Bøger af Claudia Tanja (University of Leipzig) Mierke

This is the fourth volume of the highly regarded 'Physics of Cancer (Second Edition)' series, written with the aim of making very important topics in the physics of cancer visible to the research community. This fourth volume deals with mechanobiology using biophysical methods. The first chapter deals with mechanosensing and mechanotransduction on vastly different length scales. The second chapter discusses biophysical techniques for mechanical phenotype characterization of cells and nuclei. The third provides an overview of the mechanical phenotype of the plasma membrane. The fourth chapter contains the latest insights into the mechanical assessment of cell spheroids, organoids and tumoroids. The basic approach of this text is to present the latest promising findings to the scientific community, addressing scientists at all career stages.Key FeaturesFourth volume of the author's 'Physics of Cancer (Second Edition)' books, a highly regarded seriesComprises chapters that have been designed as self-contained unitsWritten by a widely respected expert in the physics of cancer fieldCovers state-of-the-art techniques that were developed by the authorIncludes research findings that have been presented in numerous peer-reviewed journal articlesContains extensive references at the end of each chapter to enhance further study

Physics of Cancer focuses on the mechanical properties of cancer cells and their role in cancer disease and metastasis. It discusses the role of the mechanical properties of interacting cells and the connective tissue microenvironment and describes the role of an inflammation during cancer disease. This outstanding book is the first to describe cancer disease from a biophysical point of view without being incomplete in describing the biological site of cancer. Originating in part from the author's own courses on tumor biology and cellular biophysics, this book is suitable for both students and researchers in this dynamic interdisciplinary field, be they from a physical, biological or medical sciences background.

This revised second edition isimproved linguistically with multiple increases of the number of figures andthe inclusion of several novel chapters such as actin filaments during matrixinvasion, microtubuli during migration and matrix invasion, nucleardeformability during migration and matrix invasion, and the active role of thetumor stroma in regulating cell invasion.

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.