Bøger i Biological and Medical Physics, Biomedical Engineering serien

This book offers the readers an opportunity to acquire the concepts of artificial intelligence (AI) enabled sub-THz systems for novel applications in the biomedical field. The readers will also be inspired to contextualize these applications for solving real life problems such as non-invasive glucose monitoring systems, cancer detection and dental imaging. The introductory section of this book focuses on existing technologies for radio frequency and infrared sensing in biomedical applications, and their limited use in sensing applications, as well as the advantages of using THz technology in this context. This is followed by a detailed comparative analysis of THz electronics technology and other conventional electro optic THz setups highlighting the superior efficiency, affordability and portability of electronics-based THz systems. The book also discusses electronic sub-THz measurement systems for different biomedical applications. The chapters elucidate two major applications where sub-THz provides an edge over existing state of the art techniques used for non-invasive measurement of blood glucose levels and intraoperative assessment of tumor margins. There is a detailed articulation of an application of leveraging machine learning for measurement systems for non-invasive glucose concentration measurement. This helps the reader relate to the output in a more user-friendly format and understand the possible use cases in a more lucid manner. The book is intended to help the reader learn how to build tissue phantoms and characterize them at sub-THz frequencies in order to test the measurement systems. Towards the end of the book, a brief introduction to system automation for biomedical imaging is provided as well for quick analysis of the data. The book will empower the reader to understand and appreciate the immense possibilities of using electronic THz systems in the biomedical field, creating gateways for fueling further research in this area.

The book presents chitosan and chitosan-based nanocomposites and their extensive applications in medical science. Utilization of chitosan nanostructured composites in different biomedical applications is highlighted. The book is suitable to be used as reference/textbook for studying the biological aspects of chitosan hybrid materials and their efficacy in different therapeutic applications. The important features of the book are summarized as follows:Chitosan as an overviewKey biological aspects of chitosan-based nanocompositesSynthetic techniques for fabrication of chitosan nanocomposites for biomedical applicationsDesigning of chitosan-based smart materials for release of therapeuticsFabrication of nanostructured chitosan-based devices for diagnosis and sensing applicationsChitosan nanocomposites for regenerative applicationsMedicinal and therapeutic efficacy of chitosan-based hybrid materials.¿

This book highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs.Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes.This book discusses the advancements and innovations in the field of BME that improve the diagnosis and treatment of cancer. This book is focused on bioengineering approaches to improve targeted delivery for cancer therapeutics, which include particles, targeting moieties, and stimuli-responsive drug release mechanisms. This book is a useful resource for students, researchers, and professionals in BME and medicine.

This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.