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As robots improve in efficiency and intelligence, there is a growing need to develop more efficient, accurate and powerful sensors in accordance with the tasks to be robotized. This has led to a great increase in the study and development of different kinds of sensor devices and perception systems over the last ten years. Applications that differ from the industrial ones are often more demanding in sensorics since the environment is not usually so well structured. Spatial and agricultural applications are examples of situations where the environment is unknown or variable. Therefore, the work to be done by a robot cannot be strictly programmed and there must be an interactive communication with the environment. It cannot be denied that evolution and development in robotics are closely related to the advances made in sensorics. The first vision and force sensors utilizing discrete components resulted in a very low resolution and poor accuracy. However, progress in VLSI, imaging devices and other technologies have led to the development of more efficient sensor and perception systems which are able to supply the necessary data to robots.

These proceedings contain lectures presented at the NATO-NSF-ARO sponsored Advanced Study I~stitute on "Computer Aided Analysis and Optimization of Mechanical System Dynamics" held in Iowa City, Iowa, 1-12 August, 1983. Lectures were presented by free world leaders in the field of machine dynamics and optimization. Participants in the Institute were specialists from throughout NATO, many of whom presented contributed papers during the Institute and all of whom participated actively in discussions on technical aspects of the subject. The proceedings are organized into five parts, each addressing a technical aspect of the field of computational methods in dynamic analysis and design of mechanical systems. The introductory paper presented first in the text outlines some of the numerous technical considerations that must be given to organizing effective and efficient computational methods and computer codes to serve engineers in dynamic analysis and design of mechanical systems. Two substantially different approaches to the field are identified in this introduction and are given attention throughout the text. The first and most classical approach uses a minimal set of Lagrangian generalized coordinates to formulate equations of motion with a small number of constraints. The second method uses a maximal set of cartesian coordinates and leads to a large number of differential and algebraic constraint equations of rather simple form. These fundamentally different approaches and associated methods of symbolic computation, numerical integration, and use of computer graphics are addressed throughout the proceedings.

1. Chromatographic Processes.- Modelling Equilibrium and Kinetics in Chromatographic Processes.- Theory of Linear and Nonlinear Chromatography.- Hydrodynamics of Chromatographic Columns.- Cyclic Fixed Bed Sorption Processes for Bioseparations - Design Aspects.- Separations by Continuous Annular Chromatography.- Gradient Elution Chromatography.- Rate Processes in Supercritical Fluid Desorption and Extraction.- 2. Membrane Processes.- Fundamentals of Membrane Separation Processes.- Pressure-Driven Membrane Processes.- Ellectrically-Driven Membrane Processes.- Novel Membranes - Formation and Process Applications.- Cell Harvesting Using Cross-Flow Microfiltration.- Recovery of Intracellular Products.- Pervaporation in Biotechnology.- 3. Affinity Processes.- Affinity Chromatography: Principles and Applications.- Theory of Affinity Chromatography.- Affinity Partitioning.- Prediction of Partition Coefficients for Peptides in Aqueous Two-Phase Systems.- Membrane Affinity Filtration.- 4. Design of Separation Media.- Affinity Chromatography: Design of Biospecific Chromatographic Materials.- Membranes for Bioprocessing: Design Considerations.- 5. Scale-Up, Optimization and Process Integration.- Operating Modes, Scale-up and Optimization of Chromatographic Processes.- Scale-up and Optimization of Membrane Processes.- Simultaneous Reaction and Chromatography.- Membrane bioreactors.- Recombinant Human Tissue-Plasminogen Activator: Biochemistry, Pharmacology, and Process Development.- List of Contributors and Participants.

Theoretical Background.- Genetic Approaches to Common Diseases.- A Candidate Gene Approach to the Genetics of Normal Lipid Variation: DNA Association Studies and Genotype by Environment Interaction.- Molecular Genetics Approach to Polygenic Disease - Initial Results from Atherosclerosis Research.- Diabetes.- Facilitative Glucose Transporters: Regulation and Possible Role in NIDDM.- Molecular Genetic Approach to Polygenic Disease: Dependent Diabetes Mellitus (NIDDM).- Lipids.- HDL and Reverse Transport of Cholesterol: Insights from Mutants.- Apolipoprotein E Polymorphisms and the Genetic Heterogeneity of Familial Dysbetalipoproteinaemia.- Abnormalities of Apolipoprotein B Metabolism in the Lipid Clinic.- Genetic Variation at the ApoA-I, CIII, A-IV Gene Complex: A Critical Review of the Associations between the Pst1 and Sst1 RFLPs at this Locus with Lipid Disorders.- The Molecular Basis of the Chylomicronemia Syndrome.- Lipoprotein Lipase Gene Variants in Subjects with Hypertriglyceridaemia and Coronary Atherosclerosis.- Atherosclerosis.- Atherosclerosis: The Genetic Analysis of a Multi-Factorial Disease.- RFLP Markers of Familial Coronary Heart Disease.- DNA Polymorphisms as Disease Markers.- Participants.

Terminology in Biological Rhythms; M.A. Ali, et al. Introduction to the Analysis of Periodic Phenomena; P. Legendre, P. Dutilleul. Biological Rhythms; M.P. Gerkema. Behavior and Rhythms in Fishes; D.L.G. Noakes. Ultradian Rhythms in Fishes; R.C. Peters, R.J. Veeneklaas. Tidally-Synchronised Behavior in Marine Fishes; R.N. Gibson. Lunar and Semi-Lunar Rhythms in Fishes; J.F. Leatherland, et al. Circadian Basis for Neuroendocrine Regulation; A.H. Meier. Sleep, Inactivity, and Circadian Rhythms in Fish; S. Reebs. Feeding-Entrained Circadian Rhythms in Fishes; R.E. Spieler. Melatonin Rhythms in the Pineal Organ of Fishes and its Effects; A. Zachmann, et al. Regulation of the Rhythmic Melatonin Secretion by Fish Pineal Photoreceptor Cells; J. Falcón, et al. The Rainbow Trout Pineal Organ; W.A. Gern, et al. 6 additional articles. Index.

Introduction. Phase Transitions in the Early Universe and Defect Formation; T.W.B. Kibble. The Topological Classification of Defects; M. Kleman. Introduction to Growth Kinetics Problems; G.F. Mazenko. Dynamics of Cosmological Phase Transitions: What Can We Learn from Condensed Matter Physics? N. Goldenfeld. Topological Defects and Phase Ordering Dynamics; A.J. Bray. The Production of Strings and Monopoles at Phase Transitions; R.J Rivers, T.S. Evans. Geometry of Defect Scattering; N.S. Manton. Theory of Fluctuating Nonholonomic Fields and Applications: Statistical Mechanics of Vortices and Defects and New Physical Laws in Spaces with Curvature and Torsion; H. Kleinert. String Network Evolution; E.P.S. Shellard. Global Field Dynamics and Cosmological Structure Formation; R. Durrer. Electroweak Baryogenesis; N.G. Turok. Dynamics of Cosmic Strings and Other Brane Models; B. Carter. Cosmological Experiments in Superfluids and Superconductors; W. Zurek. Cosmological Experiments in Liquid 4He-Problems and Prospects; P.C. Hendry et al. Index.

Present and Future of Nuclear Physics; Introductory Lecture. Cluster Decay, Fission and Fusion: Cluster Radioactivity; P.B. Price. Recent Advances in Cluster Radioactivities; D.N. Poenaru, W. Greiner. Heavy Elements: Multinucleon Transfer Reactions-An Alternative Path to Heavy Element Synthesis; M.T. Magda. Microscopic and Semi-microscopic Approach to the Properties of Transactinide Nuclei; L. Bitaud, et al. Nuclear Structure: On the Origin of Rotations and Vibrations in Atomic Nuclei; J.P. Draayer, et al. Particle-rotor Model Description of Deformed Nuclei; A. Covello, et al. Weak Interaction and Double Beta Decay: Nuclear Aspects of Double Beta Decay; S. Stoica. A New Look to the Nuclear Structure Calculations of the PNC Cases in A=1821 Nuclei; M. Horoi. Nuclear Astrophysics: Recent Topics from Nuclear Reactions in the Energies Ranging from keV to GeV; K. Kubo. Heavy Ion Collisions: Processes in Peripheral Ultrarelativistic Heavy Ion Collisions; M. Greiner, et al. Miscellaneous Topics: Gamma and Meson Production by Cherenkovlike Effects in Nuclear Media; W. Stocker, D.B. Ion. 58 additional articles. Index.

Progress in Genetic Engineering of the Pyridine and Propane Alkaloid Biosynthetic Pathways of Solanaceous Plants; R.J. Robins, et al. Molecular Genetic Techniques Applied the Analysis of Enzymes of Alkaloid Biosynthesis; T.M. Kutchan. Polyketide Biosynthesis; W.R. Strohl, R. Plater. The Biologists Palatte; N. Courtney-Gutterson. Engineering Altered Glucosinolate Biosynthesis by Two Alternative Strategies; R.K. Ibrahim, et al. Genetic Manipulation of Lignin and Phenylpropanoid Compounds Involved in Interactions with Microorganisms; R.A. Dixon, et al. The Genetic Origins of Biosynthesis and Light-Responsive Control of the Chemical UV Screen of Land Plants; R. Jorgensen. Genetic Control of Monterpene Biosynthesis in Mints; R. Corteau, J. Gershenzon. Genetic Manipulation of Terpenoid Phytoalexins in Gossypium; A.A. Bell. Analysis of Secondary Metabolism in Arabidopsis; C. Chapple. Polyphenol Oxidase; J.C. Steffens, et al. Genetic Regulation of Lignin Biosynthesis and the Potential Modification of Wood by Genetic Engineering in Loblolly Pine; S. Ronald, et al. Index.

Nuclear Collisions and Structure: Descriptions of Heavy Ion Collisions at Intermediate Energies; E. Lehman. Boltzman Master Equation Theory of Nuclear Reactions; M. Cavinato, et al. Formation and Decay of Hot Nuclei; B. Tamain. Statistical and Dynamical Aspects of Hot Nucleus DeExcitation; M. Gui et, al. Atomic Collisions: New Means and Objectives in the X and XUv Spectroscopy and Imagery; Y. Cauchois. Collisions of Molecules with Clusters; J. Jellinek, Z.B. Guvenc. Theory of Slow Atomic Collisions; F. Masnou-Seeuws. RMatrix Calculation of Multichannel Quantum Defect Parameters in Heavy Alkaline Earth Atoms; M. Aymar. New Phenomena at High Energy Collisions: Renaissance of Interest in Cosmic Rays; H. Rebel. The Sharp Lepton Problem and the C(Q0) Scenario; J.J. Griffin. Electromagnetic and Mesonic Cherenkov Effects in Nuclear Media; W. Stocker, D.B. Ion. 16 additional articles. Index.

Polyatomic Ion Dissociative Recombination; D.R. Bates. Recent Developments and Perspectives in the Treatment of Dissociative Recombination and Related Processes; A. Guisti-Suzor, et al. Electron-Ion Continuum-Continuum Mixing in Dissociative Recombination; S.L. Guberman. Recent Merged Beam Investigations of Hydrogen Molecular Ion Recombination; J.B.A. Mitchell, et al. Recent Flowing Afterglow Measurements; B.R. Rowe. Recombination of Cluster Ions; R. Johnsen. Associative Ionization of Hydrogen; F. Brouillard, X. Urbain. Resonant Theory of Dissociative Attachment; I.I. Fabrikant. Dissociative Recombination in Planetary Ionospheres; J.L. Fox. Chemistry of Supernova 1987a; A. Dalgarno. Factoring Sequences of Dynamic Processes in a Single Collision; F.H. Mies. Dissociative Electron Attachment to TransitionMetal Hydrides; T.M. Miller, et al. Electron Impact Dissociative Excitation of Molecular Ions; A.E. Orel. 17 additional articles. Index.

tRNA and AminoacyltRNA Synthetases: Charging of RNA Microhelices and Decoding Genetic Information; P. Schimmel. rRNA and mRNA: Regulation, Processing, and Assembly: Genetic Approaches to the Study of Eukaryotic Ribosomes; J.R. Warner, et al. Translational Initiation and Termination: Mechanisms of Translational Initiation and Repression in Prokaryotes; D.E. Draper. The Elongation Process: Sites, Factors, Nascent Chain: The Allosteric ThreeSite Model and the Mechanism of Action of Both Elongation Factors EFTu and EFG; K.H. Nierhaus, et al. Accuracy in Translation: Mutants of tRNA, Ribosomes, and mRNA Affecting Frameshifting, Hopping, or Stop Codon Read-Through; J.F. Atkins, et al. Quaternary Structure, Functional Centers, and Domains in the Ribosome. Translation in Cell Organelles. The Translational Apparatus and Evolution. 64 additional articles. Index.

Outstanding Problems in Cancer Risk Assessments: Pharmacodynamic Models for Cancer Risk Assessment; S.H. Moolgavkar. Oncogenes: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogene Assessment and Human Cancer; D.A. Spandidos, M.L.M. Anderson. Transgenics: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogenic Transgenic Mice in the Study of Carcinogenesis; C.H. Ahn, W.C. Choi. Case Studies: Review of Methylene Chloride Cancer Risk Assessment: Cancer Dose-Response Modeling and Methylene Chloride; G. Charnley. Case Studies: Review of Benzene Cancer Risk Assessment: Risk Assessments for Benzene-Induced Leukemia; K.S. Crump. Concluding Remarks: Findings and Recommendations; C. Zervos. Index.

Compartmentation in Aromatic Metabolism; F. Hrazdina. Immunolocalization of Flavonoid Conjugates and their Enzymes; R.K. Ibrahim. General Phenylpropanoid Metalbolism; C.J. Douglas, et al. Molecular Biology of Stress-Induced Phenylpropanoid and Isoflavonoid Biosynthesis in Alfalfa; R.A. Dixon, et al. Biosynthesis and Metabolism of Isoflavones and Pterocarpan Phytoalexins in Chickpea, Soybean, and Phytopathogenic Fungi; W. Barz, R. Welle. Flavonoid Synthesis in Petunia Hybrida; A.G.M. Gerats, C. Martin. Flavonoids; D.A. Phillips. Flavonoid Sulfation; L. Varin. Synthesis and Base-Catalyzed Transformations of Proanthocyanidins; D. Ferreira, et al. Enzymatic Synthesis of Gallotanins and Related Compounds G.G. Gross. Enantioselective Separations in Phytochemsitry; L.B. Davin, et al. The Phytochemical Society of North America; S.A. Brown. Index.

Studies of Reovirus Pathogenesis Reveal Potential Sites for Antiviral Intervention.- Drugs as Molecular Tools.- Genetically Engineered Bacteria to Identify and Produce Antiviral Agents.- Antiviral Agents from Novel Marine and Terrestrial Sources.- Virus Receptors: The Achilles' Heel of Human Rhinoviruses.- Therapeutic Strategies Employing CD4, The HIV Receptor.- Molecular Characterization of HIV-2 (ROD) Protease following PCR Cloning from Virus Infected H9 Cells.- A Novel, Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase (Review).- Catalytic Antisense RNA (Ribozymes): Their Potential and Use as Anti-HIV-1 Therapeutic Agents.- Therapies for Hepatitis B Virus: Current Status and Future Possiblities.- A Preliminary Report of a Controlled Study of Thymosin Alpha-1 in the Woodchuck Model of Hepadnavirus Infection.- Delta Virus as a Vector for the Delivery of Biologically Active RNAs: Possibly a Ribozyme Specific for Chronic Hepatitis B Virus Infection.- Inhibition of Herpes Simplex Virus Ribonucleotide Reductase by Synthetic Nonapeptides: A Potential Antiviral Therapy.- Antiviral Effects of Herpes Simplex Virus Specific Anti-Sense Nucleic Acids.- Heterogeneity of a Herpes Simplex Virus Clinical Isolate Exhibiting Resistance to Acyclovir and Foscarnet.- Cellular Metabolism and Enzymatic Phosphorylation of 9-(2-Phosphonylmethoxyethyl) Guanine (PMEG), a Potential Antiviral Agent.- Effect of Herpes Simplex Virus Type 1 Infection on Cytokine Gene Expression in Activated Murine Peritoneal Macrophages.- Procedure for Evaluation of Neutralizing Antibody to Cytomegalovirus in Commercial Intravenous Gamma Globulin Preparations.- Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation ELISA.- Emerging Trends in the Rapid Detection of Viruses.- DNA Probes for Viral Diagnosis.- Contributors.

Histopathology of Bronchial Asthma; P.K. Jeffery. Airway Neuropeptides; P. Barnes. Potential Role of Mast Cell Proteases in Asthma; J. Nadel. Human Mast Cells, Basophils, and their Mediators; V. Casolaro, et al. Platelets and Asthma; J. Morley, et al. Leukotrienes and Asthma; J. Rokach, et al. Plasma Exudation in Asthma and its Pharmacological Control; C. Persson. Synthesis and Regulation of IgE in Asthma; G. Del Prete. Osmotic and Ionic Factors in Bronchial Responsiveness; S. Bianco, et al. Airway Responsiveness, Late-Phase Response, and Inflammation in Allergic Asthma; V. Brusasco, et al. Injury and Repair of the Airway Epithelium in Asthma; S. Rennard, et al. Bronchial Asthma and Pulmonary Gas Exchange; R.R. Rodriguez. Asthma Management; A. Tattersfield. The National Asthma Education Program; S. Hurd. Management of Asthmatic Children; K.F. Kerrebijn. 12 additional articles. Index.

Introduction: Atomic Physics and Nuclear Properties; J. Bauche. Atomic Methods in Nuclear Spectroscopy: Progress in Atomic Physics Experiments on Nuclear Properties; R. Neugart. Single Particle Aspects: Single Particle Response Function; S. Gales. Multiphonon States: Low-Energy Multiphonon States in Deformed Nuclei; R. Piepenbring. Shapes and Coexistence: Algebraic Approaches to Nuclear Structure; R.F. Casten. Octupoles: Reflection-Asymmetric Shapes in Atomic Nuclei; W. Nazarewicz. Superdeformation: Microscopic Description of Superdeformation at Low Spin; R. Bonche, et al. Exotic Nuclei: Search for New Radioactivities at the Proton-Drip Line; F. Pougheon, et al. Chaos: Quantum Chaos and Low-Energy Nuclear Spectroscopy; M.J. Giannoni. Experimental Techniques: Nuclear Moments by Orientation Methods; H. Postma. 35 additional articles. Index.

Photophysics: The Nature of the Light Field in Biological Media B.C. Wilson. Photochemistry: Quantum Yield of a Photochemical Reaction; R.H. Potter, et al. Photosensitization: Photosensitization: Reaction Pathways; J.E. van Lier. Photosynthesis: Near Infra-Red Flash Absorption: A Tool for Studying Photosynthesis; P. Mathis, et al. UV Effects: Response to Ultraviolet Radiation in a Simple Eukaryote; (Yeast): Genetic Control and Biological Consequences; D. Averbeck, et al. Environmental Photobiology: Isolation and Biological Consequences of Plant Derived Phototoxins; J.T. Arnason, et al. Vision: Visual Pigments: Absorbance Spectra and Photoproducts; J.K. Bowmaker. Photomorphogenesis: Photomorphogenesis Responses to UV Light: Involvement of Phytochrome and Photoreceptors; B. Lercari. Photomovement: Photomovement; W. Nultsch, et al. Bioluminescence: Bioluminescence: Biochemistry for Fun and Profit; J. Lee. Photomedicine: Photomedicine: Photodermatology B. Johnson. Other Experiments: Experiments Reprinted from The Science of Photobiology, First Edition; K.C. Smith. Appendix: Units of Measure and Conversion Factors. 62 additional articles. Index.

Plant Viruses, Subviral RNAs and Viroids.- Contribution of Plant and Virus Genes to Cauliflower Mosaic Virus Pathogenicity.- Bromovirus RNA Replication and Host Specificity.- Analysis of Tobacco Mosaic Virus-Host Interactions by Directed Genome Modification.- Cell-to-Cell Movement of Plant Viruses.- Tomato Spotted Wilt Virus: A Bunyavirus Invading the Plant Kingdom.- Origin and Evolution of Defective Interfering RNAs of Tomato Bushy Stunt Virus.- Self-Cleavage Activities from Viral Satellite RNAs.- Viroid Structures Involved in Protein Binding and Replication.- Analysis of Viroid Pathogenicity by Genome Modification.- Nitrogen Fixation, Nitrogen Metabolism.- An Extracellular Oligosaccharide Symbiotic Signal Produced by Rhizobium meliloti.- Tissue-Specific Expression of Eariy Nodulin Genes.- Internalization of Rhizobium by Piant Cells: Targeting and Role of Peribacteroid Membrane Nodulins.- Regulation of Nodule Specific Genes.- Regulation of Genes for Enzymes along a Common Nitrogen Metabolic Pathway.- Phytopathology.- Molecular Basis of Plant Defense Responses to Fungal Infections.- Plant Genes Involved in Resistance to Viruses.- Repeated DNA Sequences and the Analysis of Host Specifity in the Rice Blast Fungus.- Molecular Genetics of the Tomato Pathogen Cladosporium fulvum.- Transgenic Potato Cultivars Resistant to Potato Virus X.- Agrobacterium, Transformation.- The Agrobacterium Virulence System.- T-DNA Gene-Functions.- Morphogenetic Genes in the T-DNA of Ri Plasmids.- Transient Expression and Stable Transformation of Maize Using Microprojectiles.- Agroinfection as a Tool for the Investigation of Plant-Pathogen Interactions.- Physical Mapping of the Arabidopsis Genome and its Applications.- Application of Restriction Fragment Length Polymorphism to Maize Breeding.- Soybean Genome Analysis: DNA Polymorphisms are Identified by Oligonucleotide Primers of Arbitrary Sequence.- Genome Analysis in Brassica Using RFLPs.- Physical Mapping of DNA Sequences on Plant Chromosomes by Light Microscopy and High Resolution Scanning Electron Microscopy.- Transposons.- Structure and Function of the Maize Transposable Element Activator (AC).- Expression and Regulation of the Maize Spm Transposable Element.- The En/Spm Transposable Element of Zea mays.- The Mechanism and Control of Tam3 Transposition.- Characterization of Mobile Endogenous Copia-Like Transposable Elements in the Genome of Solanaceae.- Mitochondria, Chloroplasts, Photosynthesis.- Organization and Evolution of the Maize Mitochondrial Genome.- RNA Editing in Wheat Mitochondria: A New Mechanism for the Modulation of Gene Expression.- Topological Orientation of the Membrane Protein URF13.- Cytoplasmic Male Sterility in Petunia.- Nuclear and Chloroplast Genes Involved in the Expression of Specific Chloroplast Genes of Chlamydomonas reinhardtii.- The Thylakoid Membrane of Higher Plants: Genes, their Expression and Interaction.- Greening of Etiolated Monocots - The Impact of Leaf Development on Plastid Gene Expression.- Regulation of Chloroplast Biogenesis in Barley.- Chlorophyll Biosynthesis.- Molecular Approaches to Understand Sink-Source Relations in Higher Plants.- Gene Expression, Photoreceptors.- The Expression of an Ovalbumin and a Seed Protein Gene in the Leaves of Transgenic Plants.- Regulation of Plant Gene Expression by Antisense RNA.- Photocontrol of Gene Expression.- phyA Gene Promoter Analysis.- Approaches to Understanding Phytochrome Regulation of Transcription in Lemna gibba and Arabidopsis thaliana.- Cis-Regulatory Elements for the Circadian Clock Regulated Transcription of the Wheat cab-1 Gene.- Plant Development.- Self-Incompatibility as a Model for Cell-Cell Recognition in Flowering Plants.- Floral Homoeotic and Pigment Mutations Produced by Transposon-Mutagenesis in Antirrhinum majus.- Molecular Analysis of the Homeotic Flower Gene deficiens of Antirrhinum majus.- Mutations of Knotted Alter Cell Interactions in the Developing Maize Leaf.- T-DNA Insertion Mutagen...

Oviductal Recognition of Embryonic Signals; H.B. Croxatto, et al. Effect of Progesterone Antagonists on Ovo-Endometrial Interactions; A. Psychoyos. On the Requirement for Estrogen for Establishing Pregnancy in the Non-Human Primate; N.R. Moudgal. Embryonic Loss and Conceptus Interferon Production; R.M. Roberts. In Vitro Models of Implantation; S.R. Glasser, et al. Uterine EGF Ligand-Receptor Circuitry and Its Role in EmbryoUterine Interactions during Implantation in the Mouse; S.K. Dey, et al. Human Uterine Angiogenic Factor (HUAF). The Role of Lymphohematopoietic Cytokines in Signalling between the Immune and Reproductive Systems; T.G. Wegmann. Human Decidual Function in Trophoblast and Uterine interaction; T. Mori, et al. Cytokines at the Maternal Fetal Interface: Colony Stimulating Factor1 as a Paradigm for the Maternal Regulation of Muridae Rodents; C. Tachi. Hormonal Regulation of Uterine Complement; K.B. Isaacson, et al. Insulinlike Growth Factor Binding Proteins: A Paradigm for Conceptus-Maternal Interactions in the Primate; A.T. Fazleabas, et al. The Roles of Growth Factors and Their Receptors in Peri-Implantation Mouse Embryos and at the Embryomaternal Interface; Z. Werb, et al. Ligands and Receptors of the Insulin Family: Role in Early Mammalian Development; S. Heyner, et al. 6 additional articles. Index.

I. Clinical Topics.- The Clinical Profile of Sepsis and the Adult Respiratory Distress Syndrome.- The Participation of the Complement System in Atherosclerotic Vascular Disease.- The Spectrum of Atherosclerosis in the Human.- Cerebral Endothelial Injury in Stroke, Brain Trauma and Hypertension.- II. General Concepts in Endothelial Cell Pathophysiology.- Free-Radical Mediated Actions on Endothelial Cells of the Intact Lung.- Regulation of Vascular Function by Vascular Permeability Factor.- III. Chemical Mediators of Endothelial Cell Injury.- Endothelial Cells as Targets for and Producers of Cytokines.- Roles of Vascular Cells in Inflammation and Immunopathology.- The Biochemistry, Cell and Molecular Biology of Type 1 Plasminogen Activator Inhibitor.- IV. Endothelial Cell Interaction with Blood Components.- Purine Regulation of Endothelial Cells: Relevance to Pathophysiology.- Autoantibodies to Endothelial Cells.- Leukocyte-Endothelial Cell Interactions.- V. Vascular Responses to Endothelial Cell Injury.- Endothelial Function in Human Coronary Bypass Grafts.- Altered Renovascular Endothelial Functions During Nephrotoxicity.- Cerebral Endothelial Function: Physiology and Pathophysiology.- Mechanisms of Altered Reactivity in the Cerebral Microcirculation.- VI. Mechanisms of Endothelial Cell Dysfunction.- The Role of Apolipoprotein E and Apolipoprotein B in Atherosclerosis.- Endothelial Cell-Matrix Interactions in Health and Disease.- Biosynthesis and Assembly of von Willebrand Factor by Vascular Endothelial Cells: Relevance to Pathophysiology.- VII. Markers of Endothelial Cell Injury and Repair.- Monitoring of Endothelial Plasmalemmal Ectoenzyme Function as an Index of Endothelial Injury and Repair.- Pathophysiological Significance of Endothelial Cell Integrins.- VIII. Epilogue.- Vascular Endothelium: Physiological Basis of Clinical Problems.- IX. Abstracts of Oral and Poster Presentations.- X. List of Participants.- XI. Index.

Shear Flows: Experimental Observations: The Mixing Transition in Free Shear Flows; A. Roshko. Vortex Shedding from Spheres at Subcritical Reynolds Number in Homogeneous and Stratified Fluid; P. Bonneton, et al. Nature of the Görtler Instability: A Forced Experiment; J.M. Chomaz, et al. Control Experiments: Control of Turbulent Shear Flows via Stationary Boundary Conditions; H.E. Fielder, et al. The Effects of External Excitation on the Reynolds-Averaged Quantities in a Turbulent Wall Jet; E. Horev, et al. Control of Organized Structures in Round Jets at High Reynolds Numbers; P.J.D. Juvet, et al. Numerical Experiments: Advances and Some Novel Experiments using Direct Numerical Simulations of Turbulence; P. Moin. Bubble Formation in Dense Fluidized Beds; J.A. Hernández, et al. Three Dimensional Numerical Simulations of Coherent Structures in Free Shear Flows; M. Lesieur, et al. Closed Flows: Experiments: Effect of Noise on Bifurcations and Patterns in Dissipative Systems; G. Ahlers. Hexagonal Convective Cells; C. Pérez-García, et al. Theoretical Models: The NS and Related Equations: Vortex Dynamics and Turbulence; P.G. Saffman. Control of Boundary Layer and Dynamical Systems Theory: An Update; G. Berkooz, et al. 19 additional articles. Appendices. Index.

Rudolph Altschul: Man and Scientist.- 1 The Dynamic Vessel Wall.- Natural History of Atherosclerosis.- Adaptations of Mature and Developing Arteries to Local Hemodynamics.- The Cytoskeleton of Arterial Smooth Muscle Cells during Development, Atheromatosis and Tissue Culture.- 2 Vascular Wall Injury and Repair.- Repair of Arterial Endothelium.- The Role of the Cytoskeleton in Endothelial Repair.- Thrombin-Stimulated Endothelial Cell Functions: Monocyte Adhesion and PDGF Production.- 3 Extracellular Matrix Interactions in Atherogenesis.- Dynamic Responses of Collagen and Elastin to Vessel Wall Perturbation.- Dynamic Interaction of Proteoglycans.- Endothelial Cell - Extracellular Matrix Interactions: Modulation of Vascular Cell Phenotype by Matrix Components and Soluble Factors.- 4 Autocrine and Paracrine Control of Vascular Tissue.- Regulation of PDGF Expression in Vascular Cells.- Endothelial Regulation of Vasomotor Tone in Atherosclerosis.- Production of Cytokines by Vascular Wall Cells: An Update and Implications for Atherogenesis.- 5 Thrombosis and Fibrinolysis.- Hypoxia and Endothelial Cell Function: Alterations in Barrier and Coagulant Properties.- Regulation of Type One Plasminogen Activator Inhibitor Gene Expression in Cultured Endothelial Cells and the Vessel Wall.- Platelet Reactions in Thrombosis.- Eicosanoid Metabolism and Endothelial Cell Adhesion Molecule Expression: Effects on Platelet/Vessel Wall Interactions.- 6 Lipids in Atherogenesis.- Receptor-Mediated Low Density Lipoprotein Metabolism.- The Molecular Basis for Lipoprotein Interaction with Vascular Tissue.- Cholesterol: Is there a Consensus?.- Contributors.

1: Fundamentals.- 1.1 Introduction.- 1.2 Data Aquisition.- Map Construction.- Interpolation.- 1.3 Spatial Sampling.- 1.4 Reference and Reference-Dependence.- 1.5 Map Display Methods.- Scaling and Floating Voltage Scales.- Summary Maps.- 1.6 Identification of Topographic Features.- 1.7 Spike Mapping.- 1.8 Post-Processing.- Analog Front-end.- Digital Filtering.- Reference Manipulation.- Statistical Mapping.- Global Field Power.- Correlation Analysis.- Source Localization.- 1.9 Frequency Analysis.- 2: Source Modelling and Analysis.- 2.1 Concepts of a Source.- 2.2 Physical Model.- 2.3 Inverse Solution.- 2.4 Stability of Dipole Solutions.- 2.5 Data Characterization.- 3: Magnetoencephalography.- 3.1 Instrumentation.- 3.2 Meg Measurements and Generators.- Meg Generators.- Regional Generators.- The Inverse Problem for MEG.- 3.3 Spontaneous MEG Rhythms.- 3.4 Review of MEG Studies.- 3.5 Concerns and Outlook.- 4: Statistical Approaches.- 4.1 Introduction.- 4.2 Assumptions and Difficulties.- 4.3 Normative Data.- 4.4 Statistical Comparisons.- 4.5 Classification.- 4.6 Exploratory vs. Confirmatory Analysis.- 5: Selected Normative Data.- Flash VEP.- Pattern Reversal VEP.- P300 AEP.- Resting EEG.- References.

I LECTURES - Banff NATO ASI Physics, Geometry & Topology.- Field Theory Methods and Strongly Correlated Electrons.- Braid Statistics in Three-Dimensional Local Quantum Theory.- On the Algebraic Structure of the BRST Symmetry.- Black Hole Quantization and a Connection to String Theory.- An Introduction to General Topology and Quantum Topology.- Topics in Planar Physics.- to Conformal Field Theory and Infinite Dimensional Algebras.- Lectures on RCFT.- Chern-Simons Gauge Theory and the Spin-Statistics Connection in Two Dimensional Quantum Mechanics.- Yang-Baxter Algebras, Integrable Theories and Quantum Groups.- Symmetry and Functional Integration.- Topological Aspects of the Quantum Hall Effect.- II SEMINARS - Workshop on Physics, Braids & Links.- The Nonabelian Chern-Simons Term with Sources and Braid Source Statistics.- The Quantum Group Method of Quantising the Special Linear Group SL(2, C).- 2+1 Dimensional Quantum Gravity and the Braid Group.- Finite Renormalization of Chern-Simons Gauge Theory.- A New Family of N-State Representations of the Braid Group.- Link Polynomials and Solvable Models.- Integrable Restrictions of Quantum Soliton Theory and Minimal Conformal Series.- Tangles, Links and Twisted Quantum Groups.- Participants (Group photo, pg 656)

Lectures.- Some Stochastic Techniques in Quantization, New Developments in Markov Fields and Quantum Fields.- Random Surfaces: A Non-perturbative Regularization of Strings?.- From Lattice Gauge Theory Towards Gravity.- Geometric Continuum Regularization of Quantum Field Theory.- Quantization = Geometry + Probability.- Simulation of Staggered Fermions by Polymer Algorithms.- All Gauge Orbits and Some Gribov Copies Encompassed by the Gribov Horizon.- Lattice Gauge Theories.- Beyond the Gribov Horizon in the Femto Universe.- The O (N)-symmetric Non-linear ?-model to Three Leading Orders in 1/N.- Simulations of Lattice QCD with Dynamical Fermions.- Stochastic Overrelaxation Algorithms and Critical Slowing down.- Slave Equations for Connected Correlation Functions.- The Monomer-Dimer Algorithm and QCD at Finite Density.- The Theory of Hybrid Stochastic Algorithms.- Numerical Investigation of Four-Dimensional Field Theories.- Quantum Gravity.- Probabilit?, Time and Gravity.- Simplicial Quantum Gravity from Two to Four Dimensions.- BRS Symmetry in Stochastic Quantization of the Gravitational Field.- Solved and Unsolved Problems in the Stochastic Quantization of Gravity.- Brs Symmetry and Supersymmetry in Stochastic Quantization.- Hidden BRST Symmetry and Large N.- On Gauge Invariances in Stochastic Quantization.- Critical Dynamics, Stochastic Quantization and Supersymmetry.- Renormalization in Stochastic Quantization and Supersymmetry.- Random Walks and Random Surfaces.- Random Walk Representation of Propagators for Particles with Spin.- The Critical Behavior of a Nontrivial Random Surface Model.- Random Surfaces with Ising Spins.- The Use of Fourier Acceleration in the Langevin Simulation of Random Surfaces.- Miscellany.- Path Integral Approach to Classical Mechanics.- An Approach to Quantum Field Theory Through Stochastic Equations.- Remarks on the Renormalisation of Fermions Coupled to Gauge Fields in the Zwanziger Gauge.- The Parisi-Wu Method and Quantum Chaos.- Participants.

Quantum Communication and Information Theory: Information Theoretic Interpretations of von Neumann Entropy; R. Jozsa. Quantum Information Theory, the Entropy Bound, and Mathematical Rigor in Physics; H.P. Yuen. Classical and Quantum Information Transmission and Interactions; C.H. Bennett. Bounds of the Accessible Information under the Influence of Thermal Noise; M. Ban, et al. Quantum Computing: Quantum Computing and Decoherence in Quantum Optical Systems; J.I. Cirac, et al. Unitary Dynamics for Quantum Codewords; A. Peres. Quantum Error Correction with Imperfect Gates; A.Y. Kitaev. Eliminating the Effects of Spontaneous Emission in Quantum Computations with Cold Trapped Ions; C. D'Helon, G.J. Milburn. Quantum Measurement Theory and Statistical Physics: On Covariant Instruments in Quantum Measurement Theory; A.S. Holevo. Quantum State Reduction and the Quantum Bayes Principle; M. Ozawa. On the Quantum Theory of Direct Detection; A. Barchielli. Homodyning as Universal Detection; G.M. D'Ariano. Quantum Optics: Atom Lasers; C.M. Savage, et al. Measurement of Quantum Phase Distribution by Projection Synthesis; D.t. Pegg, S.M. Barnett. Quantum Optical Phase; S.M. Barnett, D.T. Pegg. 42 Additional Articles. Index.