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Reverse Vaccinology: Concept, Methods, and Advancement presents the development strategy of new vaccines through genome sequencing bioinformatics analysis. This book promises to revolutionize vaccine development, especially for pathogens to which the classical applications of Pasteur’s principles have failed, and it is explained in detail in this book.This book is split into three sections: the first, Concept, brings the basis of reverse vaccinology, vaccine antigen discovery, and subunit vaccine; the second, Tools and Methods, describes immunoinformatic, proteomics for epitope-vaccine design, databases, network analysis, machine learning, and NGS-driven antigen screening technology; and the last one, Disease Case Study, discusses real-world examples in the development of new vaccines for diverse diseases.It is a valuable resource for bioinformaticians, researchers, students, and members of the biomedical and medical fields who want to learn more about a new and agile process for the development of new vaccines.
This book looks at the recent developments in the area of photocatalytic degradation of dyes using photocatalytic techniques, for example by means of various nanoparticles, heterogeneous, and hybrid systems. Dyes are one of the major groups of water pollutants and are widely used in a diverse range of industries. The toxic effects of organic dyes in wastewater can have a great environmental impact, therefore there is significant interest and need to remove these dyes effectively and efficiently during wastewater treatment.This volume covers a plethora of basics on the photochemistry of dyes and provides information on technological perspectives including reactor designs and process intensification. Since many industries release a significant amount of colored effluents, which are toxic and difficult to remove by conventional methods, the comprehensive studies herein will contribute to helping reduce the impact of colored effluents in wastewater on the environment.
Biosensors for Emerging and Re-Emerging Infectious Diseases provides a review of how cornerstone optical, electronic, nanomaterial and data processing technologies can address detection issues occurring in a pandemic event. This book gives insights into the fundamental physical, chemical and biological mechanisms needed for such a type of detection. The content covers potential biomarkers which can be used for the infectious disease diagnostic, helping readers find the appropriate approach for the diagnosis of infectious diseases. It presents a novel approach to transferring the sensing platform from lab to application in clinics and to point of care detection. The book then moves on to discuss the function and efficiency of the biosensing platform in early diagnosis of infectious diseases compared to the standard methods. The required time, the technician skills and the steps which must be performed are other key factors of the biosensing platform which are well explained.
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