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Oral lichen planus (OLP) is an inflammatory, chronic and recurrent dermatosis. It can affect glabrous skin, dander and mucous membranes. Its etiopathogenesis remains unknown to this day, but an autoimmune hypothesis has been suggested. Clinically, the common reticular form of LPO is easily recognized, but the existence of numerous erosive, bullous, atrophic, nigricans or verrucous clinical forms, sometimes concomitant, can make diagnosis difficult. Diagnosis is based on a number of associated clinical and histological features. Only symptomatic forms are treated. A variety of treatments are available, including local corticosteroid therapy as first-line treatment, followed by systemic corticosteroid therapy as second-line treatment, or a combination of the two. In the event of failure, retinoids, immunosuppressants and PUVA therapy are the rule. Malignant transformation of LPO remains a controversial issue, despite the numerous studies published worldwide.
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