Bøger i De Gruyter Textbook serien

This two volume book is an excellent introduction to this interdisciplinary area, lying on the interface between organic chemistry, biochemistry and medicine. The authors give a comprehensive overview of the field and outline the actual challenges in pharmaceutical science and industry. Volume 2 covers neurotransmitters, antihistamines, enzymatic inhibitors and nonsteroidal anti-inflammatory drugs.

The book is a comprehensive yet compressed entry-level introduction on single variable calculus, focusing on the concepts and applications of limits, continuity, derivative, defi nite integral, series, sequences and approximations. Chapters are arranged to outline the essence of each topic and to address learning diffi culties, making it suitable for students and lecturers in mathematics, physics and engineering. ContentsPrerequisites for calculusLimits and continuityThe derivativeApplications of the derivativeThe definite integralTechniques for integration and improper integralsApplications of the definite integralInfinite series, sequences, and approximations

This graduate textbook presents fundamentals, applications and evaluation of image segregation, unit description, feature measurement and pattern recognition. Analysis on textile, shape and motion are discussed and mathematical tools are employed extensively. Rich in examples and excises, it prepares electrical engineering and computer science students with knowledge and skills for further studies on image understanding.

This graduate textbook explains image reconstruction technologies based on region-based binocular and trinocular stereo vision, and object, pattern and relation matching. It further discusses principles and applications of multi-sensor fusion and content-based retrieval. Rich in examples and excises, the book concludes image engineering studies for electrical engineering and computer science students.

This graduate textbook explains image geometry, and elaborates on image enhancement in spatial and frequency domain, unconstrained and constrained restoration and restoration from projection, and discusses various coding technologies such as predictive coding and transform coding. Rich in examples and exercises, it prepares electrical engineering and computer science students for further studies on image analysis and understanding.

The aim of this book is to provide a concise but complete introduction to the main mathematical tools of nonlinear functional analysis, which are also used in the study of concrete problems in economics, engineering, and physics. This volume gathers the mathematical background needed in order to conduct research or to deal with theoretical problems and applications using the tools of nonlinear functional analysis. Contents Basic Topology Measure Theory Basic Functional Analysis Banach Spaces of Functions and Measures Convex Functions - Nonsmooth Analysis Nonlinear Analysis

Groups and Manifolds is an introductory, yet a complete self-contained course on mathematics of symmetry: group theory and differential geometry of symmetric spaces, with a variety of examples for physicists, touching briefly also on super-symmetric field theories. The core of the course is focused on the construction of simple Lie algebras, emphasizing the double interpretation of the ADE classification as applied to finite rotation groups and to simply laced simple Lie algebras. Unique features of this book are the full-fledged treatment of the exceptional Lie algebras and a rich collection of MATHEMATICA Notebooks implementing various group theoretical constructions.

This introduction into the multidisciplinary area of optofluidics offers the necessary foundations in photonics, polymer physics and process analytics to students, engineers and researchers to enter the field. All basic ingredients of a polymer-based platform as a foundation for quick and compact solutions for chemical, biological and medical sensing and manipulation are developed.

Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides.

While there is a plethora of excellent, but mostly "e;tell-it-all'' books on the subject, this one is intended to take a unique place in what today seems to be a still wide open niche for an introductory text on the basics of functional analysis to be taught within the existing constraints of the standard, for the United States, one-semester graduate curriculum (fifteen weeks with two seventy-five-minute lectures per week).a The book consists of seven chapters and an appendix taking the reader from the fundamentals of abstract spaces (metric, vector, normed vector, and inner product), through the basics of linear operators and functionals, the three fundamental principles (the Hahn-Banach Theorem, the Uniform Boundedness Principle, the Open Mapping Theorem and its equivalents: the Inverse Mapping and Closed Graph Theorems) with their numerous profound implications and certain interesting applications, to the elements of the duality and reflexivity theory. Chapter 1 outlines some necessary preliminaries, while the Appendix gives a concise discourse on the celebrated Axiom of Choice, its equivalents (the Hausdorff Maximal Principle, Zorn's Lemma, and Zermello's Well-Ordering Principle), and ordered sets.a Being designed as a text to be used in a classroom, the book constantly calls for the student's actively mastering the knowledge of the subject matter. It contains 112 Problems, which are indispensable for understanding and moving forward. Many important statements are given as problems, a lot of these are frequently referred to and used in the main body. There are also 376 Exercises throughout the text, including Chapter 1 and the Appendix, which require of the student to prove or verify a statement or an example, fill in necessary details in a proof, or provide an intermediate step or a counterexample. They are also an inherent part of the material. More difficult problems are marked with an asterisk, many problem and exercises being supplied with "e;existential'' hints.a The book is generous on Examples and contains numerous Remarks accompanying every definition and virtually each statement to discuss certain subtleties, raise questions on whether the converse assertions are true, whenever appropriate, or whether the conditions are essential.a a The prerequisites are set intentionally quite low, the students not being assumed to have taken graduate courses in real or complex analysis and general topology, to make the course accessible and attractive to a wider audience of STEM (science, technology, engineering, and mathematics) graduate students or advanced undergraduates with a solid background in calculus and linear algebra. With proper attention given to applications, plenty of examples, problems, and exercises, this well-designed text is ideal for a one-semester graduate course on the fundamentals of functional analysis for students in mathematics, physics, computer science, and engineering. ContentsPreliminariesMetric SpacesNormed Vector and Banach SpacesInner Product and Hilbert SpacesLinear Operators and FunctionalsThree Fundamental Principles of Linear Functional AnalysisDuality and ReflexivityThe Axiom of Choice and Equivalents

Basic Process Engineering Control is based on the extensive experience of theauthors in the field of industry, teaching and writing. The textbook showcasesmethods, problems, and tools used in this well-established fi eld of chemical engineering and goes beyond traditional process engineering by applying the same principles to biomedical processes, energy production, and management of environmental issues. Starting from the behavior of processes, Basic Process Engineering Control explains all determinations in "e;chemical systems"e; or "e;process systems"e;, such as the intricate inter dependency of the process stages, analyzing the hardware components of a control system, and the design of an appropriate control system for a process parameter or a whole process. Although mainly aimed at students and graduates, the book is equally interesting to chemical or process engineers in all industries or research and development centers. Readers will notice the similarity in approach from the system and control point of view between different fields, which might otherwise seem far from each other but share the same control philosophy.

Separation operations are crucial throughout the process industry with respect to energy consumption, contribution to investments and ability to achieve the desired product with the right specifications. Our main objective in creating thisgraduate level textbook is to present an overview of the fundamentals underlying the most frequently used industrial separation methods. We focus on their physical principles and the basic computation methods that are required to assess their technical and economical feasibility. The textbook is organized into three main parts. Separation processes for homogeneous mixtures are treated in the parts on equilibrium based molecular separations and rate-controlled molecular separations. The part on mechanical separation technology presents an overview of the most important techniques for heterogeneous mixture separation. Each chapter provides a condensed overview of the most commonly used equipment types. The textbook is concluded with a final chapter on the main considerations in selecting an appropriate separation process for a separation task. As the design of separation processes can only be learned by doing, we have included exercises at the end of each chapter. Short answers are given at the end of this book; detailed solutions are given in a separate solution manual.

L'ouvrage constitue une introduction au lexique francais de l'economie et de la gestion. Il s'adresse aux etudiants et professionnels non francophones disposant de bonnes connaissances de la langue francaise ainsi qu'aux enseignants de francais economique. Il presente un riche panorama de themes economiques, juridiques, sociaux et culturels et des exercices afin de familiariser le lecteur avec les notions de base de la science economique. This book serves as an introduction to the French language of economy and business economics. Aimed at non-Francophone students and professionals with a good knowledge of French and at teachers of business French, it discusses a vast array of economic, legal, social and cultural topics and contains numerous exercises. The volume is intended to familiarize its readers with the basics of economics.

Numerical analysis deals with the development and analysis of algorithms for scientific computing, and is in itself a very important part of mathematics, which has become more and more prevalent across the mathematical spectrum. This book is an introduction to numerical methods for solving linear and nonlinear systems of equations as well as ordinary and partial differential equations, and for approximating curves, functions, and integrals.

The mathematical fundamentals of molecular symmetry and group theory are comprehensibly described in this book. Applications are given in context of electronic and vibrational spectroscopy as well as chemical reactions following orbital symmetry rules. Exercises and examples compile and deepen the content in a lucid manner.

understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine¿. istry and medicine¿.

This book is written for engineering students and working professionals. Technical professionals are increasingly involved in IT issues, such as implementing IT systems, managing them, and taking part in requirements analysis/vendor selection. In this book, the basics of production planning systems (PPS) are covered, as well as their implementation in ERP-Systems like SAP. Readers also learn the basics of practical IT management and software creation through detailed, real-world examples. The book serves as a full 5 ECTS study module, which fits into any engineering curriculum. 150 multiple-choice quizzes, practical exercises and a text filled with experiential examples make it a convenient choice for selfstudy and for classroom use.

The book provides an excellent introduction to industrial biotechnology, addressing the applications of biomolecules and living systems in industrial manufacturing of various products. Each part of the book is devoted to a certain biotech sector, such as biofuels, food, chemicals, pharmaceuticals and materials. The book also covers the environmental aspects of industrial biotechnology and the principles of bio-based economy.

The book presents principles of molecular vibrational spectroscopy from the viewpoint of Raman, Raman optical activity and high excitation. The quantum mechanical basis, vibrational analysis, representation of point groups and its applications are discussed as well. With exercises, it is an essential text for graduates, lecturers, and also researchers.

This book is a valuable resource for achieving and promoting a culture of risk awareness and integrating risk management principles and practices into the educational environment. This integration is essential to ensure that students have the knowledge and skills to identify hazards, and assess and control risks in different contexts through the development and implementation of a risk management curriculum. Besides theoretical considerations and learning to ask the right questions at all times for the sake of critical thinking, effective risk management education also involves the use of case studies, simulations and other experiential learning tools to help students understand and apply risk management concepts in real-life situations. This approach helps students develop a questioning attitude and problem-solving skills, which are essential for effective risk management. Overall, the interface between risk management and education is essential to develop a generation of professionals who can effectively deal with risks in a variety of contexts. By integrating risk management principles and practices into the educational process, educational institutions can help ensure that their students are well prepared to meet the challenges of the modern world.

The book describes on an introductory level the designing of chemical processes and products so as to reduce or eliminate the use or production of toxic or hazards substances. It explains the code of conduct meant to reduce the environmental impact of any chemical process, whether at laboratory scale or industrial scale. The synonyms of Green Chemistry are the Sustainable Chemistry or the low-environmental-impact Chemistry.

Neural Networks is an integral part in machine learning and a known tool for controlling nonlinear processes. The area is under rapid development and provides a tool for modelling and controlling of advanced processes. This book provides a comprehensive overview for modelling, simulation, measurement and control strategies for reactive distillations using neural networks.

This highly regarded textbook provides a general introduction to solid state physics. It covers a wide range of physical phenomena occurring in solids and discusses fundamental concepts for describing them. Traditional themes are complimented by modern topics, like low dimensional systems, strongly correlated materials, nanoscale systems and non-crystalline solids, which are gaining increasing technical and scientific importance. Helpful for exam preparation are numerous exercises in all chapters.

Medical Microbiology is an excellent and easy-to-use textbook which explains the roles of microorganisms in human health and illness. Written in a clear and engaging manner, the book provides an overview of pathogenic organisms, their diagnosis and treatment tools as well as the molecular mechanisms of hostpathogen interactions and antimicrobial drug resistance.

Advanced data management has always been at the core of efficient database and information systems. Recent trends like big data and cloud computing have aggravated the need for sophisticated and flexible data storage and processing solutions.This book provides a comprehensive coverage of the principles of data management developed in the last decades with a focus on data structures and query languages. It treats a wealth of different data models and surveys the foundations of structuring, processing, storing and querying data according these models. Starting off with the topic of database design, it further discusses weaknesses of the relational data model, and then proceeds to convey the basics of graph data, tree-structured XML data, key-value pairs and nested, semi-structured JSON data, columnar and record-oriented data as well as object-oriented data. The final chapters round the book off with an analysis of fragmentation, replication and consistency strategies for data management in distributed databases as well as recommendations for handling polyglot persistence in multi-model databases and multi-database architectures. While primarily geared towards students of Master-level courses in Computer Science and related areas, this book may also be of benefit to practitioners looking for a reference book on data modeling and query processing. It provides both theoretical depth and a concise treatment of open source technologies currently on the market.

EPR spectroscopy is a versatile, nondestructive technique widely used in chemistry, biology, and physics. It detects molecules and materials with unpaired electrons making it a very selective technique that produces a wealth of information on such systems. Its high sensitivity makes it suitable in analyzing very small samples, single crystals, or reaction intermediates like radicals. This textbook takes a practical approach that introduces the basic concepts of EPR to sufficient detail to allow the reader to gain a basic knowledge of EPR and understand how experiments are carried out and how spectra are analyzed and interpreted. Many illustrative examples are included drawn from solid-state physics and bioinorganic chemistry. It is suitable as a short introduction for advanced undergraduate and beginning graduate students taking their first steps into EPR research.

This textbook is an elementary introduction to the basic principles of partial differential equations. With many illustrationsitintroduces PDEs on an elementary level, enabling the reader to understand what partial differential equations are, where they come from and how they can be solved. The intention is that the reader understands the basic principles which are valid for particular types of PDEs, and to acquire some classical methods to solve them, thus the authors restrict their considerations to fundamental types of equations and basic methods. Only basic facts from calculus and linear ordinary differential equations of first and second order are needed as a prerequisite. The book is addressed to students who intend to specialize in mathematics as well as to students of physics, engineering, and economics.

The fourth edition of this textbook has been thoroughly revised in order to reflect the central role which geodesy has achieved in the past ten years. The Global Geodetic Observing System established by the IAG utilizes a variety of techniques to determine the geometric shape of the earth and its kinematics, the variations of earth rotation, and the earth's gravity field. Space techniques play a fundamental role, with recent space missions also including gravity field recovery. Terrestrial techniques are important for regional and local applications, and for validating the results of the space missions. Global and regional reference systems are now well established and widely used. They also serve as a basis for geo-information systems. The analysis of the time variation of the geodetic products provides the link to other geosciences and contributes to proper modelling of geodynamic processes. The book follows the principal directions of geodesy, providing the theoretical background as well as the principles of measurement and evaluation methods. Selected examples of instruments illustrate the geodetic work. An extensive reference list supports further studies. The book is intended to serve as an introductory textbook for graduate students as well as a reference for scientists and engineers in the fields of geodesy, geophysics, surveying engineering and geomatics.

This textbook is devoted to the general asymptotic theory of statistical experiments. Local asymptotics for statistical models in the sense of local asymptotic (mixed) normality or local asymptotic quadraticity make up the core of the book. Numerous examples deal with classical independent and identically distributed models and with stochastic processes. The book can be read in different ways, according to possibly different mathematical preferences of the reader. One reader may focus on the statistical theory, and thus on the chapters about Gaussian shift models, mixed normal and quadratic models, and on local asymptotics where the limit model is a Gaussian shift or a mixed normal or a quadratic experiment (LAN, LAMN, LAQ). Another reader may prefer an introduction to stochastic process models where given statistical results apply, and thus concentrate on subsections or chapters on likelihood ratio processes and some diffusion type models where LAN, LAMN or LAQ occurs. Finally, readers might put together both aspects. The book is suitable for graduate students starting to work in statistics of stochastic processes, as well as for researchers interested in a precise introduction to this area.