Bøger af Sudhanshu Kumar Bharti

The efficacy of medicinal plants in diabetic management is of great interest due to their beneficial effects on metabolic profile. In the present study, five herbal extracts and a prebiotic fructooligosaccharide produced from Aureobasidium pullulans have been evaluated alone as well as in formulation against T2DM. The formulation has been compared with L-carnitine having antioxidative, insulin mimetic, pancreatic ¿-cell restoration and enhancing glucose utilization properties, required for normal metabolism. Further, molecular docking was performed for documented active phytoconstituents from each extract for putative action mechanism concerning three proteins (PTP-1B, PPAR-¿ and DPP-IV) known to have diabetic therapeutic potential. Our in vivo, in vitro and in silico experiments revealed that the formulation has more effective antioxidant and antidiabetic property due to the presence of different types of active phytochemicals, which may have different mechanisms of action. This book is a step ahead, towards his contribution for combating T2DM through an elaborate and explicit account of a safe supplementary herbal formulation.

About one third of people worldwide are infected with a latent form of lung infection, with inactive bacteria Mycobacterium tuberculosis, that causes tuberculosis (TB). According to clinical research, conventional therapy combined with herbal therapy could offer a natural solution to TB. This book is a step ahead, dedicated to scientific world, a milestone to resolve the burning problems of tuberculosis & related disorder. The ginger plant (Gingiber officinale) can be of great therapeutic potential with reduced risk of side effects. This book shows how ginger plays a significant role in controlling molecular mechanism of inflammation by suppressing nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB), which is helpful in controlling TB and related disorder, as well as anemia. Although I have made every effort to make the book error free, I am under no illusion. I welcome comments, criticism and suggestion from the readers; it will help me make improvement in the next volume.