Bøger af Emma Richardson

Bacteriophages or phages are the viruses that infect bacterial cells. They replicate within these bacteria. Bacteriophages can be categorized on the basis of their morphological characteristics, nucleic acid content, site where they are usually found, and the bacterial target. Phage therapy is a specialized application of bacteriophages used for treatments wherein bacterial infections are treated using bacteriophages. The genomes of bacteriophage are used to encode highly pathogenic bacterial toxins including cholera toxin in Vibrio cholerae and diphtheria toxin in Corynebacterium diphtheria. Despite its benefits, there are some risks associated with phage therapy. For instance, it may lead to development of antibiotic resistance and reduced activity due to immune system response. This book contains some path-breaking studies on bacteriophage biology. The various advancements in bacteriophage research have been glanced at and their applications as well as ramifications have been analyzed in detail. The book will serve as a valuable source of reference for the graduate and postgraduate students.

A bacteriophage is a virus that can infect and replicate only inside a bacteria. They can kill bacteria without any negative effect on human or animal cells. They are referred to as phages and are the most common biological entities found on Earth. Bacteriophages vary in size, morphology, and genomic organization. Many phage-based technologies and therapies have been developed, especially in antibacterial treatments. There are several potential advantages of bacteriophages over antibiotics in terms of treating bacterial infections. Some of the benefits of bacteriophages are specificity of action (i.e., they kill only the pathogen they recognize), a considerable spectrum of activity, higher tolerability, and ease of administration. The results of various in-vitro studies have shown that bacteriophages could also be effective in the treatment of cystic fibrosis (CF) disorder. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the study of bacteriophages. It traces the recent developments in bacteriophage biology, technology and therapy. With state-of-the-art inputs by acclaimed experts of this field, this book targets medical students and professionals.

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