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  • af Thorsten Buzug
    1.273,95 kr.

    This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects.

  • af Alfred Mertins, Heinz Handels, Stephan Klein, mfl.
    1.273,95 kr.

  • af Clara Pfäffle
    1.128,95 kr.

    In this book, a functional contrast of the human neurons in the retina based on the phase information of the optical coherence tomography (OCT) signal is presented. To gain access to the phase information, data is recorded with a full-field swept-source OCT. By axial and lateral parallelization of the data acquisition, the influence of motion artifacts on the phase can be minimized, so that the phase information is available for an analysis of the physiological changes of the sample.In this book, the technical implementation of full-field imaging, the algorithms necessary for the phase analysis, such as registration, segmentation, numerical aberration and dispersion correction, and the phase analysis itself are presented. This recording technology, combined with the numerical processing, was then used to detect functional changes in the neurons of the retina. Functional changes in both the photoreceptors and the inner plexiform layer (IPL) were detected and the functional contributions of different cell types to the phase change were differentiated.

  • af Anselm von Gladiß
    1.158,95 kr.

  • af Robert Wendlandt & Arndt-Peter Schulz
    1.163,95 kr.

    This congress volume compiles the contributions of the Bone Innovation Summit as well as an overview of current research results in the field of orthopedics and traumatology from the last three years.The Northopedics, BONEBANK and BFCC projects, launched three years ago, focus on improving fracture treatment in northern Germany, the Danish-German border region and the Baltic Sea countries. The projects address the different perspectives of patients, physicians, clinics, researchers, industry and regulatory authorities on improving fracture care.The overall aim of the projects is to foster innovation through register research and to improve the funding conditions for research projects. In addition, a number of approaches for the harvesting of stem cells for therapies were evaluated and concepts for new medical devices were developed.

  • af Jens Horstmann
    878,95 kr.

  • af Alfred Mertins, Heinz Handels, Stephan Klein, mfl.
    1.033,95 kr.

    This volume shows how new approaches and methods in medical engineering and medical informatics can advance medicine, health, and health care. The Student Conference is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics, biomedical engineering, and auditory technology present results of their recent research projects.

  • - Book of Abstracts
    af Alexey Tonyushkin
    1.033,95 kr.

    The 9th International Workshop on Magnetic Particle Imaging took place in New York, March 2019. Since the first workshop in 2010, the International Workshop on MPI (IWMPI) has been the premier forum for researchers working in the MPI field. The workshop aims at covering the status and recent developments of both the instrumentation and the tracer material, as they are equally important in designing a well performing MPI system. The main topics presented at the workshop include hardware developments, image reconstruction and systems theory, nanoparticle physics and theory, nanoparticle synthesis, spectroscopy, patient safety, and medical/research applications of MPI: www.iwmpi.org.

  • - 9th Conference on Medical Engineering Science, 5th Conference on Medical Informatics, 3rd Conference on Biomedical Engineering, and 2nd Conference on Auditory Technology
     
    1.063,95 kr.

  •  
    1.268,95 kr.

    Additive manufacturing, often referred to as 3D printing, has long since proven its suitability for everyday use. However, many questions remain unanswered for use in medicine. Complex melting and hardening processes take place during the layer-by-layer construction of medical devices from liquid or solid materials, the physical-chemical modelling of which is often still pending, so that a discussion forum is to be given at AMMM on topics relating to the achievable precision and the expected technical properties of the medical devices produced in this way. Questions about the precision and interaction of the printed materials with their future application matrix are important for all industries. However, these requirements are of particular interest in the medical environment, where biological compatibility and long-term stability are of particular importance. Medical technology companies are also faced with the question of whether this modern manufacturing technology should only be used in prototype and individualized sample development or also in series production. Costs and benefits have to be assessed very individually. AMMM 2019 will focus on these questions, with particular emphasis on the medical device regulation of patient-specific devices.

  •  
    358,95 kr.

    National und international ausgewiesene Expertinnen und Experten auf dem Gebiet der Vaskulitisforschung, Diagnostik und Behandlung werden zu neuen wissenschaftlichen Erkenntnissen, aktuellen Therapieansätzen, neuen Studien und Behandlungsansätzen berichten. Die 17. bundesweite Vaskulitis-Tagung wird in zwei Jahren im Sommer 2021 wieder in Lübeck stattfinden.Alle Informationen zur Tagung werden im Internet dargestellt:www.tagung.vaskulitiszentrum.org

  • af Annette Bretin
    1.138,95 kr.

    Patient-specific finite element analysis of bone is a promising method for surgical planning, implant design and the prediction of bone remodelling or fracture risks, yet the assignment of material properties is challenging. Bone is a complicated structure with direction-dependent, inhomogeneous material properties, influenced by compositional, geometrical and architectural aspects. This volume focuses on a density-based assignment of orthotropic bone properties. Elasticity-density relationships in homogenized femoral zones were examined to evaluate the orthotropic density-dependence of the nine elastic material constants locally. Cortical bone samples were tested in compression and torsion tests using videoextensometry to determine the elastic constants. The elastic properties of cancellous bone were predicted by micro finite element analysis. All determined constants were correlated to the radiological bone mineral density of each sample, which was determined by quantitative computed tomography. The trabecular eigensystem was investigated for each cancellous zone to assign the mean directionality of trabecular fabric. The results can be beneficial for density-based orthotropic material assignment in femoral patient-specific finite element models.

  • - Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake inside Pancreatic Tumor Cells and in vitro Efficacy
    af Ulrich Engelmann
    1.033,95 kr.

    Magnetic fluid hyperthermia (MFH) uses magnetic nanoparticles (MNP) to transform the energy of an alternating magnetic field into heat via magnetic relaxation. This enables organ-confined cancer treatment by delivering cell-damaging temperatures higher than 43°C inside tumors. However, MNP-cell interaction restricts MNP mobility and causes MNP agglomeration, severely limiting the MNP heating behavior. Based on in vitro experiments, this book addresses the applicability of MFH to pancreatic tumor cells and discusses optimizations of intracellular MNP heating for clinical application. The impact of MNP-cell interaction on heating efficiency is quantified and compared to MNP systems mimicking intracellular conditions. Besides, Monte-Carlo simulation of MNP magnetic relaxation is used to predict optimal field parameters and MNP properties to maximize MFH efficiency under medical constraints.

  •  
    1.118,95 kr.

    This book concludes the results of the 2nd symposium on functional or regulatory autoantibodies targeting G-protein-coupled receptors (GPCRs) in Lübeck in 2018. GPCRs are involved in a variety of physiological and pathophysiological processes. So far, much effort has been made on anti-GPCR drug discovery with a focus on the development of small molecules for the treatment of cancer, infection, metabolic disorders or inflammatory diseases. Recently, functional autoantibodies against GPCRs were identified in healthy donors and were found to be dysregulated in various diseases. They are associated with pathogenesis, uncovering a potential new field of therapeutic intervention. Thus, the aim of the symposium in 2018 was to combine the current knowledge about the role of anti-GPCR ab in different pathologies, their mode of action and state-of-the-art research techniques to identify common fundamental pathways that can be transferred to other disease entities with similar manifestations.

  • af Andre Mastmeyer
    1.138,95 kr.

    In the context of individualized medicine and in the age of 4D imaging, current research covers the plausible personalized, visuo-haptic Virtual Reality (VR) immersion for training and planning of puncture interventions. In this book, this subject is first overviewed and presented regarding the technical details by selected English scientific publications.The patient model results from a mostly automatic procedure for the segmentation of puncture-relevant organs and structures. For increased realism, the influence of simulated respiratory movement extracted and modeled from 4D-CT images was also taken into account. Based on these modeling steps, innovative, efficient GPU algorithms for volume-based visuo-haptic simulation and the direct volume rendering of physiological processes of the patient model were proposed. For a time-invariant patient model, the local consideration of space bending mathematically introduced by an inverted movement model leads to efficient visuo-haptic rendering methods: Simulated imaging of ultrasound, fluoroscopy, the stereoscopic two-eye perspective and haptics are elaborated. This approach eventually allowed the immersive interaction of the ultrasound probe and puncture needle with breathing virtual patients.The methods were developed in cooperation with clinical partners and successfully applied and evaluated in a user study. The medical potential of the methods presented in this work lies in the future in the pre-operative and personalized preparation of interventions. Specifically, for the described application of liver punctures, the number of needle repositionings could be significantly reduced, relieving the patient and saving treatment costs.

  • af Christian Kaethner
    1.163,95 kr.

    Magnetic Particle Imaging (MPI) ist ein bildgebendes Verfahren, das auf Basis hochfrequent-variierender Magnetfelder eine Visualisierung von magnetischen Tracer-Materialien ermöglicht. Aufgrund einer einzigartigen Kombination aus hoher örtlicher und zeitlicher Auflösung bei gleichzeitigem Vorliegen einer hohen Sensitivität bietet MPI ein hohes Potenzial im Hinblick auf die Weiterentwicklung medizinischer Diagnose- und Therapieansätze. In dem vorliegenden Werk werden neuartige Konzepte vorgestellt, die sich sowohl einer effizienten Nutzung als auch einer Erweiterung des Messfeldes in MPI widmen. Neben einer leistungseffizienten Erzeugung von Magnetfeldern zur Erweiterung des Abtastbereiches wird sich mit der Charakterisierung der Bildgebungstrajektorie befasst. Die hierbei gewonnenen Erkenntnisse können anschließend in die MPI-Systemkalibrierung überführt und zur Datenreduktion genutzt werden. Bezüglich der Strategien zur Erweiterung des Messfeldes wird sich in diesem Werk auf Ansätze in axialer Richtung fokussiert und ein Verfahren vorgestellt, das es in Anlehnung an die Computertomographie erlaubt, eine theoretisch unbeschränkte axiale Messfeldvergrößerung zu erreichen.

  • af Heinz Handels & Stephan Klein
    1.058,95 kr.

    The Student Conference on Medical Engineering Science, Medical Informatics and Biomedical Engineering is an annual event at the BioMedTec Science Campus Lübeck. The Congress is organized by the Universität zu Lübeck and the University of Applied Science Lübeck. Master students of programs related to medical engineering science, medical informatics and biomedical engineering present results of their recent research projects.Chapters:1. Biomedical Engineering2. Biomedical Optics3. Biochemical Physics4. Signal Processing5. Image Processing6. Medical Imaging7. Safety and Quality8. E-Health

  • af Matthias Weber
    1.163,95 kr.

    Magnetic Particle Imaging (MPI) ist ein neuartiges Bildgebungsverfahren, das es erlaubt, eine dreidimensionale Verteilung von superparamagnetischen Eisenoxidpartikeln in Echtzeit zu visualisieren.Das vorliegende Werk stellt drei neuartige Instrumentierungen für MPI-Systeme vor, die auf einer feldfreien Linie (FFL) basieren. Anhand der Systeme wird gezeigt, dass es mit Hilfe der FFL-Technologie möglich ist, Echtzeitfähigkeit, geringe Systemkomplexität und hohe räumliche Auflösung zu realisieren. Mittels einer elektronisch rotierenden FFL wird zunächst gezeigt, dass eine Partikelverteilung in Echtzeit (50 Bilder pro Sekunde) untersucht werden kann. Anschließend wird ein Konzept vorgestellt, das die Bildgebung mit Hilfe einer mechanisch rotierenden FFL realisiert. Schlüsseleigenschaft dieses Systems sind eine äußerst geringe Komplexität und geringe infrastrukturelle Anforderungen. Schließlich wird eine neuartige Magnetanordnung eingeführt. Dieses Konzept vereint hohe räumliche Auflösung, geringe Komplexität und Echtzeitbildgebung.

  • af Mandy Ahlborg
    813,95 - 873,95 kr.

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