Bøger udgivet af Elsevier Science Publishing Co Inc

Machine Learning for Biomedical Applications: With Scikit-Learn and PyTorch presents machine learning techniques most commonly used in a biomedical setting. Avoiding a theoretical perspective, it provides a practical and interactive way of learning where concepts are presented in short descriptions followed by simple examples using biomedical data. Interactive Python notebooks are provided with each chapter to complement the text and aid understanding. Sections cover uses in biomedical applications, practical Python coding skills, mathematical tools that underpin the field, core machine learning methods, deep learning concepts with examples in Keras, and much more. This accessible and interactive introduction to machine learning and data analysis skills is suitable for undergraduates and postgraduates in biomedical engineering, computer science, the biomedical sciences and clinicians.

Biomedical Sensors and Smart Sensing: A Beginner''s Guide, a book in the 10-volume Primers in Biomedical Imaging Devices and Systems series, covers a wide range of interdisciplinary applications in imaging modalities, nuclear medicine, computed tomographic systems, x-ray systems, magnetic resonance imaging, ultrasound, and virtual reality. The series explores the essential fundamental techniques required to analyze and process signals and images for diagnosis, scientific discovery and medical applications. Volumes in this series cover a wide range of interdisciplinary areas, combining foundational content with practical case studies to demonstrate the applications of these technologies in real-world situations. In addition, the 10-volume series considers various medical devices, electronics, circuits, sensors and algorithms. Several applications ranging from basic biological science to clinical practice are included to facilitate ongoing research. Covers a variety of sensing and signal processing techniques Introduces different approaches relating to communication and intelligent data processing for early detection and prediction of diseases Includes practical case studies

600 pages

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Manganese Mining Microorganisms covers the latest amalgamation of the diversity of Mn biomining microorganisms, their biosolubilization mechanisms, and their role in natural manganese biogeochemical cycling. The book demonstrates the role of microorganisms as applied to manganese recovery from ores using bacteria. This new book provides an in-depth view of the latest trends in green mining, along with mechanistic views of biomining and bio recovery processes for both academic (undergraduate, postgraduate, doctoral students and lecturers/researchers) and industrial readers.

Fundamentals and Applications of Boron Chemistry highlights boron chemistry and its impressive potential across a range of fields. The book includes foundational information, current developments and applications in energy, medicinal chemistry and materials chemistry. Beginning with an introduction which outlines physical and chemical properties, the book then discusses advances in boron coordination chemistry and key fields of application. The latest developments and catalysts in organic reactions are also reviewed, along with updates on novel emerging boron-containing materials and their potential applications in areas such as hydrogen storage, in materials with special optical activity, and in boron-based drugs and therapies. Outlines the foundational principles and properties of boron chemistry Highlights developments in the application of boron chemistry across key areas, including catalysis, sustainable energy, materials development and pharmaceuticals Encourages and supports researchers in developing future applications based on boron''s chemical characteristics and activity

Innovations in Fermentation and Phytopharmaceutical Technologies discusses recent advancements in the field of different bioprocessing aspects for the development of different reactors, fermented products and phytopharmaceuticals. Written by leading experts in the field, the book presents the basic principles of upstream processing techniques, advanced downstream process technologies, and recycling of by-products during formation/production of various fermented and phytopharmaceutical products. The informative chapters in the book outline an application-oriented path for academicians, researchers and scientists in the field of industrial fermentation technology and phytopharmaceutical production. Includes concepts and examples of bioreactors, fermentation processes, fermentative and phytopharmaceutical products Describes the application of concepts of product formation, product recovery and waste utilization Provides new updates of information on the technological aspects of upstream and downstream processes/equipment and their respective products

Microencapsulation in the Food Industry: A Practical Implementation Guide, Second Edition continues to focus on the development of new microencapsulation techniques for researchers and scientists in the field. This practical reference combines the knowledge of new and novel processing techniques, materials and selection, regulatory aspects and testing and evaluation of materials. It provides application specific uses of microencapsulation as it applies to the food and nutraceutical industries. This reference offers unique solutions to some very specific product needs in the field of encapsulation. This second edition highlights changes in the industry as a result of a field that has traversed from the micro scale level to nano-scaled encapsulation and includes two new chapters, one on regulatory, quality, process scale-up, packaging, and economics and the other on testing and quality control.

Biomaterials for Angiogenesis and Vasculogenesis covers the application of materials designed to encourage new blood vessel formation. Angiogenesis and vasculogenesis play an important role in tissue engineering and regenerative medicine research by promoting vascular networks inside engineered tissues and thereby increasing tissue healing and regeneration. However, researchers are faced with the challenge of finding suitable materials for improving angiogenesis and vascular formation in assays. This book reviews a broad range of biomaterials for the promotion of blood vessel genesis, from polymers and bioactive glass, to nanomaterial scaffolds and 3D angiogenic constructs. In addition, the book covers a variety of applications for biomaterials in tissue repair and regeneration, including cardiovascular regeneration, liver tissue engineering and much more. It will serve as a detailed reference for researchers in academia and industry, working in the fields of biomedical science and engineering, materials science, regenerative medicine and translational medicine. Introduces readers to the molecular and cellular basis of angiogenesis and vasculogenesis Helps researchers find suitable biomaterials to promote angiogenesis in engineered tissues and assays Describes a range of biomaterials and their properties, including glass-ceramics, nano-carriers, polymers, and more

Biomass Processes and Chemicals is written to assist the reader in understanding the options available for the production of chemicals from biomass. Petroleum-based and natural gas-based chemicals are well-established products that have served industry and consumers for more than one hundred years. However, time is running out and natural gas and petroleum are now being depleted. Thus, the need for alternative technologies to produce chemicals is necessary. Chemicals produced from sources are now coming into place for the establishment of a chemicals-from-biomass industry, hence this book covers these advancements. Introduces a variety of biomass feedstocks as sources of chemicals Includes accurate background science and technology for technological options Features a very thorough approach for topical matters Written in a highly structured way by a globally recognized authority in the field

Analytical Approaches for Reinforced Concrete presents mathematically-derived theories and equations for RC design and construction. The book applies deductive reasoning, logic and mathematics to RC. Laying out, deductively, the principles of RC, it encourages researchers to re-imagine and innovate using a solid conceptual framework. Sections consider the reasoning behind key theories, as well as problems that remain unsolved. The title presents key ideas in simple language and illustrates them clearly to help the reader grasp difficult concepts and develop a solid foundation, grounded in mathematics, for further study and research. The book is future-oriented, demonstrating theories that are applicable not only to conventional reinforced concrete members, but also to the envisaged structures of tomorrow. Such developments will increasingly require a deep, deductive understanding of RC. This title is the first of its kind, presenting a fresh analytical approach to reinforced concrete design and construction. Takes an analytical approach to reinforced concrete using mathematics and deduction Lays out the reasoning behind key theories and models in reinforced concrete design and construction Encourages researchers-new and established- to re-imagine and innovate using a solid conceptual framework Presents difficult concepts that are clearly and analytically presented with accompanying illustrations Looks forward to the use of reinforced concrete in the complex structures of the future

Finite Element Method: Physics and Solution Methods aims to provide the reader a sound understanding of the physical systems and solution methods to enable effective use of the finite element method. This book focuses on one- and two-dimensional elasticity and heat transfer problems with detailed derivations of the governing equations. The connections between the classical variational techniques and the finite element method are carefully explained. Following the chapter addressing the classical variational methods, the finite element method is developed as a natural outcome of these methods where the governing partial differential equation is defined over a subsegment (element) of the solution domain. As well as being a guide to thorough and effective use of the finite element method, this book also functions as a reference on theory of elasticity, heat transfer, and mechanics of beams. Covers the detailed physics governing the physical systems and the computational methods that provide engineering solutions in one place, encouraging the reader to conduct fully informed finite element analysis Addresses the methodology for modeling heat transfer, elasticity, and structural mechanics problems Extensive worked examples are provided to help the reader to understand how to apply these methods in practice

Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety.

Economic growth, security and sustainability across Europe are at risk due to ageing railway infrastructure systems. At present, the majority of such systems are aging and some have even reached their initial design lives. These issues align with a major challenge in civil engineering: how to restore and improve urban infrastructure and built environments. Policy, environmental and physical barriers must be addressed and overcome. The complex and interconnected nature of the problem means that there is a need for academia, industry, communities and governments to work collaboratively. The challenges posed by extreme events from natural and man-made disasters are urgent.Rail Infrastructure Resilience: A Best-Practices Handbook presents developed improvement methods for rail infrastructure systems, toward resilience to extreme conditions. It shows how best to use new information in the engineering design, maintenance, construction and renewal of rail infrastructure resilience, through knowledge exchange and capability development. The book presents the outcome of a major European research project, known as the RISEN project. RISEN aimed to enhance knowledge creation and transfer using both international and intersectoral secondment mechanisms among European Advanced Rail Research Universities and SMEs, and Non-EU, leading rail universities, providing methodological approaches and practical tools for restoring and improving railway infrastructure systems for extreme events. Edited and written by members of this project, this book will be essential reading for researchers and practitioners hoping to find practical solutions to the challenges of rail infrastructure resilience. Offers a best-practices handbook for rail infrastructure resilience from the leaders in the field Paints a holistic picture of the rail transport system, showing that infrastructure maintenance intervention can be enhanced through advanced monitoring systems and resilience design Presents rail infrastructure resilience and advanced condition monitoring, allowing a better understanding of the critical maintenance, renewal and retrofit needs of railways Considers how academia, industry, communities and governments can work collaboratively in order to tackle aggregated problems in rail infrastructure resilience Presents the findings from the RISEN project, the leading European project on enhancing knowledge creation and transfer of expertise on rail infrastructure resilience

Semiconductor Memories and Systems provides a comprehensive overview of the current state of semiconductor memory at the technology and system levels. After an introduction on market trends and memory applications, the book focuses on mainstream technologies, illustrating their current status, challenges and opportunities, with special attention paid to scalability paths. Technologies discussed include static random access memory (SRAM), dynamic random access memory (DRAM), non-volatile memory (NVM), and NAND flash memory. Embedded memory and requirements and system level needs for storage class memory are also addressed. Each chapter covers physical operating mechanisms, fabrication technologies, and the main challenges to scalability.Finally, the work reviews the emerging trends for storage class memory, mainly focusing on the advantages and opportunities of phase change based memory technologies. Features contributions from experts from leading companies in semiconductor memory Discusses physical operating mechanisms, fabrication technologies and paths to scalability for current and emerging semiconductor memories Reviews primary memory technologies, including SRAM, DRAM, NVM and NAND flash memory Includes emerging storage class memory technologies such as phase change memory

Handbook of Artificial Intelligence Techniques in Photovoltaic Systems: Modelling, Control, Optimization, Forecasting and Fault Diagnosis provides readers with a comprehensive and detailed overview of the role of artificial intelligence in PV systems. Covering up-to-date research and methods on how, when and why to use and apply AI techniques in solving most photovoltaic problems, this book will serve as a complete reference in applying intelligent techniques and algorithms to increase PV system efficiency. Sections cover problem-solving data for challenges, including optimization, advanced control, output power forecasting, fault detection identification and localization, and more.Supported by the use of MATLAB and Simulink examples, this comprehensive illustration of AI-techniques and their applications in photovoltaic systems will provide valuable guidance for scientists and researchers working in this area. Includes intelligent methods in real-time using reconfigurable circuits FPGAs, DSPs and MCs Discusses the newest trends in AI forecasting, optimization and control applications Features MATLAB and Simulink examples highlighted throughout

Handbook of Generation IV Nuclear Reactors, Second Edition is a fully revised and updated comprehensive resource on the latest research and advances in generation IV nuclear reactor concepts. Editor Igor Pioro and his team of expert contributors have updated every chapter to reflect advances in the field since the first edition published in 2016. The book teaches the reader about available technologies, future prospects and the feasibility of each concept presented, equipping them users with a strong skillset which they can apply to their own work and research. Provides a fully updated, revised and comprehensive handbook dedicated entirely to generation IV nuclear reactorsIncludes new trends and developments since the first publication, as well as brand new case studies and appendicesCovers the latest research, developments and design information surrounding generation IV nuclear reactors

Cell-Cell Signaling in Development, Volume 150 covers new approaches and topics surrounding the diversity of animals, with recognized species now in the millions. Remarkably, the many distinct morphologies in the metazoan biosphere are generated by only a small number of genetically-encoded signaling systems that organize cells into patterned tissues, principally, the Wnt, Hedgehog, Bone morphogenic protein, fibroblast growth factor, Notch/Delta, and planar polarity systems whose roles orchestrating morphogenesis are widespread and evolutionarily conserved. Users will find the latest information on these elegant systems, along with conceptual links to signaling in plants and ideas that are emerging from recent progress. Presents the newest information on signaling proteins of animal development Covers the processes that make and distribute signaling proteins Includes coverage of cell-cell interactions that pattern tissues

Medicinal Chemistry of Anticancer Drugs, Third Edition provides an updated resource for students and researchers from the point-of-view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. The new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer.Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point-of-view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references, reviews and primary literature.

From Pasteur to Post-Genomic Era: Key Milestones and Methods in Bacteriology brings experts together to highlight the importance of microbiology-discipline based teaching with its unique skills based approaches. The book discusses how microscope microbiology has received significant attention since microorganisms played a significant role in the advancement, as well as destruction of, mankind during incidences such as the black death. With the discovery of penicillin from a fungal culture, the beneficial role of microorganisms has been a major catalyst in the progress of biological sciences. Interestingly, there are fundamental aspects of microbiology that did not change since revelations of their identity dating back to the Pasteur era. This book details the progress made and milestones that have been set in the science. Emphasizes traditional and discipline-based teaching with a focus on microbiologyCombines pedagogy and the challenges faced in the post-genomic eraProvides examples from various parts of the world, including from the Pasteur Institute

Optics of the Moon presents methods for interpreting optics of surfaces on the Moon with complicated structures. For example, the book illustrates how phase-ratio techniques can lead to the detection of surface structure anomalies, describes polarimetric studies of the lunar surface and their use, and addresses many other questions relating to the regolith-like surfaces of the Moon, such as why the Moon looks like a ball at a large phase angle and like a disk in full moon, why the lunar surface has slight color variations, and why at large phase angles its polarization degree closely correlates with albedo. Includes case studies, maps and color figures to illustrate concepts with specific application to the moonPresents theories alongside experimental and observational data to support and describe modern techniquesCommunicates new approaches and methods related to the optics of surfaces on the Moon with complicated structures

Cardio-Hepatology: Connections Between Hepatic and Cardiovascular Disease provides a direct relationship between the cardiac and hepatic pathologies providing the link between the heart and liver and showing how liver diseases predispose to impairment in heart functioning and vice versa. Considering the growing number of patients living (and living longer) with heart failure and/or congenital heart disease, it is important to know when and how to test for liver disease in this population, how to interpret abnormal test results, and what management is appropriate. Coverage includes what should be done for patients to limit, avoid, or postpone the impairment in the liver functioning induced by heart diseases and the impairment in the heart functioning induced by liver diseases, on the basis of scientific-exposed evidence and pathophysiology knowledge. This comprehensive, extended review of the medical literature is perfect for researchers interested in the connection between cardiology and hepatology as well as clinicians making therapeutic decisions for patients suffering from heart or liver chronic diseases.

Digital Agritechnology: Robotics and Systems for Agriculture and Livestock Production describes how systems acquire and use data in livestock production and agricultural systems, and how researchers can extract and aggregate efficiencies. The origins of digital agritechnology are decades old, with robotic milkers available for over 20 years and GPS-based tractor controls existing for nearly 30. However, only a few capabilities of these sensing and control systems are used. This book addresses the need to educate agriculturists on the full usage scale of these arable and livestock systems. Features how-to guides on extracting and analyzing data from digital systems Describes quality standards for data security and transmission Focuses on state-of-the-art systems in livestock production, along with arable and indoor agriculture

Environmental Assessment of Renewable Energy Conversion Technologies provides state-of-the-art coverage in both non-fossil energy conversion and storage techniques, as well as in their environmental assessment. This includes goal and scope, analysis boundaries, inventory and the impact assessment employed for the evaluation of these applications, as well as the environmental footprint of the technologies. The book compiles information currently available only in different sources concerning the environmental assessment of sustainable energy technologies, allowing for the comparative assessments of different technologies given specific boundary conditions, such as renewable potential and other specific features of discussed technologies. It offers readers a comprehensive overview of the entire energy supply chain, namely from production to storage, by allowing the consideration of different production and storage combinations, based on their environmental assessment. Provides an overview of the environmental assessment process of renewable energy conversion and storage technologies Includes state-of-the-art approaches and techniques for the comprehensive environmental assessment of individual sustainable energy conversion and storage technologies and their applications Features comparative assessments of different technologies

Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists. Presents a comprehensive reference on the emerging field of neuromodulation that features chapters from leading physicians and researchers in the fieldProvides a cohesive presentation of neuromodulation technologies and interventionsContains 550 full-color pages that begin with an overview of the clinical phases involved in neuromodulation, the challenges facing therapies and intraoperative procedures, and innovative solutions for better patient careEmphasizes the fundamentals needed to embrace the neuromodulation field as a cohesive clinical entityExplores the use of electrical, chemical and mechanical interventions to heal and improve neurological deficitsCovers the promise of neurostimulation for chronic pain, epilepsy, Parkinson''s disease, and other disorders and diseasesFeatures developments in the field of neuromodulation since the first edition was published, including findings in lead, IPG and accessories

The Neuroscience of Autism provides a comprehensive accounting of autism spectrum disorders by integrating scientific findings from behavioral, cognitive and neurobiological research. The book begins by defining autism, identifying characteristics and prevalence, exploring its history, and then moving on to the cognitive and social bases of behavioral symptoms, the brain bases of behavioral and cognitive symptoms, and finally, intervention practices. It examines theoretical models such as weak central coherence, enhanced perceptual functioning, and the extreme male brain hypothesis. Finally, the book addresses the increased attention on the brain connectivity model of autism, looking at the synchronization of brain activity across different brain areas, the causal influence of a brain region on another, and white matter cable connections in the brain.

"Thermodynamic Tables to Accompany Modern Engineering Thermodynamics".

Global concern for energy security and environmental protection has put great emphasis on the search for alternative energy sources, particularly for the transport sector. Biofuels have emerged as a highly promising source of alternative energy. This title provides information on the status of biofuel production and related aspects.

Features scientific content written at a level comprehensible for wine professionals as well as advanced students. This title includes information on production and spoilage issues, the microbial groups relevant for wine production and microbial wine safety. It presents methods of studying the microbiology of wine.