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Method Development in Analytical HPLC presents the essential information for understanding the process of developing an HPLC method of analysis. It includes foundational information related to HPLC, as well as discussion of sample types, the properties of analytes and matrices in the samples, and sample preparation, which is an important step in analytical methods development. The book provides analytical methods from literature, informs development of original methods with selection of the suitable type of HPLC, of specific columns, mobile phase, and detection techniques with emphasis on the use of mass spectrometry for detection, as well as optimization and validation methods. In addition, it includes useful details on method development for specific types of chromatography, such as RP-HPLC, HILIC, ion exchange, size exclusion, chiral, and information on green chemistry in analytical methods, computer assisted method development, and other key contemporary aspects of the subject.
Essentials in Modern HPLC Separations, Second Edition discusses the role of separation in high performance liquid chromatography (HPLC). This new and updated edition systematically presents basic concepts as well as new developments in HPLC. Starting with a description of basic concepts, it provides important guidance for the practical utilization of various HPLC procedures, such as the selection of the HPLC type, proper choice of the chromatographic column, selection of mobile phase and selection of the method of detection, all of which are in correlation with the physico-chemical characteristics of the compounds separated. Every chapter has been carefully reviewed, with several new sections added to bring the book completely up-to-date. Hence, it is a valuable reference for students and professors in chemistry. Provides a thoroughly updated resource, with an entirely new section on Computer-aided Method Development in HPLC and new subsections on miniaturization and automation in HPLC, chemometric aspects of HPLC, green solvent use in HPLC, and more Includes insights into the chromatographic process to find the optimum solution for analyzing complex samples Presents a basis for understanding the utilization of modern HPLC for applications, particularly for the analysis of pharmaceutical, biological, food, beverage and environmental samples
A follow-up to "Analytical Pyrolysis of Natural Organic Polymers", this book focuses on practical applications of analytical pyrolysis in synthetic organic polymer identification and characterization. It is suitable for both researchers and chemists working in analytical chemistry or in synthetic polymers.
Pyrolysis is involved in many practical applications as well as in many common human activities, but harmful compounds can be generated in the process. This title provides a comprehensive description of pyrolysis of non-polymeric organic molecules. It offers information on mechanisms and kinetics of numerous pyrolytic processes.
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