Bøger af Shahin Asadi

Behcet's disease is characterized by recurrent oral ulcers, uveitis, oral ulcers, and skin lesions. Since vascular manifestations are common in this disease, it is considered as vasculitis. However, the dominant histological pathological symptoms in inflamed tissues include infiltration of lymphocytes, monocytes and in some cases, polynuclear leukocytes. Although small vessels are visible without microscopic changes in the wall. Thrombophilia or coagulation in small and large vessels is common, while arthritis is rare in this disease. In this regard, Behcet's disease is unique compared to other vasculitis. This disease is more prevalent in the countries along the Silk Road from Japan to the Mediterranean regions, so it prompted us to prioritize this disease in our studies. BCL2 and BAX genes are a group of signaling inducing and inhibiting genes that play a key role in the process of physiological cell death (apoptosis).

Today heart disease is very dangerous in humans. Because most heart disease is fatal to humans. Unfortunately, many human cardiovascular disease, caused by lack of proper development of heart muscle and heart cells in the fetus. Genes play a role in the development process of cardiovascular muscles that are important utero. In this book, the four main genes PEP,FNDC5,C2C12,PGC1¿ play an important role in the development of heart cells and cardiovascular muscles have studied.FNDC5 gene with another protein called Xuemei Proxy (PEP) is a 209 amino acid protein coding. These genes mainly in heart tissue, skeletal muscle and brain expressed. This study aimed to clarify the pattern of expression of this gene in mouse embryonic cells Heart cells taken. The mouse embryonic stem cells as a model for cardiac differentiation induced by ascorbic acid used and the pattern of expression of PEP at certain stages of differentiation were analyzed by Real-Time PCR technique. The results show a dramatic increase in PEP gene expression in the adult cardiomyocytes.

Today,neurological disorders,neuromuscular disorders are very important in creating. Including neurological disorders, including Lesch¿Nyhan syndrome (LNS). Lesch¿Nyhan syndrome (LNS) are a neuromuscular disorder that commonly causes a progressive neurodegenerative disease with X-linked inheritance, with the incidence in adulthood, the disease has three abnormal movements,cognitive disorders, psychological disorders known.Lesch¿Nyhan syndrome (LNS) is caused by genetic mutations,but also epigenetic factors are critical in inducing the disease. In this study we have analyzed 40 people. 20 Lesch¿Nyhan syndrome (LNS) and 20 control group. The gene HPRT1 analyzed in terms of genetic mutation made. In this study,people who have genetic mutation were targeted, with nervous disorders, Lesch¿Nyhan syndrome (LNS). In fact, of all people with Lesch¿Nyhan syndrome (LNS). 20 Lesch¿Nyhan syndrome (LNS) had a genetic mutation in the gene HPRT1 Lesch¿Nyhan syndrome (LNS). Any genetic mutations in the target genes control group, did not show.