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Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention.--Publisher's website.
The conventional ac-dc conversion utilizes full wave bridge rectifier, and a capacitor as output filter. The ripple at the output of the capacitor is removed by the voltage regulator (dc-dc converter). Lot of harmonic currents at the load are undesirable because they produce distortion such as electromagnetic field interference (EMI), noise, etc. For distortion less output, line voltage and line current must have same phase. If line voltage and line current are not in same phase, then extra circuits must be adding to the converter to make the circuit in same phase. Line voltage and line current in same phase is called unity power factor, and the technique is called unity power factor correction. For ideal sine wave generator, its higher order harmonic currents do not contribute any power to the load but increase the root mean square (rms) current in the distribution line. As a result, it produces extra losses, which is undesirable. If the boost converter has unity power factor, then maximum active power is transferred to its load. As a result, ideal utility power factor is achieved.
Swamit Swarit- Literally meaning Infinitely bounded by self, being Intune with the self and leading us to the absolute abode of pleasure-Ananda. That is swamit swarit. This book is an interaction of the author with his unborn child and self-talks that he shares with the expecting mother and his wife to keep her positive and involved with different topics. Written in both english and hindi, swamit swarit will be good experience to expecting parents. The author has discussed various aspects of life and put some eternal questions for the child to decide.
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