Bøger af Undurti N. Das

This book discusses the role of genes, oncogenes, anti-oncogenes, free radicals, PUFAs, anti-oxidants, lipid peroxidation process, telomere, and angiogenesis on the origin of cancer, cell proliferation, and cancer in general. It includes a broad introduction to cancer cells; genes, oncogenes, and anti-oncogenes; and free radicals. In later chapters, it discusses in depth the relationship among free radicals, lipid peroxidation and anti-oxidants in cell proliferation. It also discusses aerobic and anaerobic metabolism and their relationship to cancer, as well as the Warburg effect and its potential in the development of new targets for cancer management. Based on these and other evidences, Molecular Biochemical Aspects of Cancer introduces a novel concept that suggests that selective enhancement of free radical generation in tumor cells could form a strategy to induce apoptosis of cancer cells employing bioactive lipids. It presents a new method of treatment ofcancer using in vitro, in vivo and clinical data. This book will interest oncologists, scientists, molecular biologists, life scientists.

This book examines how the balance between pro- and anti-inflammatory molecules is related to health and disease. It suggests that this balance, or lack of it, initiates and aggravates many diseases and analyzes both them and new methods in their management.

Proposes that fetal growth retardation and low-grade systemic inflammation can be prevented by perinatal supplementation of long-chain polyunsaturated fatty acids (LCPUFAs). This book presents and discusses evidence for this hypothesis, along with possible mechanisms by which these substances produce beneficial actions.