.

This book will act as a primer for graduates and postgraduates interested in a career in drug discovery. It covers both synthetic technologies currently impacting medicinal chemistry and emerging areas.

The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.

An invaluable guide to successful practice in neglected tropical diseases (NTDs) and highlights best practice to guide the ongoing drug discovery effort.

This is the first comprehensive description of the discovery and therapeutic potential of polyamine drugs.

This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.

This is the first book to examine the future opportunities and challenges in the development of drugs which target kinases

The Medicinal Chemist's Guide to Solving ADMET Challenges presents state-of-the-art design strategies by a global group of experienced medicinal chemists and ADMET experts across academia and the pharmaceutical industry.

Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are vital to the signaling process and have been largely ignored in other works on signaling.

This thorough and up-to-date insight into predictive technologies considers what is on the horizon for safety prediction in human health.

This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.

Describes proteolytic enzymes and their biological function to aid drug discovery by detailing methods of production and assay of the enzymes.

This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.

This book provides up-to-date information on the use of transgenic mouse models in the study of neurodegenerative disorders. The editors have extensive knowledge and experience in this field and the book is aimed at undergraduates, postgraduates and academics.

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome.

A volume that will provide a mechanism-based approach to understanding Chinese medicine for both Western and Eastern scientists.

New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds. This timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.

Antibody-drug conjugates are a promising areas of anticancer drug discovery, conveying several advantages, including the ability to select likely responders, efficient delivery of cytotoxic agents and reduced toxicity. This book describes payloads used to date and novel payloads that may be used clinically in the future.

Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery.

Emerging Drugs and Targets for Alzheimer's Disease collects some of the most outstanding examples of new drugs currently in pharmaceutical development or new targets under the validation process that will reach the Alzheimer's drug market over the next few years as disease modifying drugs.

Written by medicinal chemists and ADMET scientists with a combined experience of over 300 years this aid to discovering drugs provides detailed coverage on absorption, distribution, metabolism, excretion and toxicology issues associated with new drugs.