Bøger i Developments in Molecular and Cellular Biochemistry serien

The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II.

Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands

Twenty years have elapsed since cytoplasmic proteins exhibiting high-affinity binding of long-chain fatty acids were first identified (Ockner et al., Science 177:56-58, 1972). These cellular fatty acid-binding proteins (FABPs) are now well established to comprise a ligand-defined group of macromolecules belonging to a family of cytoplasmic lipid binding proteins. Unique features of the FABPs are the existence of distinct types of FABP and that these are found in a variety of tissues in remarkable abundance, with some cells expressing more than one type. The physiological significance of the FABPs has only partly been elucidated. By increasing the cytoplasmic solubilization of fatty acids, the cellular FABPs are considered to function primarily in intracellular fatty acid transport, but may also be assigned important regulatory roles in cellular lipid homeostasis as well as in the modulation of cell growth and differentiation. The broad interests in cellular FABPs has led to the organization of the 1st International Workshop on Fatty Acid-Binding Protein, held in Maastricht, the Netherlands, in 1989. Prompted by the success of the first meeting, the 2nd International Workshop on Fatty-Acid-Binding Proteins, which was held again in Maastricht, on August 31 and September 1, 1992, brought together scientific scpecialists in the field of FABP research for two days of intensive and fruitful discussion. This volume is a collection of selected papers from this conference, and thus provides the state-of-the-art knowledge of cellular FABPs. The contributors to this issue represent pioneering as well as new investigators, and also reflect the multidisciplinary nature of research in this exciting and rapidly progressing field.

The editors of this volume invited all authors who are most active at present in experimental research on creatine kinases to summarize their work and make the information easily available to a wider scientific audience, especially to young investigators who are entering this field.

It is well established that cellular lipid binding proteins serve central roles in cellular lipid uptake and metabolism.

Collects articles from two related meetings - the first was held in Buenos Aires, Argentina on April 11-12, 1997 and the second meeting took place in Stara Lesna located in the High Tatras Mountains of the Slovak Republic on June 27-30, 1997.

A variety of metabolic processes are known to be intimately involved in the maintenance of cellular structure and function. Special emphasis has been laid on understanding heart function and metabolism in health and disease in general, and cardiac hypertrophy, heart failure, and ischemic heart disease in particular.

This volume explores all aspects of vascular biochemistry and includes chapters that provide an understanding of vascular function with descriptions of tissue components present in the vascular wall as well as an exploration of the hemodynamic and metabolic activities associated with this function.

The breadth of modern biology is characterized by a comprehension of phenomena at many levels of organization. It is when all these levels can be discussed together that a sense of true achievement begins to be felt.

The focus of this special issue of Molecular and Cellular Biochemistry is underlying mechanisms that regulate cardiac growth.