Exploring the role of the nervous system for understanding depression in spinal cord injury

The Neurovisceral Integration theory conceptualizes the nervous system's role in
understanding health and well-being. The theory describes a set of neural structures,
including the central and the autonomic nervous system involved in generating goaloriented
responses (Thayer & Lane, 2000, 2009). These goal-oriented responses
regulate the affect and cognitive processes (Thayer & Lane, 2009) influencing mental
health. The thesis explores the nervous system's role in depression in spinal cord injury.
The Neurovisceral Integration theory postulates that the central and autonomic
nervous system(CNS-ANS) interact in affect and cognitive processes. This CNS-ANS
interaction inhibits ongoing behavior, providing regulation and flexibility for goaloriented
behavior(Thayer & Lane, 2000, 2009). Affect is a psychophysiological
construct and studied using the dimension of valence and arousal.(Appelhans &
Luecken, 2006a; Kuppens et al., 2013; Thayer & Lane, 2000). Valence denotes the
individual's understanding of the pleasantness and unpleasantness of a stimulus,
whereas arousal denotes the activation of the autonomic nervous system in response to
the stimuli. (Hagemann et al., 2003a; Thayer, Hansen, Saus-Rose, et al., 2009; Thayer
& Lane, 2000, 2009; Thayer & Siegle, 2002). Cognition refers to the mental processes
such as thinking, problem-solving, and decision-making that benefit from inhibitory
control. The inhibitory control is required for an individual to shift attention from
existing behavior to goal-oriented behavior (Thayer & Lane, 2009).