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This reprint focuses on older adults, who represent a large portion of patients with acute coronary syndromes and cardiovascular diseases in general but are seldom included in randomized clinical trials. The articles in this reprint offer evidence to assist clinical decision making and guide clinicians worldwide in problems with everyday clinical implications, which often result in the mis- or undertreatment of this large population of fragile individuals.

This Special Issue serves as a compendium of the most recent advancements in the field of multiple-input multiple-output (MIMO) radars, including a wide array of high-potential research domains. These areas span across both theoretical frameworks and practical applications. Its key focal points include MIMO radar waveform design, MIMO signal detection, parameter estimation and imaging, as well as MIMO clutter and jamming suppression techniques. The primary objective of this Special Issue is to stimulate the generation of innovative ideas while fostering enhanced communication and collaboration opportunities among students and researchers actively involved in the field of MIMO radar research.

Glaucoma is an optic neuropathy that is characterized by the death of retinal ganglion cells and leads to the progressive loss of vision. This Reprint presents the new frontiers in "Glaucoma Treatment". It includes pharmaceutical and surgical treatments.

Point clouds are deemed to be one of the foundational pillars in representing the 3D digital world, despite irregular topologies among discrete points. Recently, advancements in sensor technologies that acquire point cloud data for flexible and scalable geometric representation have paved the way for the development of new ideas, methodologies, and solutions in countless remote sensing applications. State-of-the-art sensors are capable of capturing and describing objects in a scene by using dense point clouds from various platforms (satellites, aerial, UAVs, vehicle-borne, backpacks, handheld, and static terrestrial), perspectives (nadir, oblique, and side view), spectra (multispectral), and granularity (point density and completeness). Meanwhile, the ever-expanding application areas of point cloud processing have already covered not only conventional domains in geospatial analysis but also manufacturing, civil engineering, construction, transportation, ecology, forestry, mechanical engineering, etc. Readers can learn about the latest innovative technologies for generating, processing, and analyzing point cloud data from these contributions, which helps to understand the challenges faced by point cloud data and develop new 3D applications.

The worldwide spread of COVID-19 in 2020 posed severe challenges in the realm of public health and also resulted in social limitations, such as on access to parks and other public open spaces. The restrictions on movement and lockdowns that were imposed by many governments had profound implications, altering not only the frequency and purpose of urban green space visitation, but also the social and psychological effects which such green spaces had on citizens. This Special Issue gathered recent studies on how the need, perception and usage of green spaces have been impacted by the pandemic and the restriction measures, in order to provide insights and guidance for administrators and policy makers to manage future crisis situations. A total of 15 papers examine the effects of COVID-19 in different countries and even continents, offering various research methodologies and reflections on the role of urban green spaces in daily life. One of the recurring themes is that there is a general need to guarantee equitable access to these valuable resources, especially in times of societal disruption. The opportunities for relaxation, social interaction and spiritual regeneration are indeed important benefits that such natural amenities can offer, but they are very much dependent on the design and particular qualities of the space, which may decisively influence the level of satisfaction and engagement by users. It is our hope that by encouraging a communal discussion on the planning and management of urban green spaces, we can increase the resilience of both our cities and the natural environment on which they depend.

Hereditary Hemorrhagic Telangiectasia (HHT), or Rendu-Osler-Weber syndrome, is a dominantly inheritable rare disease with a prevalence of 1:5,000 - 10,000 people. The diagnosis of HHT, as a rare disease, follows the Curaçao Diagnostic Criteria: Nosebleeds (epistaxis), whether spontaneous or recurrent; (multiple) telangiectases at characteristic sites, including the lips, oral cavity, fingers and nose; Internal lesions: arteriovenous malformations (AVMs) or telangiectases in the stomach, lungs, liver, brain and spinal cord; Family history: a first-degree relative with HHT, according to these criteria. When a patient meets at least three of these criteria, it is considered definite that they have HHT. Nowadays, three subtypes of HHT have been identified. HHT type 1 refers to mutations on the endoglin gene ENG; HHT type 2 refers to mutations on the activin A receptor-like type 1 (ACVRL1) gene; and the third one, named juvenile polyposis-hereditary hemorrhagic telangiectasia (JPHT or JPHHT) overlap syndrome, refers to mutations on the gene MADH 4. There are two other subtypes (HHT-3 and 4) in which the mutations have not yet been completely identified, but they are known to be located on the 5q31.3-q32 and 7p14 chromosomal regions, respectively.

Food is subjected to various treatments and processes before human consumption, which have an effect on the food's shelf life, nutritional value, and sensory qualities. This Special Issue reprint contains studies regarding cold storage, refrigeration, freezing, fermentation, cold plasma, cooking, shaping, reforming, and packaging. These methods were applied during the processing of vegetables, fruit, dairy, oils, meats, seeds, marine foods, beverages, and other food items. This Special Issue reprint is designed for food scientists, technologists, food industry workers, dietitians, and nutritionists, as well as research scientists.

The Internet's great success has been essentially based on the simplicity and versatility of its TCP/IP architecture, as it imposes almost no restrictions on either the underlying network technology or the data being transmitted. In essence, applications built on top of TCP/IP get a point-to-point channel that can be used to transmit arbitrary information. This approach has served quite satisfactorily for many years, but it is no longer well suited to some of the new communication paradigms now being used on the Internet. Nowadays, most applications running on top of the Internet are no longer interested in using a point-to-point channel to exchange traffic between two endpoints. In contrast, what they want is to obtain some piece of information that is available in the network somewhere. The current use of load balancers and cache overlay networks is an interim solution to address this mismatch between the network communication model and the needs of applications, but such a solution suffers from significant shortcomings. Information-centric networks (ICNs), particularly Named Data Networking (NDN) and CCNx, offer a service where users can directly obtain information, regardless of location. This service suits current network uses and can provide the traditional point-to-point communication service if desired. This Special Issue highlights and presents recent advances in different problems related to using information-centric network architecture.

A masterpiece in the realm of polymer science, "Advanced Science and Technology of Polymer Matrix Nanomaterials" presents a comprehensive exploration of the cutting-edge advancements in polymer matrix nanomaterials. This reprint delves into the remarkable progress made in the synthesis, characterization, and applications of these materials, showcasing their immense potential to revolutionize various industries. With meticulous attention to detail and a profound understanding of the subject matter, this seminal work provides a concise yet comprehensive overview of the field. From the fundamental principles to the latest research breakthroughs, it covers a wide spectrum of topics, including nanocomposites, nanofibers, and others. The description of the Reprint serves as a concise summary, intended to capture readers' attention and ignite their curiosity. It serves as a testament to the significant contribution this reprint makes in the field of polymer science, unveiling new avenues for scientific exploration and technological innovation.Through its eloquent prose and meticulous analysis, "Advanced Science and Technology of Polymer Matrix Nanomaterials" establishes itself as an indispensable resource for scholars, scientists, and professionals seeking to deepen their understanding of this exciting and rapidly evolving field.

This reprint brings together some recent advances in the sustainable re-design of natural waste and biomass in different material productions for both textile and non-textile applications. These include a wide array of topics, such as the following: the use of textile waste fibers, i.e., wool as a fertilizer to promote plant growth; the potential of cellulose textiles from hemp biomass; the use of green wood adhesives from sustainable proteins; optimization of the pyrolysis process of biomass; the use of natural wastes in composites preparation, including cellulosic waste as well as leather waste; dye adsorbents prepared from cellulosic wastes; some new methods of environmentally friendly dyeing; and imparting functionality to textiles by using natural ingredients.

Metallic and ceramic materials play a significant role in the development of modern science and technology. They have a broad range of applications in various engineering fields. A proper manufacturing process, heat treatment, and forming are three main processes that can lead to obtaining metallic and ceramic materials which are created mainly to discover new or improved materials of construction, e.g., due to their strength properties. The main aim of this Special Issue was to publish original review and research articles from a wide range of research fields involving the manufacturing, heat treatment, and forming processes of metallic and ceramic materials.

Legume crops are grown worldwide and provide a major source of protein, oil, carbohydrates, dietary fiber, and dietary minerals. Legume crops also play an important role in international trade. Genetic improvement has been a key to the growth of crop production, and it continuously contributes to sustainable agriculture and food security. Presently, plant genetic improvement is in the middle of evolution from field-based traditional breeding to a new era of application of multiple novel techniques such as marker-assisted selection, genomic prediction, and gene editing, which are integrated with conventional methods in practical breeding. This Reprint contains fifteen research articles and a review paper that address a wide range of research topics in legume crops. The research involved all the traits of importance, including yield, quality, resistance to pests and diseases, and abiotic stresses. This Reprint can be used as a source of information for future work.

Humans and animals may be exposed on a continuous daily basis to a mixture of environmental contaminants that may cause adverse consequences. This Topic focuses on environmental pollutants including heavy metals, pesticides, nanoparticles, micro-nanoplastics, indoor air pollutants, pharmaceuticals, and industrial toxicants with effects on human health, risk assessment, and the relationship between various diseases and environmental pollutants. The aim of this Topic is to present a comprehensive overview of various studies carried out with in vivo and in vitro model organisms and the potential risks posed by environmental pollutants to human health. In this Topic, 20 original articles, 6 reviews and 1 communication are collected, with a particular focus on alcohol-based hand sanitizers, polycyclic aromatic hydrocarbons, monochromatic light pollution, paraben as an endocrine disruptor, heavy metal pollution attributed to the antimony and arsenic found in mines in soil, water, and sediments, groundwater with high fluoride levels, the transmission of viruses due to the heating, ventilation, and air conditioning systems of urban subways, chronic home radon exposure, organotin compounds, heavy metal pollutants, polypropylene microplastics, ventral body wall defects in chick embryos, microcystin-LR as an aquatic toxin, N-nitroso compounds, methylmercury as a global pollutant, triazine herbicides, persistent organic pollutants, bisphenol A and trace metals, autophagy, nano- and micro-sized polystyrene particles, tributyltin as an environmental contaminant, polybrominated diphenyl ethers, and per- and polyfluoroalkyl substances.

This reprint is a collection of original research papers that cover recent developments in the field of microstructure engineering of metals and alloys. Microstructure and its engineering are of high scientific and industrial interest since it is among the major factors that affect the properties and performance of metals and alloys. This reprint covers studies on microstructure effects on ferrous and non-ferrous alloys.

This Special Issue, titled "Problems during the Design and Testing of Instrument, Special and Power Transformers", presents and disseminates the latest developments in the theory, design, modeling, and laboratory testing of all types of transformers. The scope includes design calculations and diagnostics of various types and structures of 1- and 3-phase power transformers, special transformers, and measurement transformers with various applications. Design requirements concern exploitation and optimal design methodologies, advanced device modeling methods, and technical research methods.

The rapid development of polymer science has brought convenience to people's lives. At the same time, more and more waste is produced from the use of polymer products, which causes harm to the environment. In order to protect the living environment, scholars have researched and developed the recycling technology of waste plastics. On the other hand, many contemporary medicines contain polymers as a component, so a detailed study of the decay of such polymers, at least to their exit from the body, is required.

The spreading antibiotic resistance of bacteria is one of the most important challenges of modern medicine, and a search for methods that could replace conventional treatments of bacterial infections is urgently needed. Bacteriophage therapy is considered one of the most important alternatives to commonly applied antibacterial strategies.This Special Issue, titled "Bacteriophage Therapy: Recent Developments and Applications of a Renaissance Weapon", collected eleven articles focused on different aspects of phage therapy. It includes five original articles, two case studies, and four reviews presenting research on the application of phages against pathogens posing a serious threat to human health, such as Salmonella enterica, Pseudomonas aeruginosa, Vibrio cholerae, and Staphylococcus aureus. The published articles also relate to the practical aspects of phage application, such as the development of modern phage carriers or the employment of mathematical tools for predicting bacteriophage features and their antibacterial potential. Furthermore, an important research topic discussed in this Special Issue is the application of phages in food safety, where phages could potentially replace routinely used antibacterials.

Parkinson's disease (PD) is the second most common neurodegenerative disorder, and although it is usually considered as a disorder that only affects movement, a broad spectrum of non-motor symptoms (NMSs) can be observed in PD patients. Although the realities of the disease vary enormously from patient to patient, almost all of them have one or more NMS. In fact, a wide range of behavioural, neuropsychiatric, and physical symptoms frequently play a primary role in managing the disorder and constitute a major disease burden for patients and caregivers.The current reprint includes a compilation of published articles about NMSs in Parkinson's disease and potential treatment strategies.

This collection aims to emphasize the ever-changing nature of sport. In doing so, the reader is moved away from the traditional routes of organized and elite sport to consider how sport and other physical activities evolve and shift in response to and in anticipation of broader social changes. Included within are contributions stemming from the idea of "rethinking sport" that address the notion of training as part of cancer treatment, the development of informal and lifestyle sports, parkour activities in James Bond movies, and the phenomenon of Timbersports. This collection has a further specific focus on topics related to "social issues" and how sport may counter or create inequalities. This anthology includes chapters that engage in analyses of several of these topics, such as sexual abuse, drug abuse, health promotion programs, trauma-informed coaching, inclusion and exclusion mechanisms in gym culture, the long-term social impact of sport gentrification, and human rights and racialization in sport. Built on the work of established and emerging scholars, this collection includes research from a variety of disciplines including sociology, sport science, social work, cultural studies, gender studies, and more.

Agriculture is facing the challenge of the transition to sustainability under a changing climatic scenario. Understanding the complexity of the agroecosystems can favor research on innovative agronomic practices to guide this change. The optimization of the spatiotemporal combination among plants in farming systems (crop sequence and intercropping), the exploitation of the different forms of biodiversity at the soil and plant levels, the increase in the use efficiency of native resources (radiation and rainfall, N2, CO2, H2O, etc.), and the reduction in the dependence on external energy input (soil tillage, agrochemicals, and mineral fertilizers) represent the driving force behind this paradigmatic change. This approach will ensure the enhancement of the territorial vocation in productive and qualitative terms, whilst also promoting several ecosystem services from carbon sequestration to landscape ecology. The scientific community is called to take up this challenge. The present reprint is focused on the recent advancements in the broad scientific area of field crops in order to identify strategies and tactics calibrated site-by-site for eco-friendly and efficient agronomic management. This is a reprint of the closed Special Issue "Cropping Systems and Agronomic Management Practices of Field Crops" edited by Prof. Umberto Anastasi and Dr. Aurelio Scavo, which collected 37 research articles and 2 reviews related to the recent advancements in the wide scientific area of field crops.

As they have become inherently ingrained in our society and societies worldwide, the noxious disparities in health-risk behaviors and health require far-reaching investigation, supporting greater uniformity across groups. The deep-seated nature of discrimination, stigmatization, and marginalization in our social structure means that the human rights and health of too many individuals suffer, while social injustice and inequity persist. Health and illness are linked to social structure by the lack of health information and access and health-risk behaviors, such as use of tobacco, alcohol, and other substances; lack of adequate physical exercise; and obesity. The after-effects of health-risk behavior are also found in the perpetration of violent and other criminal behaviors. The reprint of this Special Issue, titled "Disparities in Health-Risk Behaviors and Health", is a comprehensive collection of novel papers that identifies and discusses the (1) social determinants of disparities in health-risk behaviors and health, (2) social mechanisms responsible for these persistent disparities, and (3) policies and practices recommended for reducing disparities. These papers were grounded firmly in the understanding that gender, racial/ethnic, immigration, LGBT, and socioeconomic statuses contribute to an individual's health status.

This Special Issue presents a collection of recent advancements in sediment transport research and hydraulic engineering that contribute to filling the knowledge gap in morphodynamic processes at different scales, with an outlook towards innovative river engineering approaches, monitoring systems, available technologies, and management practices tackling rapidly changing environmental conditions.

The extracellular matrix (ECM) is a dynamic scaffold structure that surrounds all cells in the body and provides structural integrity as well as dynamic signaling cues. These ECM cues influence many aspects of cellular function and phenotype, including cell death, proliferation, cell fate specification, and tissue morphogenesis. Therefore, it is critically important to understand the impact of ECM interactions on disease pathology, tissue engineering, and tissue regeneration. These original research and review articles illustrate the importance of ECM interactions on fundamental cell behavior. Using bioengineering and biomaterial strategies, the effects of the ECM on cell behavior and function can be systematically studied. Cell-ECM interactions are further explored in a variety of tissue and disease models, including cardiovascular, musculoskeletal, lymphatic, and skin applications. These articles were published from 2022 to 2023 in Bioengineering.

The agricultural sector is undergoing a profound transformation derived from the introduction of new technologies and tools from industry 4.0, giving rise to what has been called Agriculture 4.0. This Reprint contains a selection of some interesting recent advances in this field, including new techniques for remote crop sensing and agricultural machinery, the development of novel vision and deep learning algorithms, advances in aquaculture technologies, and a review on the state of the art in Horticulture 4.0.

As people become more environmentally aware and recycle, the reuse of waste materials and the application of sustainable techniques in the construction field have become popular. This reprint collates new green and sustainable infrastructure construction materials, including cement and asphalt concrete, biomass, and composite infrastructure materials. This collection should be used as a guidance for the future field application of new techniques for the improved environmental sustainability of infrastructure constructions.

Recently, the trends of a circular economy and sustainability have driven nanotechnology towards the development of novel and innovative applications in the food packaging sector, which is rather recent compared with their use in biomedical and pharmaceutical applications. Bioactive films and coatings based on natural biopolymers such as chitosan, sodium alginate and gelatin and containing antioxidant and antimicrobial agents such as micro- and nanoemulsions of phytochemicals and nanostructured materials such as quantum dots, ZnO nanoparticles, nanoclays, silicas, zeolites and activated carbons, are finding application in various sectors of the food industry, especially in the development of novel edible, active packaging films and coatings. These bioactive films and coating materials enhance solubility, improve bioavailability, facilitate controlled release, and protect bioactive components during manufacture and storage. This Issue intends to provide an overview of bioactive gel films and coatings applied in active food packaging.

This reprint, entitled "Application of data-driven method for HVAC System", is dedicated to providing an overview of the latest achievements in the application of data-driven methods for HVAC systems. Topics of interest include, but are not limited to, the following: fault detection and diagnosis of HVAC systems; energy consumption prediction; model predictive control; data mining and analysis of HVAC systems; data mining and analysis of building environment; energy conservation; energy saving.

This Special Issue reprint includes one review and fifteen research articles. The review by Palyanova et al. (2023) summarized the available information on the palladian gold and proposed classifying the types of deposits based on the fineness, content, and set of impurities in palladian gold and minerals intergrown with it. Fifteen articles focused on the typomorphic features of native gold from gold deposits in Russia, India, Chile, Scotland, and Canada. This Special Issue aims to identify and generalize the reasons for variations in the compositions of native gold. I hope all the articles in this Special Issue will be helpful and valuable resources for anyone who is interested in native gold and gold deposits. I thank the Authors and Reviewers for their efforts and contributions. I am also grateful to the Editor-in-Chief, Editors and Assistant Editors of Minerals for their help.

This Special Issue is dedicated to Dr. Patricia Somers (22 April 1949-10 March 2023). Pat was a proud mother, feminist educator, devoted colleague, and beloved mentor for her students. Above all, she advocated for the underserved and minoritized, including investing time in her students who were up against considerable institutional odds. Pat was also a driving force for social justice in the United States, Brazil, and across the world, as her scholarship prioritized giving voice to the voiceless and advocating for racial and gender equity. As an editorial team, we honor and celebrate Dr. Somers' vibrant and impactful life with this Special Issue, in the hopes that future generations of educators follow her lead and promote diversity, equity, and inclusion. Rest in peace and in power, Pat. We will miss you always.

Terrestrial and marine environments are inexhaustible sources of compounds and active extracts which have been employed in medicine since ancient times. The aim of this reprint is to collect new approaches around compounds and extracts isolated from natural products and their biological activity, with a focus on anti-inflammatory pathways. Thus, this reprint compiles full original papers and reviews articles published during 2023 in a Special Issue of Life, titled "Inflammation and Natural products". The publications within this reprint are focused on secondary metabolites of plants demonstrating significant antioxidants and anti-inflammatory properties, among others, and clinical relevance in various pathological conditions. It also includes reviews that focus on natural therapies for topics such as arthritis, lung diseases, neuroprotection, skin photoprotection, and the impact of gender in the use of medicinal plants in relation to vascular diseases. The reprint of this Special Issue will serve as a reference text for researchers and academics, as well as those studying natural products and their pharmacological activities.