Bøger af Vinod Kumar Tiwari

The medicinal potential of a polyherbal formulation is larger and longer than that of a single plant. As a consequence, Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens leaves were used to create Polyherbal Antidiabetic Sustained Release Matrix Tablets. The following plants were chosen after a thorough review of the literatureExhaustive literature was done on Plants having traditional use on anti-diabetic activity. Based on a literature review, four plants were chosen for polyherbal formulation: Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens. Plants had been collected and verified. Soxhlet extraction with hydroalcoholic solvent (Ethanol 70: Water 30) is used, to dried medicinal plants that have been collected. Phytochemical analysis of Alstonia scholaris, Centella asiatica, Corchorus trilocularis, and Morinda pubescens leaf extracts revealed the presence of many phytoconstituents. All extracts had peaks of marker phytoconstiuents on HPTLC, indicating their purity.The research had two goals: first to establish the anti-diabetic properties of the extract and secondly to develop and standardize formulation.

Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction and then followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology, and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells. In addition, diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry.