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A tuberculose (TB) é a única doença alguma vez declarada uma emergência mundial pela OMS e continua a causar grande mortalidade e sofrimento, especialmente nos países pobres e menos desenvolvidos. A sua associação com a pandemia de VIH/SIDA constitui uma combinação letal. O bacilo (Mycobacterium tuberculosis) tem uma parede celular muito espessa e complexa, o que faz com que este agente patogénico possa escapar às defesas imunitárias do hospedeiro e aos medicamentos anti-tuberculose. Neste livro, foi desenvolvido um método geral para a glicosilação C-C estereosselectiva e esta metodologia pode ser aplicada para sintetizar antigénios da tuberculose.
Tuberculosis (TB) is the only disease ever declared a global emergency by the WHO, it continues to cause great mortality and suffering, especially in poor and less-developed countries. Its association with the HIV/AIDS pandemic forms a lethal combination. The bacillu (Mycobacterium tuberculosis) has a very thick and complex cell wall which makes this pathogen could escape from the host¿s immune defense and the anti-tuberculosis drugs. In this book, a general method for stereoselective C-C glycosylaiton was developed and this methodology could be applied to synthesize Tuberculosis antigens.
Provides extensive and thoroughly exhaustive coverage of precision laser spectroscopy Presents chapters written by recognized experts in their individual fields Topics covered include cold atoms, cold molecules, methods and techniques for production of cold molecules, optical frequency standards based on trapped single ions, etc Applicable for researchers and graduate students of optical physics and precision laser spectroscopy
The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.
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