Bøger af Shruti Sharma

During their break, two childhood friends, Sean and John, met after four long college years. However, things turn dark when John realises that Sean is not the person he left, as he confesses to killing a man in their town. No one knows the reason, and with the ongoing investigation and limited time, can John find the missing piece and help his friend who was hiding something in disguise?

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This book is based on molecular profiling of Odontogenic tumors, which are distinct pathologic entity, require in depth understanding of their molecular and histogenetic origin to be applied in producing accurate diagnosis with meaningful prognostic indication. Molecular profiling should be considered to define a tumor and correlated in terms of origin, cell behaviour, diagnostic and prognostic outcome. Comprehensive evaluation of genetic, epigenetic, transcriptomic and metabolic profile of these tumors could help us to refine the understanding of these tumors and forms the epitome for further research. These lesions should now be seen from their molecular aspect rather than just their histogenetic, histopathologic or clinicopathological aspect alone. Molecules could help us delineate the boundaries between different tumour entities and further help in objectively refining the understanding of these lesions.

Controlling tooth movements in three dimensions has been made possible by the advent of fixed orthodontic appliances. However , increasing number of adults orthodontic patients have expressed the need for more esthetic , comfortable and hygienic alternate to fixed orthodontic appliances.In order to successfully delivery orthodontic treatment , clinicians need to carefully plan an appropriate therapeutic approach based on current scientific evidence,although this is not the only determining factorfor final decision as clinical experience & patient¿s opinion also play an important role , this information needs to be taken into consideration to assess the possibilities and limitation of each treatment modality.The possibility of using clear plastic appliances was introduced in 1945 by Dr, H.D. Kesling ,and in 1997 align technology introduced Clear Aligners Treatment as we know it. Clear Aligner Treatment is considered a comfortable and esthetic alternative , however , given the limited available evidence in certain earlier attempts and evaluation of effectiveness of clear aligners, strong conclusion regarding the investigated clinical efficiency of Clear Aligner Appliance were not fe

In the book, insights into the SARS-CoV-2 pathology, host¿s immune function including innate, cellular, and humoral responses, and immunomodulatory functions of SARS-CoV-2 including cytokine storm and immune evasion has been elaborated. The book sheds light on present clinical and laboratory-based applications enrolled in the SARS-CoV-2 diagnosis. Keeping sight on pathogenesis and SARS-CoV-2 immune function, current preventive and therapeutic strategies have been discussed. Further, the role of ACE receptors in the viral entry into the host cell, the effect of COVID-19 on the symptoms and prognosis of cardiovascular diseases (CVDs), impact of ACE inhibitors (ACEI), and angiotensin receptor blockers (ARBs) on CVD patients and also suffering from COVID-19 has been discussed. Nevertheless, the role of ACE2 genetic polymorphism during SARS-CoV-2 infection has been brought into light. Based on this information, modulation in ACE2 medications can be an alternative for the treatment of CVD patients infected with COVID-19 .