Bøger i Nato ASI Series serien

Photophysics: The Nature of the Light Field in Biological Media B.C. Wilson. Photochemistry: Quantum Yield of a Photochemical Reaction; R.H. Potter, et al. Photosensitization: Photosensitization: Reaction Pathways; J.E. van Lier. Photosynthesis: Near Infra-Red Flash Absorption: A Tool for Studying Photosynthesis; P. Mathis, et al. UV Effects: Response to Ultraviolet Radiation in a Simple Eukaryote; (Yeast): Genetic Control and Biological Consequences; D. Averbeck, et al. Environmental Photobiology: Isolation and Biological Consequences of Plant Derived Phototoxins; J.T. Arnason, et al. Vision: Visual Pigments: Absorbance Spectra and Photoproducts; J.K. Bowmaker. Photomorphogenesis: Photomorphogenesis Responses to UV Light: Involvement of Phytochrome and Photoreceptors; B. Lercari. Photomovement: Photomovement; W. Nultsch, et al. Bioluminescence: Bioluminescence: Biochemistry for Fun and Profit; J. Lee. Photomedicine: Photomedicine: Photodermatology B. Johnson. Other Experiments: Experiments Reprinted from The Science of Photobiology, First Edition; K.C. Smith. Appendix: Units of Measure and Conversion Factors. 62 additional articles. Index.

Introduction: Atomic Physics and Nuclear Properties; J. Bauche. Atomic Methods in Nuclear Spectroscopy: Progress in Atomic Physics Experiments on Nuclear Properties; R. Neugart. Single Particle Aspects: Single Particle Response Function; S. Gales. Multiphonon States: Low-Energy Multiphonon States in Deformed Nuclei; R. Piepenbring. Shapes and Coexistence: Algebraic Approaches to Nuclear Structure; R.F. Casten. Octupoles: Reflection-Asymmetric Shapes in Atomic Nuclei; W. Nazarewicz. Superdeformation: Microscopic Description of Superdeformation at Low Spin; R. Bonche, et al. Exotic Nuclei: Search for New Radioactivities at the Proton-Drip Line; F. Pougheon, et al. Chaos: Quantum Chaos and Low-Energy Nuclear Spectroscopy; M.J. Giannoni. Experimental Techniques: Nuclear Moments by Orientation Methods; H. Postma. 35 additional articles. Index.

Studies of Reovirus Pathogenesis Reveal Potential Sites for Antiviral Intervention.- Drugs as Molecular Tools.- Genetically Engineered Bacteria to Identify and Produce Antiviral Agents.- Antiviral Agents from Novel Marine and Terrestrial Sources.- Virus Receptors: The Achilles' Heel of Human Rhinoviruses.- Therapeutic Strategies Employing CD4, The HIV Receptor.- Molecular Characterization of HIV-2 (ROD) Protease following PCR Cloning from Virus Infected H9 Cells.- A Novel, Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase (Review).- Catalytic Antisense RNA (Ribozymes): Their Potential and Use as Anti-HIV-1 Therapeutic Agents.- Therapies for Hepatitis B Virus: Current Status and Future Possiblities.- A Preliminary Report of a Controlled Study of Thymosin Alpha-1 in the Woodchuck Model of Hepadnavirus Infection.- Delta Virus as a Vector for the Delivery of Biologically Active RNAs: Possibly a Ribozyme Specific for Chronic Hepatitis B Virus Infection.- Inhibition of Herpes Simplex Virus Ribonucleotide Reductase by Synthetic Nonapeptides: A Potential Antiviral Therapy.- Antiviral Effects of Herpes Simplex Virus Specific Anti-Sense Nucleic Acids.- Heterogeneity of a Herpes Simplex Virus Clinical Isolate Exhibiting Resistance to Acyclovir and Foscarnet.- Cellular Metabolism and Enzymatic Phosphorylation of 9-(2-Phosphonylmethoxyethyl) Guanine (PMEG), a Potential Antiviral Agent.- Effect of Herpes Simplex Virus Type 1 Infection on Cytokine Gene Expression in Activated Murine Peritoneal Macrophages.- Procedure for Evaluation of Neutralizing Antibody to Cytomegalovirus in Commercial Intravenous Gamma Globulin Preparations.- Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation ELISA.- Emerging Trends in the Rapid Detection of Viruses.- DNA Probes for Viral Diagnosis.- Contributors.

Histopathology of Bronchial Asthma; P.K. Jeffery. Airway Neuropeptides; P. Barnes. Potential Role of Mast Cell Proteases in Asthma; J. Nadel. Human Mast Cells, Basophils, and their Mediators; V. Casolaro, et al. Platelets and Asthma; J. Morley, et al. Leukotrienes and Asthma; J. Rokach, et al. Plasma Exudation in Asthma and its Pharmacological Control; C. Persson. Synthesis and Regulation of IgE in Asthma; G. Del Prete. Osmotic and Ionic Factors in Bronchial Responsiveness; S. Bianco, et al. Airway Responsiveness, Late-Phase Response, and Inflammation in Allergic Asthma; V. Brusasco, et al. Injury and Repair of the Airway Epithelium in Asthma; S. Rennard, et al. Bronchial Asthma and Pulmonary Gas Exchange; R.R. Rodriguez. Asthma Management; A. Tattersfield. The National Asthma Education Program; S. Hurd. Management of Asthmatic Children; K.F. Kerrebijn. 12 additional articles. Index.

Compartmentation in Aromatic Metabolism; F. Hrazdina. Immunolocalization of Flavonoid Conjugates and their Enzymes; R.K. Ibrahim. General Phenylpropanoid Metalbolism; C.J. Douglas, et al. Molecular Biology of Stress-Induced Phenylpropanoid and Isoflavonoid Biosynthesis in Alfalfa; R.A. Dixon, et al. Biosynthesis and Metabolism of Isoflavones and Pterocarpan Phytoalexins in Chickpea, Soybean, and Phytopathogenic Fungi; W. Barz, R. Welle. Flavonoid Synthesis in Petunia Hybrida; A.G.M. Gerats, C. Martin. Flavonoids; D.A. Phillips. Flavonoid Sulfation; L. Varin. Synthesis and Base-Catalyzed Transformations of Proanthocyanidins; D. Ferreira, et al. Enzymatic Synthesis of Gallotanins and Related Compounds G.G. Gross. Enantioselective Separations in Phytochemsitry; L.B. Davin, et al. The Phytochemical Society of North America; S.A. Brown. Index.

Outstanding Problems in Cancer Risk Assessments: Pharmacodynamic Models for Cancer Risk Assessment; S.H. Moolgavkar. Oncogenes: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogene Assessment and Human Cancer; D.A. Spandidos, M.L.M. Anderson. Transgenics: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogenic Transgenic Mice in the Study of Carcinogenesis; C.H. Ahn, W.C. Choi. Case Studies: Review of Methylene Chloride Cancer Risk Assessment: Cancer Dose-Response Modeling and Methylene Chloride; G. Charnley. Case Studies: Review of Benzene Cancer Risk Assessment: Risk Assessments for Benzene-Induced Leukemia; K.S. Crump. Concluding Remarks: Findings and Recommendations; C. Zervos. Index.

tRNA and AminoacyltRNA Synthetases: Charging of RNA Microhelices and Decoding Genetic Information; P. Schimmel. rRNA and mRNA: Regulation, Processing, and Assembly: Genetic Approaches to the Study of Eukaryotic Ribosomes; J.R. Warner, et al. Translational Initiation and Termination: Mechanisms of Translational Initiation and Repression in Prokaryotes; D.E. Draper. The Elongation Process: Sites, Factors, Nascent Chain: The Allosteric ThreeSite Model and the Mechanism of Action of Both Elongation Factors EFTu and EFG; K.H. Nierhaus, et al. Accuracy in Translation: Mutants of tRNA, Ribosomes, and mRNA Affecting Frameshifting, Hopping, or Stop Codon Read-Through; J.F. Atkins, et al. Quaternary Structure, Functional Centers, and Domains in the Ribosome. Translation in Cell Organelles. The Translational Apparatus and Evolution. 64 additional articles. Index.

Polyatomic Ion Dissociative Recombination; D.R. Bates. Recent Developments and Perspectives in the Treatment of Dissociative Recombination and Related Processes; A. Guisti-Suzor, et al. Electron-Ion Continuum-Continuum Mixing in Dissociative Recombination; S.L. Guberman. Recent Merged Beam Investigations of Hydrogen Molecular Ion Recombination; J.B.A. Mitchell, et al. Recent Flowing Afterglow Measurements; B.R. Rowe. Recombination of Cluster Ions; R. Johnsen. Associative Ionization of Hydrogen; F. Brouillard, X. Urbain. Resonant Theory of Dissociative Attachment; I.I. Fabrikant. Dissociative Recombination in Planetary Ionospheres; J.L. Fox. Chemistry of Supernova 1987a; A. Dalgarno. Factoring Sequences of Dynamic Processes in a Single Collision; F.H. Mies. Dissociative Electron Attachment to TransitionMetal Hydrides; T.M. Miller, et al. Electron Impact Dissociative Excitation of Molecular Ions; A.E. Orel. 17 additional articles. Index.

Nuclear Collisions and Structure: Descriptions of Heavy Ion Collisions at Intermediate Energies; E. Lehman. Boltzman Master Equation Theory of Nuclear Reactions; M. Cavinato, et al. Formation and Decay of Hot Nuclei; B. Tamain. Statistical and Dynamical Aspects of Hot Nucleus DeExcitation; M. Gui et, al. Atomic Collisions: New Means and Objectives in the X and XUv Spectroscopy and Imagery; Y. Cauchois. Collisions of Molecules with Clusters; J. Jellinek, Z.B. Guvenc. Theory of Slow Atomic Collisions; F. Masnou-Seeuws. RMatrix Calculation of Multichannel Quantum Defect Parameters in Heavy Alkaline Earth Atoms; M. Aymar. New Phenomena at High Energy Collisions: Renaissance of Interest in Cosmic Rays; H. Rebel. The Sharp Lepton Problem and the C(Q0) Scenario; J.J. Griffin. Electromagnetic and Mesonic Cherenkov Effects in Nuclear Media; W. Stocker, D.B. Ion. 16 additional articles. Index.

Progress in Genetic Engineering of the Pyridine and Propane Alkaloid Biosynthetic Pathways of Solanaceous Plants; R.J. Robins, et al. Molecular Genetic Techniques Applied the Analysis of Enzymes of Alkaloid Biosynthesis; T.M. Kutchan. Polyketide Biosynthesis; W.R. Strohl, R. Plater. The Biologists Palatte; N. Courtney-Gutterson. Engineering Altered Glucosinolate Biosynthesis by Two Alternative Strategies; R.K. Ibrahim, et al. Genetic Manipulation of Lignin and Phenylpropanoid Compounds Involved in Interactions with Microorganisms; R.A. Dixon, et al. The Genetic Origins of Biosynthesis and Light-Responsive Control of the Chemical UV Screen of Land Plants; R. Jorgensen. Genetic Control of Monterpene Biosynthesis in Mints; R. Corteau, J. Gershenzon. Genetic Manipulation of Terpenoid Phytoalexins in Gossypium; A.A. Bell. Analysis of Secondary Metabolism in Arabidopsis; C. Chapple. Polyphenol Oxidase; J.C. Steffens, et al. Genetic Regulation of Lignin Biosynthesis and the Potential Modification of Wood by Genetic Engineering in Loblolly Pine; S. Ronald, et al. Index.

Present and Future of Nuclear Physics; Introductory Lecture. Cluster Decay, Fission and Fusion: Cluster Radioactivity; P.B. Price. Recent Advances in Cluster Radioactivities; D.N. Poenaru, W. Greiner. Heavy Elements: Multinucleon Transfer Reactions-An Alternative Path to Heavy Element Synthesis; M.T. Magda. Microscopic and Semi-microscopic Approach to the Properties of Transactinide Nuclei; L. Bitaud, et al. Nuclear Structure: On the Origin of Rotations and Vibrations in Atomic Nuclei; J.P. Draayer, et al. Particle-rotor Model Description of Deformed Nuclei; A. Covello, et al. Weak Interaction and Double Beta Decay: Nuclear Aspects of Double Beta Decay; S. Stoica. A New Look to the Nuclear Structure Calculations of the PNC Cases in A=1821 Nuclei; M. Horoi. Nuclear Astrophysics: Recent Topics from Nuclear Reactions in the Energies Ranging from keV to GeV; K. Kubo. Heavy Ion Collisions: Processes in Peripheral Ultrarelativistic Heavy Ion Collisions; M. Greiner, et al. Miscellaneous Topics: Gamma and Meson Production by Cherenkovlike Effects in Nuclear Media; W. Stocker, D.B. Ion. 58 additional articles. Index.

Introduction. Phase Transitions in the Early Universe and Defect Formation; T.W.B. Kibble. The Topological Classification of Defects; M. Kleman. Introduction to Growth Kinetics Problems; G.F. Mazenko. Dynamics of Cosmological Phase Transitions: What Can We Learn from Condensed Matter Physics? N. Goldenfeld. Topological Defects and Phase Ordering Dynamics; A.J. Bray. The Production of Strings and Monopoles at Phase Transitions; R.J Rivers, T.S. Evans. Geometry of Defect Scattering; N.S. Manton. Theory of Fluctuating Nonholonomic Fields and Applications: Statistical Mechanics of Vortices and Defects and New Physical Laws in Spaces with Curvature and Torsion; H. Kleinert. String Network Evolution; E.P.S. Shellard. Global Field Dynamics and Cosmological Structure Formation; R. Durrer. Electroweak Baryogenesis; N.G. Turok. Dynamics of Cosmic Strings and Other Brane Models; B. Carter. Cosmological Experiments in Superfluids and Superconductors; W. Zurek. Cosmological Experiments in Liquid 4He-Problems and Prospects; P.C. Hendry et al. Index.

Terminology in Biological Rhythms; M.A. Ali, et al. Introduction to the Analysis of Periodic Phenomena; P. Legendre, P. Dutilleul. Biological Rhythms; M.P. Gerkema. Behavior and Rhythms in Fishes; D.L.G. Noakes. Ultradian Rhythms in Fishes; R.C. Peters, R.J. Veeneklaas. Tidally-Synchronised Behavior in Marine Fishes; R.N. Gibson. Lunar and Semi-Lunar Rhythms in Fishes; J.F. Leatherland, et al. Circadian Basis for Neuroendocrine Regulation; A.H. Meier. Sleep, Inactivity, and Circadian Rhythms in Fish; S. Reebs. Feeding-Entrained Circadian Rhythms in Fishes; R.E. Spieler. Melatonin Rhythms in the Pineal Organ of Fishes and its Effects; A. Zachmann, et al. Regulation of the Rhythmic Melatonin Secretion by Fish Pineal Photoreceptor Cells; J. Falcón, et al. The Rainbow Trout Pineal Organ; W.A. Gern, et al. 6 additional articles. Index.

Theoretical Background.- Genetic Approaches to Common Diseases.- A Candidate Gene Approach to the Genetics of Normal Lipid Variation: DNA Association Studies and Genotype by Environment Interaction.- Molecular Genetics Approach to Polygenic Disease - Initial Results from Atherosclerosis Research.- Diabetes.- Facilitative Glucose Transporters: Regulation and Possible Role in NIDDM.- Molecular Genetic Approach to Polygenic Disease: Dependent Diabetes Mellitus (NIDDM).- Lipids.- HDL and Reverse Transport of Cholesterol: Insights from Mutants.- Apolipoprotein E Polymorphisms and the Genetic Heterogeneity of Familial Dysbetalipoproteinaemia.- Abnormalities of Apolipoprotein B Metabolism in the Lipid Clinic.- Genetic Variation at the ApoA-I, CIII, A-IV Gene Complex: A Critical Review of the Associations between the Pst1 and Sst1 RFLPs at this Locus with Lipid Disorders.- The Molecular Basis of the Chylomicronemia Syndrome.- Lipoprotein Lipase Gene Variants in Subjects with Hypertriglyceridaemia and Coronary Atherosclerosis.- Atherosclerosis.- Atherosclerosis: The Genetic Analysis of a Multi-Factorial Disease.- RFLP Markers of Familial Coronary Heart Disease.- DNA Polymorphisms as Disease Markers.- Participants.

1. Chromatographic Processes.- Modelling Equilibrium and Kinetics in Chromatographic Processes.- Theory of Linear and Nonlinear Chromatography.- Hydrodynamics of Chromatographic Columns.- Cyclic Fixed Bed Sorption Processes for Bioseparations - Design Aspects.- Separations by Continuous Annular Chromatography.- Gradient Elution Chromatography.- Rate Processes in Supercritical Fluid Desorption and Extraction.- 2. Membrane Processes.- Fundamentals of Membrane Separation Processes.- Pressure-Driven Membrane Processes.- Ellectrically-Driven Membrane Processes.- Novel Membranes - Formation and Process Applications.- Cell Harvesting Using Cross-Flow Microfiltration.- Recovery of Intracellular Products.- Pervaporation in Biotechnology.- 3. Affinity Processes.- Affinity Chromatography: Principles and Applications.- Theory of Affinity Chromatography.- Affinity Partitioning.- Prediction of Partition Coefficients for Peptides in Aqueous Two-Phase Systems.- Membrane Affinity Filtration.- 4. Design of Separation Media.- Affinity Chromatography: Design of Biospecific Chromatographic Materials.- Membranes for Bioprocessing: Design Considerations.- 5. Scale-Up, Optimization and Process Integration.- Operating Modes, Scale-up and Optimization of Chromatographic Processes.- Scale-up and Optimization of Membrane Processes.- Simultaneous Reaction and Chromatography.- Membrane bioreactors.- Recombinant Human Tissue-Plasminogen Activator: Biochemistry, Pharmacology, and Process Development.- List of Contributors and Participants.

Proceedings of the NATO Advanced Study Institute on Polymer Colloids, University of Bristol, U.K.