Bøger i IPEM-IOP Series in Physics and Engineering in Medicine and Biology serien

A practical book that works with both inductive and deductive instructional methods. We have developed a concise, yet conceptually rich, start for learners that should feel friendly and interactive in nature.

The relentless pace of innovation in biomedical imaging has provided modern researchers with an unprecedented number of techniques and tools to choose from. While the development of new imaging techniques is vital for ongoing progress in the life sciences, it is challenging for researchers to keep pace. Imaging Modalities for Biological and Preclinical Research is designed to provide a comprehensive overview of currently available biological and preclinical imaging methods, including their benefits and limitations. Experts in the field guide the reader through both the physical principles and biomedical applications of each imaging modality, including description of typical setups and sample preparation.Volume 1 focuses on ex-vivo imaging. It covers all available advanced and basic light and fluorescence microscopy modalities, X-ray, electron, atomic force and helium ion microscopy, dynamic techniques such as fluorescence recovery after photobleaching as well as spectroscopic techniques such as coherent Raman imaging or mass spectrometry imaging.Key featuresProvides an overview of fast-evolving ex-vivo imaging technologies.Bridges biological and preclinical imaging.Written by imaging specialists with extensive expertise in their respective fields.

This book is intended to facilitate the testing of dynamic imaging systems to ensure safety of the systems. The aim is to discuss methods and techniques that may be used to commission and perform quality control (QC) measurements of dynamic x-ray imaging systems; the primary function of which is real time imaging to provide visualization of dynamic anatomical and other processes as they occur.Since dynamic imaging equipment is used for a wide range of clinical applications, the report includes a general description of the characteristics and operational aspects to assist the medical physicist with clinical setup and performance evaluation strategies. The automatic close rate control (ADRC) plays a significant role in determining the balance between patient dose and image quality, therefore the function and evaluation of ADRC plays a significant role in determining the balance between patient dose and image quality, therefore the function and evaluation of ADRC devices is discussed extensively.Key FeaturesDiscuss methods and techniques that may be used to commission and perform quality control (QC) measurements of dynamic X-ray imaging systems.Includes a general description of the characteristics and operational aspects to assist the medical physicist with clinical setup and performance evaluation strategies.Function and evaluation of ADRC devices is discussed extensively.

This volume presents the applications of Nanotechnology to different fields of dentistry. Recognized dental specialities such as orthodontics, endodontics and prosthodontics have been covered in addition to general dentistry applications of nanotechnology. The book, in a comprehensive fashion, delves into such technologies as drug nanocarriers, nanomaterials, implants and other nanoparticle applications related to dentistry, and shows how these, in turn, will enhance therapeutic effects against dental bacteria and erosion. This book not only presents the current trends in dental therapies but also presents the current research trends and potential applications. A bottom-up approach has been mostly adopted to suit the need of a wide audience including novice researchers and post graduate students.Key Features: Each chapter includes brief review in the initial paragraphs followed by recent trendsContent level designed to suit the needs of technicians in addition to novice researchersThere is necessary minimum overlap from available literatureA number of the chapter authors are highly esteemed researchers in their prospective fieldsUnique coverage of such topics as nanorobotic local anesthetics, neurotoxticity, nano endodontic sealers, orthodontic nanorobots, nanodiagnostics

The Book will address the advances of next-generation medical imaging techniques coupled with nanomedicine, for image guidance, for the tumor detection, tumor tissue characterization, monitoring of drug targeting, pre and post therapy monitoring of solid tumors.

Discussion of various IOT based systems for classification and design strategy of biomedical systems are provided in the book. This book can serve as a pillar for the IOT application in biomedical systems understanding.

This edited volume highlights different oral diagnostic tools and techniques from a physicist's viewpoint, with chapters written by a range of academicians and practitioners from dentistry and physics.

Applying the general deterministic approach of systems computational biology, the monograph considers questions related to the biomechanics of the human urinary bladder in conjunction with the peripheral and central nervous systems. The step-by-step development of mathematical models of separate structural elements and their assembly into a unique self-regulatory system offers, for the first time, a holistic overview and allows the investigation of the dynamics of the lower urinary tract system at its hierarchical levels. This book provides a coherent description and explanation for intertwined intracellular pathways in terms of spatiotemporal, whole body, tractable representations which are supported by numerous computational simulations.Key FeaturesIt reconstructs accurately the cytoarchitecture and morphofunctional relationships between the elements of the central nervous (brain) and genitourinary (urinary bladder system).Offers for the first time a both quantitative and qualitative, assessment of the neurohormonal and mechanobiological processes involved in the process.Provides a comprehensive description for intertwined regulatory pathways in terms of spatiotemporal dynamic representations.Encourages the reader to develop and apply a unique holistic approach to solving complex biomedical problems in the area of growth and remodeling of the urinary bladder through application of modern methods of computational biology.

This book focuses on major trends and challenges in the area of diagnosing lung and kidney cancer using artificial intelligence tools. It presents work aimed to identify new techniques and their use in biomedical analysis.

This book focuses on major trends and challenges in the area of diagnosing lung and kidney cancer using artificial intelligence tools. It presents work aimed to identify new techniques and their use in biomedical analysis.

This book describes the theoretical principals and provides practical advice on the performance of QA measurements and discusses important performance parameters and the results that may be expected.

Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, as well as the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform.The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions.Key FeaturesComputational and experimental fluid dynamics principles have been used to explore the modelling of diseased blood vesselsPrinciples of fluid dynamics and tissue engineering are used to propose innovative designs of bioreactors for blood vessel regenerationOffers experimental analytical studies of blood flow in vessels with pathological conditionsControlling aspects of various parameters while developing blood-vessel bioreactors and organoid models are presented critically, and optimization techniques for these parameters are also provided

This book covers the fundamental knowledge required to implement the IGRT techniques in abdominal cancer treatment with detailed operational procedures involved, and also provides an overview of emerging techniques for future application. This is an ideal text for Radiation oncologists, medical physicists, dosimetrists, and radiation therapists.

Design and Shielding of Radiotherapy Treatment Facilities provides readers with a single point of reference for protection advice to the construction and modification of radiotherapy facilities. The book assembles a faculty of national and international experts on all modalities including megavoltage and kilovoltage photons, brachytherapy and high-energy particles, and on conventional and Monte Carlo shielding calculations. This book is a comprehensive reference for qualified experts and radiation-shielding designers in radiation physics and also useful to anyone involved in the design of radiotherapy facilities.

Magnetic Nanoparticles for Medical Diagnostics aims to encourage members of the medical profession to join experts from other fields of research in exploring the unique physical properties of magnetic nanoparticles for medical applications.

A learning and revision resource for those studying for radiology fellowship examinations. Updated with more than 50 new questions, and a new chapter on functional and molecular imaging.

Biomechanical Modeling of the Cardiovascular System brings together the challenges and experiences of academic scientists, leading engineers, industry researchers and students to enable them to analyse results of all aspects of biomechanics and biomedical engineering. It also provides a springboard to discuss the practical challenges and to propose solutions on this complex subject.

Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature and reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. This book is a compilation of research development lead by expert researchers and it establishes a single reference module. It addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field.

This book is essential reading for medical physicists in radiation protection, diagnostic radiology and nuclear medicine, as well as radiographers and technologists, due to changes in global dosimetry requirements. Additionally, it presents guidelines for medical physicists and others using radiation.

This book reflects the broad advances that have been made in the field of medical dosimetry and medical radiation protection, and it provides information about the practical use of new information in radiation dose management of pregnant patients, pregnant staff and paediatric patients in diagnostic and interventional radiology.

This book covers the principles, advantages and potential pitfalls that occur in proton therapy, especially its radiobiological modelling applications. It is intended to educate, inform and stimulate further research questions by blending the relevant physics, biology and medical aspects of this multidisciplinary subject.

Anthropomorphic Phantoms in Image Quality and Patient Dose Optimization: A EUTEMPE Network book is invaluable for medical physicists and biomedical engineers, and it is unique in its form and content. The book focuses on the practical applications of anthropomorphic phantoms for research and educational purposes, and includes tutorials and self-training examples.

This book provides a review of the history and technologies in the development of computational small animal models, with a focus on their application in preclinical imaging, radiation therapy and dosimetry calculations. It provides an overview of model design of computational models, identification of anatomical data, the tools used for solving problems and animal model application in preclinical research.

Principles of Biophotonics, volume two describes detection and statistical representation of optical fields. Beginning by placing the visible spectrum in the context of the electromagnetic frequency range, this presentation stresses how thin of a sliver is normally called the optical spectrum. In addition to describing properties of light with technical accuracy, the most common radiometric quantities are introduced, and conversion to photon-based quantities is explicitly presented. For completeness, an analogy to the photometric quantities is also made, and the three fundamental mechanisms for generating light, blackbody radiation, fluorescence and laser emission, are covered. Each chapter contains a set of practice problems and additional references, and this book aims to build the foundation for further study in subsequent volumes.