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Parodontitis ist eine durch Zahnbelag hervorgerufene chronische entzündliche Erkrankung, die in das Parodontalgewebe eindringt und durch mikrobielle Dysbiose und die Immunantwort des Wirts verursacht wird. Sie zeichnet sich durch den Verlust des Alveolarknochens aus und kann, wenn sie unbehandelt bleibt, zu Zahnverlust führen, was wiederum die Mundfunktion beeinträchtigt und sich negativ auf die gesamte Lebensqualität auswirken kann. Für eine wirksame Vorbeugung und Behandlung des Zahns ist es daher notwendig, dass der Arzt diese Krankheiten frühzeitig und genau diagnostiziert. Derzeit basieren die Diagnose und die Einstufung von Parodontalerkrankungen auf einer vollständigen klinischen und röntgenologischen Untersuchung des Zahnhalteapparats.Jüngste Studien konzentrierten sich auf das subgingivale Mikrobiom, Entzündungsmediatoren und die Host-Response-Modifier als potenzielle Biomarker in der Gingivakrevikularflüssigkeit (GCF) und im Speichel, die das Potenzial für nicht-invasive Chairside-Diagnosehilfen nahelegen, um den Arzt bei der Diagnose und sogar bei der Prognose einer bestimmten Parodontalerkrankung zu unterstützen. Daher zielt dieses Buch darauf ab, einen Überblick über die bisher verfügbaren Chairside-Diagnosehilfen für die Parodontologie, ihre Bedeutung und ihre kommerziell erhältlichen Optionen zu geben.
A periodontite é uma doença inflamatória crónica induzida pela placa dentária que invade os tecidos periodontais, causada por uma disbiose microbiana e pela resposta imunitária do hospedeiro. Distingue-se pela perda de osso alveolar e, se não for tratada, pode levar à perda de dentes, o que, por sua vez, dificulta a função oral e pode ter um impacto negativo na qualidade de vida global. Por conseguinte, para uma prevenção e tratamento eficazes do dente, é necessário que o clínico diagnostique estas doenças precocemente e com exatidão. Atualmente, o diagnóstico e a classificação das doenças periodontais baseiam-se num exame clínico e radiográfico oral completo do periodonto.Estudos recentes centraram-se no microbioma subgengival, nos mediadores inflamatórios e nos modificadores da resposta do hospedeiro como potenciais biomarcadores presentes no fluido crevicular gengival (GCF) e na saliva, sugerindo o potencial de auxiliares de diagnóstico não invasivos, para ajudar o médico no diagnóstico e até no prognóstico de uma determinada doença periodontal. Assim, este livro tem como objetivo rever os auxiliares de diagnóstico periodontal disponíveis até à data, o seu significado e as opções disponíveis comercialmente.
La parodontite est une maladie inflammatoire chronique induite par la plaque dentaire qui envahit les tissus parodontaux, causée par une dysbiose microbienne et la réponse immunitaire de l'hôte. Elle se caractérise par la perte de l'os alvéolaire et, si elle n'est pas traitée, peut conduire à la perte des dents, ce qui entrave la fonction buccale et peut avoir un impact négatif sur la qualité de vie en général. Par conséquent, pour une prévention et une gestion efficaces de la dent, il est nécessaire que le clinicien diagnostique ces maladies de manière précoce et précise. Actuellement, le diagnostic et le classement des maladies parodontales reposent sur un examen clinique et radiographique complet du parodonte.Des études récentes se sont concentrées sur le microbiome sous-gingival, les médiateurs inflammatoires et les modificateurs de la réponse de l'hôte en tant que biomarqueurs potentiels présents dans le fluide créviculaire gingival (GCF) et la salive, suggérant le potentiel d'aides au diagnostic non invasives au fauteuil afin d'aider le clinicien dans le diagnostic et même le pronostic d'une maladie parodontale particulière. Par conséquent, ce livre vise à passer en revue les aides au diagnostic parodontal au fauteuil disponibles à ce jour, leur signification et leurs options commerciales disponibles.
Parodontit - äto wyzwannoe zubnym naletom hronicheskoe wospalitel'noe zabolewanie tkanej parodonta, obuslowlennoe mikrobnym disbiozom i immunnym otwetom hozqina. Ono harakterizuetsq poterej al'weolqrnoj kosti i pri otsutstwii lecheniq mozhet priwesti k potere zubow, chto, w swoü ochered', zatrudnqet funkcionirowanie polosti rta i mozhet negatiwno powliqt' na obschee kachestwo zhizni. Poätomu dlq äffektiwnoj profilaktiki i lecheniq zuba klinicistu neobhodima rannqq i tochnaq diagnostika ätih zabolewanij. V nastoqschee wremq diagnostika i klassifikaciq zabolewanij parodonta osnowywaütsq na polnom klinicheskom i rentgenograficheskom obsledowanii parodonta.Nedawnie issledowaniq sfokusirowali wnimanie na poddesnewom mikrobiome, mediatorah wospaleniq i modifikatorah reakcii hozqina kak potencial'nyh biomarkerah, prisutstwuüschih w desnewoj schelewoj zhidkosti (GCF) i slüne, chto ukazywaet na potencial neinwaziwnyh diagnosticheskih sredstw, kotorye mogut pomoch' wrachu w diagnostike i dazhe prognoze konkretnogo zabolewaniq parodonta. Takim obrazom, cel'ü dannoj knigi qwlqetsq obzor dostupnyh na segodnqshnij den' diagnosticheskih parodontal'nyh sredstw, ih znachenie i kommercheski dostupnye warianty.
La parodontite è una malattia infiammatoria cronica indotta dalla placca dentale che invade i tessuti parodontali, causata dalla disbiosi microbica e dalla risposta immunitaria dell'ospite. Si distingue per la perdita dell'osso alveolare e, se non trattata, può portare alla perdita dei denti, che a sua volta ostacola la funzione orale e può avere un impatto negativo sulla qualità di vita complessiva. Pertanto, per un'efficace prevenzione e gestione del dente, è necessario che il medico diagnostichi queste malattie in modo precoce e accurato. Attualmente, la diagnosi e la classificazione delle malattie parodontali si basano su un esame clinico e radiografico completo del parodonto.Studi recenti si sono concentrati sul microbioma sottogengivale, sui mediatori dell'infiammazione e sui modificatori della risposta dell'ospite come potenziali biomarcatori presenti nel fluido crevicolare gengivale (GCF) e nella saliva, suggerendo il potenziale di ausili diagnostici non invasivi alla poltrona per assistere il medico nella diagnosi e persino nella prognosi di una particolare malattia parodontale. Pertanto, questo libro si propone di passare in rassegna gli ausili diagnostici parodontali alla poltrona disponibili ad oggi, il loro significato e le opzioni disponibili in commercio.
Periodontitis is a dental plaque induced chronic inflammatory disease invading periodontal tissues, caused by microbial dysbiosis and the host immune response. It is distinguished by the loss of alveolar bone and if remain untreated can lead to tooth loss, which in turns hinders the oral function and can negatively impact the overall quality of life. Therefore for the efficient prevention and management of the tooth it is necessary for the clinician to diagnose these diseases early and accurately. Currently, the diagnosis and grading of periodontal diseases are based on complete oral clinical and radiographic examination of the periodontium. Recent studies focused on the subgingival microbiome, inflammatory mediators and the host-response modifiers as the potential biomarkers present in gingival crevicular fluid (GCF) and saliva, suggesting the potential for non-invasive chair side diagnostic aids in order to assist the clinician in the diagnosis and even prognosis of a particular periodontal disease. Hence, this book aims to review to date available chairside diagnostic periodontal aids, their significance and their commercially available options.
From the sands of the Sahara to the waters of the Pacific, the author provides a vivid, firsthand account of her travels to remote parts of the world like Tunisia in North Africa and Papua New Guinea (PNG) in the South Pacific. From diving and snorkeling in the coral rich waters of PNG to horse riding and camping in the dunes of the Sahara desert in Tunisia, Aditi Gupta talks of her adventures in this book. From studying at Port Moresby International School in PNG to working in Tunisia, she shares her unique life experience with readers.About the Author Aditi Gupta is an avid traveler who enjoys spending quality time in the sun, on the sand, and in the sea. She has worked as a Manager at Grant Thornton and PwC while also being a volunteer at Embracing the World, an NGO focused on uplifting underserved communities worldwide. She has an MBA in Finance from Cornell University and Bachelors in Electrical Engineering from National University of Singapore.
The fungal organism is a eukaryotic, microscopic, heterotrophic, unicellular or multicellular with inflexible cell wall compiled with chitin, glucan, and/or cellulose with a plethora of organelles. Fungi are ubiquitously found in air, soil, plants, and water even as a part of lichens growing on a rock. Diseases caused by fungi which have clinical significance are characterized as primary infections or opportunistic infections. Medicinal plants are available in India and used traditionally as these are rich sources of one or other secondary metabolites. The multiple actions and therapeutic uses of these indigenous plant products or drugs are sufficiently prescribed in classical literature in many medicinal plant volumes and pharmacopeias.
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