Bøger af Siddhartha Mukherjee

Winner of the Guardian First Book Award 2011Winner of the Pulitzer Prize for Non-fiction 2011Shortlisted for the Wellcome Trust Book PrizeShortlisted for the Duff Cooper PrizeNow, as cancer becomes an ever more universal experience, the need to understand it, and its treatment, has never been more compelling. In this groundbreaking and award-winning account Siddhartha Mukherjee tells the fascinating story of our relationship with this disease. From brutal early surgical treatments, to Sidney Farber's hugely risky discovery of chemotherapy, to the author's treatment of his own patients, he reveals how far we have come in solving one of science's great mysteries and offers a fascinating glimpse of our future progress.

THE NEW YORK TIMES NUMBER ONE BESTSELLER BBC RADIO 4 BOOK OF THE WEEKThe Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.

**Longlisted for the Baillie Gifford Prize 2023**A NEW YORK TIMES, DAILY TELEGRAPH, ECONOMIST, MAIL ON SUNDAY and GUARDIAN BOOK OF THE YEAR 2022From the prize-winning author of The Emperor of All Maladies, The Song of the Cell tells the vivid, thrilling and suspenseful story of the fundamental unit of life.In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that alters both biology and medicine forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves, are built from these compartments. Hooke christens them 'cells'.The discovery of cells announced the birth of a new kind of medicine. A hip fracture, a cardiac arrest, Alzheimer's, AIDS, lung cancer - all could be re-conceived as the results of cells, or a cellular ecosystem, functioning abnormally. And all could be treated by therapeutic manipulations of cells. This revolution in cell biology is still in progress: it represents one of the most significant advances in science and medicine.Both panoramic and intimate, this is Siddhartha Mukherjee's most spectacular book yet.

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prizewinning author of The Emperor of All Maladiesa fascinating history of the gene and ';a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick' (Elle). "e;Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself."e; Ken BurnsDr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. Mukherjee expresses abstract intellectual ideas through emotional stories[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry (The Washington Post). Throughout, the story of Mukherjees own familywith its tragic and bewildering history of mental illnessreminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentationfrom Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we areand what our manipulation of those genes might mean for our future (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. The Gene is a book we all should read (USA TODAY).

"The story of the gene begins in earnest in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel, a monk working with pea plants, stumbles on the idea of a "unit of heredity." It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms postwar biology. It invades discourses concerning race and identity and provides startling answers to some of the most potent questions coursing through our political and cultural realms. It reorganizes our understanding of sexuality, gender identity, sexual orientation, temperament, choice, and free will, thus raising the most urgent questions affecting our personal realms. Above all, the story of the gene is driven by human ingenuity and obsessive minds -- from Gregor Mendel and Charles Darwin to Francis Crick, James Watson, and Rosalind Franklin to the thousands of scientists working today to understand the code of codes. Author of the Pulitzer Prize-winning bestseller The Emperor of All Maladies, Mukherjee draws on his scientific knowledge and research to describe the magisterial history of a scientific idea. Woven through The Gene is the story of Mukherjee's own family and its recurring pattern of schizophrenia, a haunting reminder that the science of genetics is not confined to the laboratory but is vitally relevant to everyday lives. The moral complexity of genetics reverberates even more urgently today as we learn to "read" and "write" the human genome -- unleashing the potential to change the fates and identities of our children and our children's children."--Book jacket, hardcover edition.

One of the world's premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine--and how understanding these principles can empower everyone.

Now in paperback, Siddhartha Mukherjee's instant New York Times-bestselling The Emperor of All Maladies, a 'magisterial' history of cancer--one of the New York Times Book Review's 10 Best Books of 2010. 'An extraordinary achievement." -The New Yorker "It's time to welcome a new star in the constellation of great writer-doctors. ' --Washington Post.