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A Times Best Book of 2021 From the very first dog to glowing fish and designer pigs the human history of remaking nature. Virus-free mosquitoes, resurrected dinosaurs, designer humans such is the power of the science of tomorrow. But this idea that we have only recently begun to manipulate the natural world is false. We've been meddling with nature since the last ice age. It's just that we're getting better at it a lot better. Drawing on decades of research, Beth Shapiro reveals the surprisingly long history of human intervention in evolution through hunting, domesticating, polluting, hybridizing, conserving and genetically modifying life on Earth. Looking ahead to the future, she casts aside the scaremongering myths on the dangers of interference, and outlines the true risks and incredible opportunities that new biotechnologies will offer us in the years ahead. Not only do they present us with the chance to improve our own lives, but they increase the likelihood that we will continue to live in a rich and biologically diverse world.
"Humans seem to be destroying nature with incessant fiddling. We can use viruses to insert genes for pesticide resistance into plants, or to make the flesh of goldfish glow. We can turn bacteria into factories for millions of molecules, from vitamin A and insulin to diesel fuel. And this year's Nobel Prize went to the inventors of tool called CRISPR, which lets us edit genomes almost as easily as we can edit the text in a computer document. The potential for harm can seem both enormous and inevitable. In Life as We Made It, evolutionary biologist Beth Shapiro argues that our fears of new technologies aren't just mistaken, but they miss the big picture about human history: we've been remaking nature for as long as we've been around. As Shapiro shows, the molecular tools of biotechnology are just the latest in a long line of innovations stretching back to the extra food and warm fires that first brought wolves into the human fold, turning them into devoted dogs. Perhaps more importantly, Shapiro offers a new understanding of the evolution of our species and those that surround us"--
An insider's view on bringing extinct species back to lifeCould extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "e;ancient DNA"e; research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used-today-to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research-as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter-Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years-into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.
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