Bøger i Neuromethods serien

The two Animal Models in Psychiatry volumes are loosely organized by subject. The second volume deals with affective and anxiety disorders, but also includes chapters on subjects not easily classified as either psychotic, or affective, or an- ety-related, such as aggression, mental retardation, and memory disorders.

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy.

Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors.

Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse.

Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain.

This volume provides in-depth descriptions and discussion of clinical trial designs based on novel data analysis of high-quality trials for 11 different neurological conditions in order to ultimately improve the quality of care in neurology.

This arrangement is based on what are ostensibly increasing levels of integrated activity of the nervous system and, therefore, increasing levels of behavioral integration.

This arrangement is based on what are ostensibly increasing levels of integrated activity of the nervous system and, therefore, increasing levels of behavioral integration.

Transcranial Magnetic Stimulation seeks to enable new and existing practitioners to learn and follow established TMS protocols.

Advances in methodologies and experimental models are pivotal to furthering our understanding of central nervous system (CNS) functions in mammals.

Continuing the research of the best-selling first edition, this second edition collects three more years of research in the ever-expanding study of the cell membrane.

A superb collection of time-tested, key techniques for investigating nervous system function, as well as the actions of drugs on the nervous system.

Combining insights of clinical investigators, this work aims to provide both critical reviews and detailed protocols for studying the medical role played by G proteins and cellular signalling in psychiatric and neurological disease.

This handbook contains state-of-the art reviews of techniques for analysing post-translational protein modifications. The contributors provide detailed and specific methods for studying protein phosphorylation/dephosphorylation, methylation, fatty-acylation, ADP-ribosylation, and glycosylation.

Most cells will survive removal from the natural mic- environment of their in vivo tissue and placement into a sterile culture dish under optimal conditions.

It goes without saying that the principles and techniques of molecular biology are having and will continue to have a major impact on investigations into nervous system structure and func tion.

In order to understand how the human brain functions, one must first understand its structure and mechanics. Part of a collection of methods offering proven techniques for productive work in this field, this volume deals with the area of neuropsychology.

Most cells will survive removal from the natural mic- environment of their in vivo tissue and placement into a sterile culture dish under optimal conditions.

This Neuromethods series book surveys new genetic techniques for generating genetically encoded activity sensors used to investigate neuronal activity. Each chapter covers a specific sensor and its utilization, with key description and implementation advice.

This book provides readers with up-to-date information on the basic principles of molecular imaging and its major applications in clinical neuroscience. It includes key tips and expert guidance to ensure successful research results.

This exploration of topics from immunohistochemistry for multiple neurochemicals covers a range of vital techniques from detecting expression levels of neurochemicals, to identifying polysynaptic pathways and recognizing functional changes in vivo.

Organized in sections on Physiology and Behavior, this Neuromethods series volume explores ideas and concepts behind the methods, tools, and tricks currently being utilized to decode the secrets of the brain of the small fruit fly, drosophila melanogaster.

Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience.

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy.

This volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.

This volume details methods for the analyses of specific lipid classes and lipidomics analyses of cells such as lymphocytes and oocytes.

Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques or combinations of techniques, applied to specific species in either healthy or abnormal brains.