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Fermented Cholesterol Lowering Drug (Lovastatin)

Fermented Cholesterol Lowering Drug (Lovastatin)af Sadia Javed
Bag om Fermented Cholesterol Lowering Drug (Lovastatin)

Lovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. In western countries, the most significant cause of death is the coronary heart disease and progression of atherosclerosis which is mostly related to the hypercholesterolemia. Approximately 10.8% of all deaths are caused due to this disease. Coronary heart disease actually is a wide assortment of diseases. It has been reported that 30 million people have familial hypercholesterolemia worldwide, but less than 1% of cases are diagnosed in most countries. A lab experiment was carried out for fungal production of lovastatin in solid state fermentation. Fermentation medium was optimized by optimizing the fermentation parameters (pH, temperature, inoculum size, moisture contents etc.).

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9783845475158
  • Indbinding:
  • Paperback
  • Sideantal:
  • 104
  • Udgivet:
  • 10. oktober 2013
  • Størrelse:
  • 150x7x220 mm.
  • Vægt:
  • 173 g.
  • BLACK WEEK
Leveringstid: 2-3 uger
Forventet levering: 12. december 2024

Beskrivelse af Fermented Cholesterol Lowering Drug (Lovastatin)

Lovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. In western countries, the most significant cause of death is the coronary heart disease and progression of atherosclerosis which is mostly related to the hypercholesterolemia. Approximately 10.8% of all deaths are caused due to this disease. Coronary heart disease actually is a wide assortment of diseases. It has been reported that 30 million people have familial hypercholesterolemia worldwide, but less than 1% of cases are diagnosed in most countries. A lab experiment was carried out for fungal production of lovastatin in solid state fermentation. Fermentation medium was optimized by optimizing the fermentation parameters (pH, temperature, inoculum size, moisture contents etc.).

Brugerbedømmelser af Fermented Cholesterol Lowering Drug (Lovastatin)



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