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Since it is hardly possible to influence the first major component and improve the guidance of several thousands axons, the authors concentrated on the second major component and tried to reduce the collateral axonal branching.
Revealing the morphological correlate of antigen presentation in rodents, this text describes the method of immunoquenching of fluorescence which combines retrograde labelling and subsequent immunophenotypical characterization of cells.
Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons.
Using a combined morpho-functional approach the author recently found that polyinnervation of the neuro-muscular juction (NMJ) is the critical factor for recovery of function after transection and suture of the facial nerve. First, electrical stimulation was applied to the transected facial nerve or to paralysed facial muscles.
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