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This practical guide bridges the gap between general cloud computing architecture in Microsoft Azure and scientific computing for bioinformatics and genomics. You'll get a solid understanding of the architecture patterns and services that are offered in Azure and how they might be used in your bioinformatics practice. You'll get code examples that you can reuse for your specific needs. And you'll get plenty of concrete examples to illustrate how a given service is used in a bioinformatics context.You'll also get valuable advice on how to:Use enterprise platform services to easily scale your bioinformatics workloadsOrganize, query, and analyze genomic data at scaleBuild a genomics data lake and accompanying data warehouseUse Azure Machine Learning to scale your model training, track model performance, and deploy winning modelsOrchestrate and automate processing pipelines using Azure Data Factory and DatabricksCloudify your organization's existing bioinformatics pipelines by moving your workflows to Azure high-performance compute servicesAnd more

When it comes to building user interfaces on the web, React enables web developers to unlock a new world of possibilities. This practical book helps you take a deep dive into fundamental concepts of this JavaScript library, including JSX syntax and advanced patterns, the virtual DOM, React reconciliation, and advanced optimization techniques. By becoming fluent in React, you'll quickly learn how to build better web applications. Author Tejas Kumar helps you explore the depths of React in plain English, without the typical software engineering jargon, so you can more easily understand how this JavaScript library works. You'll learn how to write intuitive React code that fully understands the nuances and layers of React, unlocking a whole new level of fluency. You will: Understand how React works at a deeper level Write React apps while optimizing them along the way Build resilient React applications that work well at arbitrary scale Create React applications for other platforms adjacent to the web and mobile devices Know when to reach for different mechanisms exposed by React, such as reducers versus state versus refs

"This book teaches Git in a simple, visual, and tangible manner so that you can build a solid mental model of how Git version control works. Through the use of color, storytelling, and hands-on exercises, you will learn to use this tool with confidence ... Learning Git is ideal for anyone who needs to use Git for personal or professional projects: coding bootcamp students, junior developers, data professionals, and technical writers"--

"With this practical guide, power users and developers will discover ways to resolve everyday challenges by building end-to-end solutions with the Microsoft Power Platform. Author Jason Rivera, who specializes in SharePoint and the Microsoft 365 solution architecture, provides a comprehensive overview of how to use the Power Platform to build end-to-end solutions that address tactical business needs. By learning key components of the platform, including Power Apps, Power Automate, and Power BI, you'll be able to build low-code and no code applications, automate repeatable business processes, and create interactive reports from available data"--

"Cybersecurity is broken. Year after year, attackers remain unchallenged and undeterred, while engineering teams feel pressure to design, build, and operate 'secure' systems. Failure can't be prevented, mental models of systems are incomplete, and our digital world constantly evolves. How can we verify that our systems behave the way we expect? What can we do to improve our systems' resilience? In this comprehensive guide, authors Kelly Shortridge and Aaron Rinehart help you navigate the challenges of sustaining resilience in complex software systems by using the principles and practices of security chaos engineering. By preparing for adverse events, you can ensure they don't disrupt your ability to innovate, move quickly, and achieve your engineering and business goals"--Back cover.

"Learn how to build end-to-end scalable machine learning solutions with Apache Spark. With this practical guide, author Adi Polak introduces data and ML practitioners to creative solutions that supersede today's traditional methods. You'll learn a more holistic approach that takes you beyond specific requirements and organizational goals--allowing data and ML practitioners to collaborate and understand each other better ... [Also] examines several technologies for building end-to-end distributed ML workflows based on the Apache Spark ecosystem with Spark MLlib, MLflow, TensorFlow, and PyTorch"--

"The past decade has witnessed the broad adoption of artificial intelligence and machine learning (AI/ML) technologies. However, a lack of oversight in their widespread implementation has resulted in some incidents and harmful outcomes that could have been avoided with proper risk management. Before we can realize AI/ML's true benefit, practitioners must understand how to mitigate its risks. This book describes approaches to responsible AI--a holistic framework for improving AI/ML technology, business processes, and cultural competencies that builds on best practices in risk management, cybersecurity, data privacy, and applied social science. Authors Patrick Hall, James Curtis, and Parul Pandey created this guide for data scientists who want to improve real-world AI/ML system outcomes for organizations, consumers, and the public."--

This practical guide shows data scientists, data engineers, architects, and business analysts how to get started with a graph database using TigerGraph, one of the leading graph database models available.

Improve the user experience for your Rails app with rich, engaging client-side interactions. Learn to use the Rails 7 tools and simplify the complex JavaScript ecosystem. It's easier than ever to build user interactions with Hotwire, Turbo, and Stimulus. You can add great front-end flair without much extra complication. Use React to build a more complex set of client-side features. Structure your code for different levels of client-side needs with these powerful options. Add to your toolkit today! It's hard to have a Rails application without integrating some client-side logic. But client-side coding tools, and the Rails tools for integrating with them, all change continuously. Rails 7 simplifies client-side integration with the Hotwire gem. It's a great way to build client interaction with server-side HTML and a small amount of JavaScript. In the latest edition of this book, learn how to use Rails 7 and its front-end bundling tools to build rich front-end logic into your Rails applications. The job is even easier with Stimulus, a library that brings Rails conventions to JavaScript tools. And you can also add in React, a larger framework that automatically updates the browser when your data changes. Learn the basics of Turbo, Stimulus, and TypeScript, and add pizazz to your application. Structure your web application to best manage your state. Learn how to interact with data on the server while still keeping the user experience interactive. Use the type system in TypeScript to expand on JavaScript and help prevent error conditions. Debug and test your front-end application with tools specific to each framework. There are a lot of ways to do client-side coding, and Rails is here to help. What You Need: This book requires Ruby on Rails 7.0 or later, React 17.0.0 or later. Other dependencies will be added by Rails.

Data has become the most powerful tool in business today, and telling its story effectively is critical. Yet one of the best communicatorscoloris the most neglected tool in data visualization. With this book, DATAcated founder Kate Strachnyi provides the ultimate guide to the correct use of color for representing data in graphs, charts, tables, and infographics.Ideal for data and business analysts, data scientists, and others who design infographics and data visualizations, this practical resource explores color tips and tricks, including the theories behind them and why they work the way they do. ColorWise covers the psychology, history, and culture of many different colors. This book is also a useful teaching tool for learning about proper use of color for data storytelling techniques and dashboarding.You'll explore:The role that color theory plays in data visualization and storytellingVarious color techniques you can use to improve data visualizationsHow colors affect your audience's understanding of data visualizationsHow to use color intentionally to help guide your audienceTips for using colors that people with color vision deficiency can interpretHow to apply the book's guidelines for use in your own projects

With millions of new users and several new models, the Raspberry Pi ecosystem continues to expandalong with a lot of new questions about the Pis capabilities. The second edition of this popular cookbook provides more than 240 hands-on recipes for running this tiny low-cost computer with Linux, programming it with Python, and hooking up sensors, motors, and other hardwareincluding Arduino and the Internet of Things.Prolific hacker and author Simon Monk also teaches basic principles to help you use new technologies with Raspberry Pi as its ecosystem continues to develop. This cookbook is ideal for programmers and hobbyists familiar with the Pi through resources, including Getting Started with Raspberry Pi (OReilly). Python and other code examples from the book are available on GitHub.Set up your Raspberry Pi and connect to a networkWork with its Linux-based operating systemProgram Raspberry Pi with PythonGive your Pi "e;eyes"e; with computer visionControl hardware through the GPIO connectorUse Raspberry Pi to run different types of motorsWork with switches, keypads, and other digital inputsUse sensors to measure temperature, light, and distanceConnect to IoT devices in various waysCreate dynamic projects with Arduino

Perform fast interactive analytics against different data sources using the Trino high-performance distributed SQL query engine. With this practical guide, you'll learn how to conduct analytics on data where it lives, whether it's Hive, Cassandra, a relational database, or a proprietary data store. Analysts, software engineers, and production engineers will learn how to manage, use, and even develop with Trino.Initially developed by Facebook, open source Trino is now used by Netflix, Airbnb, LinkedIn, Twitter, Uber, and many other companies. Matt Fuller, Manfred Moser, and Martin Traverso show you how a single Trino query can combine data from multiple sources to allow for analytics across your entire organization.Get started: Explore Trino's use cases and learn about tools that will help you connect to Trino and query dataGo deeper: Learn Trino's internal workings, including how to connect to and query data sources with support for SQL statements, operators, functions, and morePut Trino in production: Secure Trino, monitor workloads, tune queries, and connect more applications; learn how other organizations apply Trino

Is Kubernetes ready for stateful workloads? This open source system has become the primary platform for deploying and managing cloud native applications. But because it was originally designed for stateless workloads, working with data on Kubernetes has been challenging. If you want to avoid the inefficiencies and duplicative costs of having separate infrastructure for applications and data, this practical guide can help.Using Kubernetes as your platform, you'll learn open source technologies that are designed and built for the cloud. Authors Jeff Carpenter and Patrick McFadin provide case studies to help you explore new use cases and avoid the pitfalls others have faced. Youll get an insider's view of what's coming from innovators who are creating next-generation architectures and infrastructure.With this book, you will:Learn how to use basic Kubernetes resources to compose data infrastructureAutomate the deployment and operations of data infrastructure on Kubernetes using tools like Helm and operatorsEvaluate and select data infrastructure technologies for use in your applicationsIntegrate data infrastructure technologies into your overall stackExplore emerging technologies that will enhance your Kubernetes-based applications in the future

The low cost of getting started with cloud services can easily evolve into a significant expense down the road. That's challenging for teams developing data pipelines, particularly when rapid changes in technology and workload require a constant cycle of redesign. How do you deliver scalable, highly available products while keeping costs in check? With this practical guide, author Sev Leonard provides a holistic approach to designing scalable data pipelines in the cloud. Intermediate data engineers, software developers, and architects will learn how to navigate cost/performance trade-offs and how to choose and configure compute and storage. You'll also pick up best practices for code development, testing, and monitoring. By focusing on the entire design process, you'll be able to deliver cost-effective, high-quality products. This book helps you: Reduce cloud spend with lower cost cloud service offerings and smart design strategies Minimize waste without sacrificing performance by rightsizing compute resources Drive pipeline evolution, head off performance issues, and quickly debug with effective monitoring Set up development and test environments that minimize cloud service dependencies Create data pipeline code bases that are testable and extensible, fostering rapid development and evolution Improve data quality and pipeline operation through validation and testing

"Learn the core concepts of Vue.js, the modern JavaScript framework for building frontend applications and interfaces from scratch. With concise, practical, and clear examples, this book takes web developers step-by-step through the tools and libraries in the Vue.js ecosystem and shows them how to create complete applications for real-world web projects. You'll learn how to handle data communication between components with Pinia architecture, develop a manageable routing system for a frontend project to control the application flow, and produce basic animation effects to create a better user experience"--

After decades of relative obscurity, functional programming is finally coming into its own. With concise, easy-to-read code that supports asynchronous, concurrent processing, aspects of functional programming have begun to appear in several traditionally object-oriented languages such as C# and Java. This practical book shows C# programmers how to use functional programming features without having to navigate an entirely new language. Because of the shared runtime environment common to C# and F# languages, it's possible to use most of F#'s functional features in C# as well. Author Simon J. Painter explains how you can write functional code in C# right away, without having to install dependencies or features newer than .NET 3. You'll learn why functional programming concepts can bring immediate benefit to your work. Learn what functional programming is and how it originated Discover features of the functional paradigm using a more familiar language Start coding functionally in C# right away, without relying on third-party libraries Write code that's more robust, less error prone, and easier to test Examine less conventional ways to look at structures available in C# Explore the practicalities of using functional C# in a business environment.

Many organizations today analyze and share large, sensitive datasets about individuals. Whether these datasets cover healthcare details, financial records, or exam scores, it's become more difficult for organizations to protect an individual's information through deidentification, anonymization, and other traditional statistical disclosure limitation techniques. This practical book explains how differential privacy (DP) can help. Authors Ethan Cowan, Michael Shoemate, and Mayana Pereira explain how these techniques enable data scientists, researchers, and programmers to run statistical analyses that hide the contribution of any single individual. You'll dive into basic DP concepts and understand how to use open source tools to create differentially private statistics, explore how to assess the utility/privacy trade-offs, and learn how to integrate differential privacy into workflows. With this book, you'll learn: How DP guarantees privacy when other data anonymization methods don't What preserving individual privacy in a dataset entails How to apply DP in several real-world scenarios and datasets Potential privacy attack methods, including what it means to perform a reidentification attack How to use the OpenDP library in privacy-preserving data releases How to interpret guarantees provided by specific DP data releases

If your organization plans to modernize services and move to the cloud from legacy software or a private cloud on premises, this book is for you. Software developers, solution architects, cloud engineers, and anybody interested in cloud technologies will learn fundamental concepts for cloud computing, migration, transformation, and development using Microsoft Azure. Author and Microsoft MVP Jonah Carrio Andersson guides you through cloud computing concepts and deployment models, the wide range of modern cloud technologies, application development with Azure, team collaboration services, security services, and cloud migration options in Microsoft Azure. You'll gain insight into the Microsoft Azure cloud services that you can apply in different business use cases, software development projects, and modern solutions in the cloud. You'll also become fluent with Azure cloud migration services, serverless computing technologies that help your development team work productively, Azure IoT, and Azure cognitive services that make your application smarter. This book also provides real-world advice and best practices based on the author's own Azure migration experience.

"As an aspiring data scientist, you appreciate why organizations rely on data for important decisions--whether it's for companies designing websites, cities deciding how to improve services, or scientists discovering how to stop the spread of disease. And you want the skills required to distill a messy pile of data into actionable insights. We call this the data science lifecycle: the process of collecting, wrangling, analyzing, and drawing conclusions from data. [This] is the first book to cover foundational skills in both programming and statistics that encompass this entire lifecycle. It's aimed at those who wish to become data scientists or who already work with data scientists, and at data analysts who wish to cross the 'technical/nontechnical' divide. If you have a basic knowledge of Python programming, you'll learn how to work with data using industry-standard tools like pandas"--

Building a simple but powerful recommendation system is much easier than you think. Approachable for all levels of expertise, this report explains innovations that make machine learning practical for business production settingsand demonstrates how even a small-scale development team can design an effective large-scale recommendation system.Apache Mahout committers Ted Dunning and Ellen Friedman walk you through a design that relies on careful simplification. Youll learn how to collect the right data, analyze it with an algorithm from the Mahout library, and then easily deploy the recommender using search technology, such as Apache Solr or Elasticsearch. Powerful and effective, this efficient combination does learning offline and delivers rapid response recommendations in real time.Understand the tradeoffs between simple and complex recommendersCollect user data that tracks user actionsrather than their ratingsPredict what a user wants based on behavior by others, using Mahoutfor co-occurrence analysisUse search technology to offer recommendations in real time, complete with item metadataWatch the recommender in action with a music service exampleImprove your recommender with dithering, multimodal recommendation, and other techniques

Want to create animated graphics for iPhone, iPad and the Web, using familiar Adobe features? Youve come to the right guide. Adobe Edge Preview 5: The Missing Manual shows you how to build HTML5 and JavaScript graphics with Adobe multimedia tools. No programming experience? No problem. Adobe Edge writes all the code for you. With this book, youll be designing great-looking web apps in no time.The important stuff you need to know:Get to know the workspace. Learn how Adobe Edge Preview 5 performs its magic.Create and import graphics. Make drawings with Edges tools, or use art you designed in other programs.Work with text. Build menus, label buttons, provide instructions, and perform other tasks.Jump into animation. Master Edges elements, properties, and timeline panels.Make it interactive. Use triggers and actions to give users control over their web experience.Peek behind the curtain. Understand how HTML and CSS documents work.Dig into JavaScript. Customize your projects by tweaking your code.

Want to perform programming tasks better, faster, simpler, and make them repeatable? Take a deep dive into Windows PowerShell and discover what this distributed automation platform can do. Whether youre a .NET developer or IT pro, this concise guide will show you how PowerShells scripting language can help you be more productive on everyday tasks.Quickly learn how to create PowerShell scripts and embed them into your existing applications, write "e;little languages"e; to solve specific problems, and take charge of your code. This book includes example scripts that you can easily pull apart, tweak, and then use in your own PowerShell and .NET solutions.Slice and dice text, XML, CSV, and JSON with easeEmbed PowerShell to provide scripting capabilities for your C# appsCreate GUI applications five to ten times faster with less codeLeverage PowerShells capabilities to work with the InternetInteract with DLLs and create objects, automatically display properties, and call methods in live interactive sessionsBuild domain-specific languages (DSLs) and vocabularies to express solutions more clearlyWork with Microsoft Office via the Component Object Model (COM)Discover PowerShell v3 features included with Windows 8 and Windows Server 2012

The Internet's "e;killer app"e; is not the World Wide Web or Push technologies: it is humble electronic mail. More people use email than any other Internet application. As the number of email users swells, and as email takes on an ever greater role in personal and business communication, Internet mail protocols have become not just an enabling technology for messaging, but a programming interface on top of which core applications are built.Programming Internet Email unmasks the Internet Mail System and shows how a loose federation of connected networks have combined to form the world's largest and most heavily trafficked message system.Programming Internet Email tames the Internet's most popular messaging service. For programmers building applications on top of email capabilities, and power users trying to get under the hood of their own email systems, Programming Internet Email stands out as an essential guide and reference book. In typical O'Reilly fashion,Programming Internet Email covers the topic with nineteen tightly written chapters and five useful appendixes.Following a thorough introduction to the Internet Mail System, the book is divided into five parts:Part I covers email formats, from basic text messages to the guts of MIME. Secure email message formats (OpenPGP and S/MIME), mailbox formats and other commonly used formats are detailed in this reference section.Part II describes Internet email protocols: SMTP and ESMTP, POP3 and IMAP4. Each protocol is covered in detail to expose the Internet Mail System's inner workings.Part III provides a solid API reference for programmers working in Perl and Java. Class references are given for commonly used Perl modules that relate to email and the Java Mail API.Part IV provides clear and concise examples of how to incorporate email capabilities into your applications. Examples are given in both Perl and Java.Part V covers the future of email on the Internet. Means and methods for controlling spam email and newly proposed Internet mail protocols are discussed.Appendixes to Programming Internet Email provide a host of explanatory information and useful references for the programmer and avid user alike, including a comprehensive list of Internet RFCs relating to email, MIME types and a list of email related URLs.Programming Internet Email will answer all of your questions about mail and extend your abilities into this most popular messaging frontier.

The perimeter defenses guarding your network perhaps are not as secure as you think. Hosts behind the firewall have no defenses of their own, so when a host in the "e;trusted"e; zone is breached, access to your data center is not far behind. Thats an all-too-familiar scenario today. With this practical book, youll learn the principles behind zero trust architecture, along with details necessary to implement it.The Zero Trust Model treats all hosts as if theyre internet-facing, and considers the entire network to be compromised and hostile. By taking this approach, youll focus on building strong authentication, authorization, and encryption throughout, while providing compartmentalized access and better operational agility.Understand how perimeter-based defenses have evolved to become the broken model we use todayExplore two case studies of zero trust in production networks on the client side (Google) and on the server side (PagerDuty)Get example configuration for open source tools that you can use to build a zero trust networkLearn how to migrate from a perimeter-based network to a zero trust network in production

BioCoder is a quarterly newsletter for DIYbio, synthetic bio, and anything related. You'll discover:Articles about interesting projects and experiments, such as the glowing plantArticles about tools, both those you buy and those you buildVisits to DIYbio laboratoriesProfiles of key people in the communityAnnouncements of events and other items of interestSafety pointers and tips about good laboratory practiceAnything that's interesting or useful: you tell us!And BioCoder is free (for the time being), unless you want a dead-tree version. We'd like BioCoder to become self supporting (maybe even profitable), but we'll worry about that after we've got a few issues under our belt.If you'd like to contribute, send email to BioCoder@oreilly.com. Tell us what you'd like to do, and we'll get you started.