Bøger i Recent Results in Cancer Research serien

Morbidity and mortality from heart disease and stroke are probably due both to disease and to changes of aging. cancer is clearly a disease and is not a change expected with aging. In the United States about one-half of all cases of cancer are diagnosed after age 65, although those over 65 comprise less than one-eighth of the population.

Several papers dealing with the clinical relevance of steroid hormone receptors in breast cancer have already been published. We hope that this book will enable the reader to become acquainted with the present state of European steroid hormone receptor studies devoted to breast cancer treatment.

Sadly, the incidence of the disease continues to increase in women in the United Kingdom, and the success of commercial pressure to encourage cigarette smoking in the developing countries must mean that an increasing community health problem may be anticipated.

With contributions by numerous experts

Predictive drug testing on human tumor cells in order to define the appropriate chemotherapy will remain imperative as long as the anticancer agents available are few in number and show only limited activity.

Sponsored by the Swiss League against Cancer

Driven by growing frustration about stagnating cure rates in breast cancer [1,4] and stimulated by elegant demonstration of highly curative effects of adjuvant systemic therapy in animal models [6, 11] and in several childhood neoplasias [15], researchers introduced ACT to the primary treatment of breast cancer with great hope some 15 years ago.

Proceedings of an International Symposium, 17-18 March 1983, Zurich University Hospital

Nielsen Image Quality in Mammography: Physical and Technical Limitations . Muir Clinical Considerations in Selection of Dedicated Mammography Units . Sickles Computed Tomography Scanning, Transillumination, and Magnetic Resonance Imaging of the Breast . Haus Recent Trends in Screen-Film Mammography: Technical Factors and Radiation Dose .

The decisive step in this development was the intensive investigation of one local ization by Papanicolaou: The application of cytology for screening in the field of gynecologic oncology made it an acknowledged technique.

Introduction and Definitions 1 Chapter 2. Biological Basis: Tumour Associated Antigens, the Immune Machinery and Its Behaviour Concerning Cancer Cells 5 2. The Immune Machinery 19 2. Humoral Mediated Immunity and Cell Mediated Immunity 19 2. The Immune Machinery and Cancer Cells 33 2. In vivo Evidence for Tumour Immunity 33 2.

CNRS International Colloquium, Held in Paris on June 22-24, 1977

Although pancreatic cancer is one of the most serious forms of cancers, the lack of clinical symptoms often limits curative treatment options. This book gives insight into the current understanding of the management of pancreatic cancer and considers recent findings in cancer research.

Different cancer types can result from a multiplicity of genetic and environmental factors. In recent years a number of genes have been identified as strong determinants for particular forms of cancer (particularly colon and breast cancer).

The discussion of some diseases is only occasionally enlivened by the emergence of new worthwhile facts.

Although skin cancer is the most common form of cancer and presents a consis tent problem in recognition, in treatment, and in prevention, it usually does not receive as much attention as other more deadly forms of cancer.

The writing of this monograph was stimulated on the one hand by experience gained in the study of "cancer families", and on the other, by the frequent perplexed and bewildered comments made by numerous physicians who have expressed amaze ment that we could think that "cancer is hereditary".

Over the past 50 years many in vitro and in vivo drug response assay systems have been developed to determine the potential - tivity of chemotherapy agents.

Scientific and Ethical Discipline in Clinical Trials on Acute Leukemia G. Although scientific technology was readily accepted and applied, scientific methodology has been accepted much more slowly and is very rarely properly applied.

The Vancouver conference was sponsored by the Cancer Control Agency of British Columbia, and was financially supported by Health and Welfare Canada (6610-1429-50), the Northern Califor nia Cancer Program (NCCP), Miles Laboratories (Canada), Bristol Myers Laboratories (Canada), and Plough Canada Inc.

Minimal neoplasia may be defined as a small cancer that has progressed beyond its site of primary origin into the surrounding tissue, but that has not yet reached the stage of deeper invasion or metastasization.

Physicians and biologists here present their experimental work in the field of hyperthermia, paying particular regard to its relevance in clinical situations. The main topics discussed are the effects of such treatment on normal tissues, animal tumors, malignant cell lines and human tumors.

It was especially appropriate for the Department of Surgery in Heidelberg, in close coopera tion with the Comprehensive Cancer Center Heidelberg/ Mannheim, to prepare a review of our present knowledge of surgical oncology as it is in the tradition of attempting to combine different therapeutic approaches to cancer therapy.

The ultimate "consumer" of the data presented at conferences on the primary treatment of operable breast cancer is the patient, and when, as in this disease, the benefits of therapy are relatively mod est, the availability and interpretation of the data from trials be comes an issue of primary importance.