Bøger af Jaime Allison

Fluorescence-guided surgery (FGS) is a type of surgery that is performed with the guidance of fluorescence imaging. It has emerged as a new approach to detect the primary tumor, tumor margins, and metastatic lymph nodes. A major cause of tumor recurrence is the presence of residual tumor cells after surgery. Therefore, it is necessary to have a negative tumor margin to ensure a successful cancer resection. Despite widespread use of preoperative imaging techniques such as computed tomography (CT) scan, magnetic resonance imaging (MRI) scan, and positron emission tomography (PET) scan, the surgical margin positive rate failed to reflect remarkable improvement. The plausible reason for this failure is the reliance of surgeons on the visual inspection and intraoperative histopathological analysis of the frozen tissue specimen. FGS is now emerging as an effective tool to guide the surgical oncologists by generating real time fluorescence images of the surgical region. It reduces the possibility of recurrence of cancer. This book strives to provide a fair idea about the fluorescence-guided surgery and to help develop a better understanding of the latest advances related to this medical procedure. It is a vital tool for all researching and studying fluorescence-guided surgery as it gives incredible insights into the emerging trends and concepts.

Surgery is an important treatment option for cancer patients. Fluorescence-guided surgery (FGS) of cancer is an intraoperative medical technique that produces real time fluorescence image of the surgical region which helps the surgeons in performing the surgical procedure. Till now, various types of cancers such as head and neck cancer, breast cancer, lung cancer, esophagus cancer, hepatocellular carcinoma, gastric cancer, and melanoma have been treated with the help of FGS. Conventional imaging techniques such as CT and MRI are expensive and difficult and cannot be used at the time of surgery. On the other hand, FGS provides real-time imaging during surgery and it is less costly and easier to use. It is significant to achieve a negative tumor margin for a successful cancer resection as the presence of residual tumor cells after surgery may cause tumor recurrence that leads to poor prognosis. This book is compiled in such a manner, that it will provide an in-depth knowledge about the theory and practice of fluorescence-guided surgery of cancer. It aims to present researches that have transformed this discipline and have aided in its advancement. This book will help the readers in keeping pace with the rapid changes in this field.